Cardiovascular disease remains the primary cause of morbidity and mortality in the developed world. There continues to be a need for outstanding scientist-educators to increase our basic understanding of cardiovascular disease and to translate this information into clinical application. The Training Program in """"""""Molecular Physiology of the Cardiovascular System"""""""" (MFCS) at Baylor College of Medicine is a multidisciplinary program with 32 participating faculty from 7 basic science and 9 clinical departments. The MFCS training program has trained 32 predoctoral and 68 postdoctoral trainees since its inception in 1989. Currently, the mentors are primarily located at Baylor College of Medicine (BCM), Rice University (RU), MD Anderson Cancer Center, Methodist Hospital, and the Texas A&M Health Sciences Center Institute for Biosciences and Biotechnology (IBT). The major goal for our program is to train biomedical scientists (5 predoctoral and 7 postdoctoral trainees) to work at the interface of basic and clinical research in one of four specialized themes, related to cardiovascular research. These themes include: 1) Electrophyslology & excitability, 2) Development and stem cells, 3) Stroke and cerebrovascular disease, and 4) Tissue engineering and novel therapeutic strategies. The strong collaborative research infrastructure at Baylor College of Medicine and partner institutions in the Texas Medical Center, and the diverse background of our mentors (basic scientists and practicing clinicians), provide unique resources for the trainees affiliated with the MFCS training program. The MFCS trainees will participate in an interdisciplinary training program comprised of didactic courses, grant writing workshops, journal clubs, seminar series, ethics training, and regular interactions with training faculty. Moreover, the pre- and postdoctoral fellows will be trained as leaders of teams of scientists and physicians that collaborate in translational research.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007676-25
Application #
8725719
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Wang, Wayne C
Project Start
1994-07-01
Project End
2015-08-31
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
25
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77030
Giudice, Jimena; Loehr, James A; Rodney, George G et al. (2016) Alternative Splicing of Four Trafficking Genes Regulates Myofiber Structure and Skeletal Muscle Physiology. Cell Rep 17:1923-1933
Quick, Ann P; Landstrom, Andrew P; Wehrens, Xander H T (2016) Junctophilin-2 at the intersection of arrhythmia and pathologic cardiac remodeling. Heart Rhythm 13:753-4
Singh, Manmohan; Raghunathan, Raksha; Piazza, Victor et al. (2016) Applicability, usability, and limitations of murine embryonic imaging with optical coherence tomography and optical projection tomography. Biomed Opt Express 7:2295-310
Huq, Redwan; Samuel, Errol L G; Sikkema, William K A et al. (2016) Preferential uptake of antioxidant carbon nanoparticles by T lymphocytes for immunomodulation. Sci Rep 6:33808
Ha, Kyungsoo; Shen, Yiping; Graves, Tyler et al. (2016) The presence of two rare genomic syndromes, 1q21 deletion and Xq28 duplication, segregating independently in a family with intellectual disability. Mol Cytogenet 9:74
Wu, Chen; Sudheendran, Narendran; Singh, Manmohan et al. (2016) Rotational imaging optical coherence tomography for full-body mouse embryonic imaging. J Biomed Opt 21:26002
Pethő, Zoltán; Tanner, Mark R; Tajhya, Rajeev B et al. (2016) Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes. Arthritis Res Ther 18:103
Connell, Patrick S; Azimuddin, Anam F; Kim, Seulgi E et al. (2016) Regurgitation Hemodynamics Alone Cause Mitral Valve Remodeling Characteristic of Clinical Disease States In Vitro. Ann Biomed Eng 44:954-67
Fortune, Ryan D; Grill, Raymond J; Beeton, Christine et al. (2016) Changes in Gene Expression and Metabolism in the Testes of the Rat following Spinal Cord Injury. J Neurotrauma :
Inoue, Taeko; Griffin, Deric M; Huq, Redwan et al. (2016) Characterization of a novel MR-detectable nanoantioxidant that mitigates the recall immune response. NMR Biomed 29:1436-44

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