This research training program in pulmonary and critical care medicine, open to MD's that have completed their residency training and PhD's in health sciences, is in its fourth year. It is designed to provide 2 to 3 years of support for trainees in clinical and translational research and offers optional participation in the Vanderbilt Master of Science in Clinical Investigation (MSCI) and Master of Public Health (MPH) programs. To date, 7 trainees have joined the program, 5 MD's and 2 PhD's, 3 have participated in the MSCI program. There are 4 junior faculty participating in the mentor-in-training arm of the program. Given the success of the first 4 years, we are requesting renewal of funding support. Remarkable advances in the prevention, cure, and management of acute and chronic disease have occurred in past decades. However, there is growing national concern that expert clinical investigators who can translate new research findings to practice are decreasing in numbers. It has never been more important to create and maintain a cadre of physician-scientists, given the unprecedented developments at the cellular and molecular level, including knowledge of the human genome. Innovation in selection, training and career development of new investigators is greatly needed. Vanderbilt University has a very successful history in developing well trained researchers who have the vision and the skills with which to embark on successful careers in academic research, both basic and clinical. This training program, """"""""Clinical and Translational Research Training Program in Pulmonary Medicine"""""""" will focus on training and mentoring researchers in all aspects of clinical and translational research necessary to prepare them for the unique challenges associated with advancing science in Pulmonary and Critical Care Medicine. Although clinically oriented, the program includes an introduction to the basic mechanisms of disease and the importance of collaborating with basic researchers in hypothesizing and designing clinical research and offers trainees opportunities to explore hypotheses anywhere on the continuum of translational research. This training program accepts two new trainees per year (maximum 4 participants/yr). Applicants who show exceptional aptitude for successfully pursuing an academic research career are considered for participation. The program concentrates on developing expertise in three core areas: Asthma, Pulmonary Hypertension and Critical Care Research;areas of national recognition and presence for Vanderbilt. The Program Director's lead a team of experts in these areas who are engaged in successful academic research careers who play significant roles in supporting trainees in developing skills in understanding research;applying those skills;identifying and resolving research related process problems;and understanding and applying the principals of responsible conduct of research;in ways that will prepare them to utilize the skills they acquire in the pursuit of future academic research careers.
It has never been more important to create and maintain a cadre of basic and physician-scientists who collaborate to make rapid progress in determining mechanisms of disease and opportunities for new therapies. This training program in clinical and translational research will prepare future researchers for the unique challenges associated with advancing science and public health in the specialty of pulmonary and critical care medicine.
|Assad, Tufik R; Hemnes, Anna R; Larkin, Emma K et al. (2016) Clinical and Biological Insights Into Combined Post- and Pre-Capillary Pulmonary Hypertension. J Am Coll Cardiol 68:2525-2536|
|Janz, David R; Semler, Matthew W; Lentz, Robert J et al. (2016) Randomized Trial of Video Laryngoscopy for Endotracheal Intubation of Critically Ill Adults. Crit Care Med 44:1980-1987|
|Hay, Bryan R; Pugh, Meredith E; Robbins, Ivan M et al. (2016) Parenteral Prostanoid Use at a Tertiary Referral Center: A Retrospective Cohort Study. Chest 149:660-6|
|Semler, Matthew W; Wheeler, Arthur P; Thompson, B Taylor et al. (2016) Impact of Initial Central Venous Pressure on Outcomes of Conservative Versus Liberal Fluid Management in Acute Respiratory Distress Syndrome. Crit Care Med 44:782-9|
|Winters, Christopher J; Koval, Olha; Murthy, Shubha et al. (2016) CaMKII inhibition in type II pneumocytes protects from bleomycin-induced pulmonary fibrosis by preventing Ca2+-dependent apoptosis. Am J Physiol Lung Cell Mol Physiol 310:L86-94|
|Kangelaris, Kirsten Neudoerffer; Ware, Lorraine B; Wang, Chen Yu et al. (2016) Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. Crit Care Med 44:120-9|
|Landsperger, Janna S; Semler, Matthew W; Wang, Li et al. (2016) Outcomes of Nurse Practitioner-Delivered Critical Care: A Prospective Cohort Study. Chest 149:1146-54|
|Semler, Matthew W; Marney, Annis M; Rice, Todd W et al. (2016) B-Type Natriuretic Peptide, Aldosterone, and Fluid Management in ARDS. Chest 150:102-11|
|Shaver, Ciara M; Upchurch, Cameron P; Janz, David R et al. (2016) Cell-free hemoglobin: a novel mediator of acute lung injury. Am J Physiol Lung Cell Mol Physiol 310:L532-41|
|Norman, Brett C; Jackson, James C; Graves, John A et al. (2016) Employment Outcomes After Critical Illness: An Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychological Dysfunction in ICU Survivors Cohort. Crit Care Med 44:2003-2009|
Showing the most recent 10 out of 87 publications