Although noninvasive imaging can be used to facilitate delivery of cardiovascular healthcare, there are relatively few academic physicians and doctorate awarded professionals that are trained to direct research dedicated to the appropriate application of imaging in populations with cardiovascular disease. This is an important issue to address given that in 2008, imaging will supplant pharmaceuticals as the largest healthcare expenditure for Medicare and Medicaid in the United States. This T32 application is designed for postdoctoral MD and PhD investigators who are transitioning from doctoral training into investigative research careers in health sciences research using cardiovascular imaging. Each enrolled investigator will be partnered with an established noninvasive cardiovascular-imaging research mentor in order to receive academic training for the purpose of performing meaningful research studies dedicated toward the appropriate use of imaging for delivering cardiovascular healthcare. Other key features of this T-32 application include: 1) all program trainees will enroll in a Master's of Science degree program in Clinical &Population Translational Sciences, 2) an organizational multi-disciplinary program structure that is adept at training young investigators and has the capability to recognize, modify, and adapt this T-32 program for the purpose of insuring that trainees are progressing toward success in academic medicine, 3) access to multiple phenotypic and biologic materials from many of the major NIH-funded prospective cohort studies and clinical trials made possible because of the extensive involvement of the ongoing research of the supporting program faculty, and 4) a seminar program that enhances interaction among performers and users of noninvasive imaging including those with expertise in bioinformatics, biomedical engineering, nanotechnology, tissue regeneration, business administration, and the cardiovascular, neurologic, surgical, and radiologic sciences. It is the goal of this T-32 program to train professional academic investigators who are well equipped to apply new advances in cardiovascular imaging with a strong health sciences research background in order to direct the application of imaging toward the improvement of cardiovascular health.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL091824-04
Application #
8308496
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Scott, Jane
Project Start
2009-09-01
Project End
2014-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
4
Fiscal Year
2012
Total Cost
$246,068
Indirect Cost
$14,672
Name
Wake Forest University Health Sciences
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
937727907
City
Winston-Salem
State
NC
Country
United States
Zip Code
27157
Stacey, R Brandon; Vera, Trinity; Morgan, Timothy M et al. (2018) Asymptomatic myocardial ischemia forecasts adverse events in cardiovascular magnetic resonance dobutamine stress testing of high-risk middle-aged and elderly individuals. J Cardiovasc Magn Reson 20:75
Hall, Michael E; Rocco, Michael V; Morgan, Timothy M et al. (2016) Beta-Blocker Use Is Associated with Higher Renal Tissue Oxygenation in Hypertensive Patients Suspected of Renal Artery Stenosis. Cardiorenal Med 6:261-8
Hall, Michael E; Brinkley, Tina E; Chughtai, Haroon et al. (2016) Adiposity Is Associated with Gender-Specific Reductions in Left Ventricular Myocardial Perfusion during Dobutamine Stress. PLoS One 11:e0146519
Vera, Trinity; D'Agostino Jr, Ralph B; Jordan, Jennifer H et al. (2015) Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy. Am J Cardiol 116:1752-5
Whitlock, Matthew C; Hundley, W Gregory (2015) Noninvasive Imaging of Flow and Vascular Function in Disease of the Aorta. JACC Cardiovasc Imaging 8:1094-1106
Whitlock, Matthew C; Yeboah, Joseph; Burke, Gregory L et al. (2015) Cancer and Its Association With the Development of Coronary Artery Calcification: An Assessment From the Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc 4:
Stacey, Richard Brandon; Andersen, Mousumi; Haag, Jason et al. (2014) Right ventricular morphology and systolic function in left ventricular noncompaction cardiomyopathy. Am J Cardiol 113:1018-23
Jordan, Jennifer H; D'Agostino Jr, Ralph B; Hamilton, Craig A et al. (2014) Longitudinal assessment of concurrent changes in left ventricular ejection fraction and left ventricular myocardial tissue characteristics after administration of cardiotoxic chemotherapies using T1-weighted and T2-weighted cardiovascular magnetic resonan Circ Cardiovasc Imaging 7:872-9
Kongbundansuk, Suwat; Hundley, W Gregory (2014) Noninvasive imaging of cardiovascular injury related to the treatment of cancer. JACC Cardiovasc Imaging 7:824-38
Jordan, Jennifer H; Haag, Jason C; Morgan, Timothy M et al. (2014) Small, short-duration, dobutamine-induced perfusion defects are not associated with adverse prognosis in intermediate-risk individuals receiving cardiovascular magnetic resonance stress imaging. J Comput Assist Tomogr 38:427-33

Showing the most recent 10 out of 16 publications