This T32 Vascular Surgery Education and Research Training (VascTrain) Program is designed to train vascular surgery residents in the fundamentals of basic and clinical cardiovascular research. This will be accomplished using a training committee comprised of a principal trainer and a team of associate trainers in a closely supervised training program. The training scheme is based on interactions between the training committee and the trainee in the form of weekly training research sessions. The VascTrain Program is integrated into a Vascular Surgery residency program where all residents participate in a 2 year curriculum designed to provide research training. Funding for 3 positions is sought to support trainees who will enter the program after 3 years of vascular surgery or surgery residency. A few PhD post-doctoral fellows will be accepted into this program. The research areas of focus are based on cardiovascular diseases, its consequences and its treatments. General areas of investigation include the pathogenesis and treatment of intimal hyperplasia, tissue engineered autologous conduits, tissue ischemia induced angiogenesis and wound healing, computational analysis of aortic aneurysm progress and rupture, cardiovascular imaging, epidemiology of cardiovascular disease, and pharmacotherapeutics. The program introduces a multidisciplinary approach to vascular biology research and a dedicated approach to clinical/translational research.
|Madigan, Michael; Entabi, Fateh; Zuckerbraun, Brian et al. (2015) Delayed inhaled carbon monoxide mediates the regression of established neointimal lesions. J Vasc Surg 61:1026-33|
|Wallace, Justin R; Yuo, Theodore; Marone, Luke et al. (2014) Outcomes of endovascular lower extremity interventions depend more on indication than physician specialty. J Vasc Surg 59:376-383.e3|
|Sharifi-Sanjani, Maryam; Shoushtari, Ali Hakim; Quiroz, Marisol et al. (2014) Cardiac CD47 drives left ventricular heart failure through Ca2+-CaMKII-regulated induction of HDAC3. J Am Heart Assoc 3:e000670|
|Whelan, Sean P; Carchman, Evie H; Kautza, Benjamin et al. (2014) Polymicrobial sepsis is associated with decreased hepatic oxidative phosphorylation and an altered metabolic profile. J Surg Res 186:297-303|
|Kiguchi, Misaki M; Hager, Eric S; Winger, Daniel G et al. (2014) Factors that influence perforator thrombosis and predict healing with perforator sclerotherapy for venous ulceration without axial reflux. J Vasc Surg 59:1368-76|
|Rogers, Natasha M; Sharifi-Sanjani, Maryam; Csányi, Gábor et al. (2014) Thrombospondin-1 and CD47 regulation of cardiac, pulmonary and vascular responses in health and disease. Matrix Biol 37:92-101|
|Jeyabalan, Geetha; Wallace, Justin R; Chaer, Rabih Antoine et al. (2014) Endovascular strategies for treatment of embolizing thoracoabdominal aortic lesions. J Vasc Surg 59:1256-64|