This training program provides two years of basic research training in vascular surgery for academic clinicians. It addresses the absence of adequate research training for vascular surgeons as it applies to specific areas of clinical disease. Research training in molecular and cell biology, biomechanics, coagulation thrombosis, and angiogenesis is provided with a focus on clinically relevant problems such as atherogenesis, intimal hyperplasia, prosthetic/host interactions and thrombosis. A new component is the availability of mentored advanced outcomes research training Trainees pursue a program of intense research activity supplemented with course work in research design, statistics, and evaluation of published research. The program is conducted and closely supervised by the program director, co-director and mentors who have well-established records of peer-reviewed research, and who were selected both for the current research activities and their proven commitment to train research fellows. Individual mentors are chosen from the program's faculty on the basis of the background and research interest of the individual trainee, and the trainees carry out their own projects under the close guidance of their mentor. Laboratory training can be supplemented by graduate level training at Harvard Medical School the Department of Health Care Policy and Research and Harvard's Faculty of Arts and Sciences, with course selection complementing laboratory endeavors. Upon completion of the program, trainees are capable of independent research and possess the scientific and research background needed to obtain competitive peer-reviewed grants;they have the abilities and knowledge necessary to provide translational expertise as they join medical school faculties. Selection of the trainees is based on candidates'demonstrated ability and career choice of academic practice. Applicants are resident physicians who have completed two, three or five years (i.e. is board eligible) of post-graduate surgical training. Trainees commit to two years of training;trainees desiring a shorter training period are not considered. Only those applicants with career goals in academic surgery, with a keen interest in basic resarch or outcomes research in vascular surgery, are compatible. Candidates pursuing a fellowship during a program of clinical traning must provide evidence that they will be accepted back into that program upon completion of their research training. Trainees are not involved in any clinical activities unless research related.

Public Health Relevance

Vascular Surgeons provide a practical """"""""hands on"""""""" perspective on the relevant problems of devices and interventions on blood vessels. This program creates a cadre of surgeons with expertise in research fundamentals essential to frontline 'bench to bedside to public policy'programs in treatment of vascular disease.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007734-20
Application #
8502722
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Carlson, Drew E
Project Start
1997-07-01
Project End
2014-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
20
Fiscal Year
2013
Total Cost
$436,021
Indirect Cost
$35,972
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215
Servais, Andrew B; Kienzle, Arne; Ysasi, Alexandra B et al. (2018) Structural heteropolysaccharides as air-tight sealants of the human pleura. J Biomed Mater Res B Appl Biomater :
Shean, Katie E; O'Donnell, Thomas F X; Deery, Sarah E et al. (2018) Regional variation in patient outcomes in carotid artery disease treatment in the Vascular Quality Initiative. J Vasc Surg 68:749-759
Kienzle, Arne; Servais, Andrew B; Ysasi, Alexandra B et al. (2018) Free-Floating Mesothelial Cells in Pleural Fluid After Lung Surgery. Front Med (Lausanne) 5:89
Baker, Meredith A; Mitchell, Paul D; O'Loughlin, Alison A et al. (2018) Characterization of Fatty Acid Profiles in Infants With Intestinal Failure-Associated Liver Disease. JPEN J Parenter Enteral Nutr 42:71-77
Deery, Sarah E; O'Donnell, Thomas F X; Zettervall, Sara L et al. (2018) Use of an Assistant Surgeon Does not Mitigate the Effect of Lead Surgeon Volume on Outcomes Following Open Repair of Intact Abdominal Aortic Aneurysms. Eur J Vasc Endovasc Surg 55:714-719
Liang, Patric; Soden, Peter A; Zettervall, Sara L et al. (2018) Treatment outcomes in diabetic patients with chronic limb-threatening ischemia. J Vasc Surg 68:487-494
Shean, Katie E; Zettervall, Sara L; Deery, Sarah E et al. (2018) Fewer Complications in the Obese Following Lower Extremity Endovascular Interventions. Ann Vasc Surg 49:17-23
Buck, Dominique B; Soden, Peter A; Deery, Sarah E et al. (2018) Comparison of Endovascular Stent Grafts for Abdominal Aortic Aneurysm Repair in Medicare Beneficiaries. Ann Vasc Surg 47:31-42
O'Donnell, Thomas F X; Schermerhorn, Marc L; Liang, Patric et al. (2018) Weekend Effect in Carotid Endarterectomy. Stroke 49:2945-2952
Baker, Meredith A; Nandivada, Prathima; Mitchell, Paul D et al. (2018) Pretreatment with intravenous fish oil reduces hepatic ischemia reperfusion injury in a murine model. Surgery 163:1035-1039

Showing the most recent 10 out of 276 publications