This is a new application to fund Pulmonary research training at the University of Texas Southwestern Medical Center, at the postdoctoral (MD, PhD) level. The proposal is born out of a collaborative effort between the Pediatric and Adult divisions involved in lung research at this Institute, and is thus interdepartmental at its core. Twenty six funded, experienced investigators representing 12 different clinical and basic science departments and centers form a solid, diverse training force, organized into four thematic tracks: 1) Pulmonary vascular disease;2) Interstitial lung diseases;3) Lung epithelial cell and differentiation disorders;and 4) Immunity/Inflammation/Sepsis. Trainees will be paired with one of our mentors and enter one of these four tracks. Besides mentor-based teaching, trainees will receive a comprehensive track- and project-specific didactic curriculum. Both clinical and basic science trainees will be guided by an individualized advisory committee that has both basic and clinical science mentors, to broaden the trainee's perspective and facilitate bench to bedside thinking. Emphasis will be placed on maintenance of project focus, creative experimental design, state of the art technology, and careful early career guidance. The strength of this program lies in the highly collaborative Institutional environment, the unique interdepartmental leadership and training faculty of the program, and the experienced and dedicated faculty serving as trainers.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Colombini-Hatch, Sandra
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Texas Sw Medical Center Dallas
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Chambliss, Ken L; Barrera, Jose; Umetani, Michihisa et al. (2016) Nonnuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice. Endocrinology 157:3731-3741
Morrow, K Adam; Ochoa, Cristhiaan D; Balczon, Ron et al. (2016) Pseudomonas aeruginosa exoenzymes U and Y induce a transmissible endothelial proteinopathy. Am J Physiol Lung Cell Mol Physiol 310:L337-53
Cho, Geoffrey W; Altamirano, Francisco; Hill, Joseph A (2016) Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death. Biochim Biophys Acta 1862:763-77
Ulrich, Victoria; Gelber, Shari E; Vukelic, Milena et al. (2016) ApoE Receptor 2 Mediation of Trophoblast Dysfunction and Pregnancy Complications Induced by Antiphospholipid Antibodies in Mice. Arthritis Rheumatol 68:730-9
Regan, Erin; Sibley, Robert C; Cenik, Bercin Kutluk et al. (2016) Identification of Gene Expression Differences between Lymphangiogenic and Non-Lymphangiogenic Non-Small Cell Lung Cancer Cell Lines. PLoS One 11:e0150963
Philley, Julie V; Wallace Jr, Richard J; Benwill, Jeana L et al. (2015) Preliminary Results of Bedaquiline as Salvage Therapy for Patients With Nontuberculous Mycobacterial Lung Disease. Chest 148:499-506
Morrow, K A; Seifert, R; Kaever, V et al. (2015) Heterogeneity of pulmonary endothelial cyclic nucleotide response to Pseudomonas aeruginosa ExoY infection. Am J Physiol Lung Cell Mol Physiol 309:L1199-207
Philley, Julie V; Griffith, David E (2015) Treatment of slowly growing mycobacteria. Clin Chest Med 36:79-90
Xin, Wenkuan; Feinstein, Wei P; Britain, Andrea L et al. (2015) Estimating the magnitude of near-membrane PDE4 activity in living cells. Am J Physiol Cell Physiol 309:C415-24
Tokman, Sofya; Singer, Jonathan P; Devine, Megan S et al. (2015) Clinical outcomes of lung transplant recipients with telomerase mutations. J Heart Lung Transplant 34:1318-24

Showing the most recent 10 out of 20 publications