This is a new application to fund Pulmonary research training at the University of Texas Southwestern Medical Center, at the postdoctoral (MD, PhD) level. The proposal is born out of a collaborative effort between the Pediatric and Adult divisions involved in lung research at this Institute, and is thus interdepartmental at its core. Twenty six funded, experienced investigators representing 12 different clinical and basic science departments and centers form a solid, diverse training force, organized into four thematic tracks: 1) Pulmonary vascular disease;2) Interstitial lung diseases;3) Lung epithelial cell and differentiation disorders;and 4) Immunity/Inflammation/Sepsis. Trainees will be paired with one of our mentors and enter one of these four tracks. Besides mentor-based teaching, trainees will receive a comprehensive track- and project-specific didactic curriculum. Both clinical and basic science trainees will be guided by an individualized advisory committee that has both basic and clinical science mentors, to broaden the trainee's perspective and facilitate bench to bedside thinking. Emphasis will be placed on maintenance of project focus, creative experimental design, state of the art technology, and careful early career guidance. The strength of this program lies in the highly collaborative Institutional environment, the unique interdepartmental leadership and training faculty of the program, and the experienced and dedicated faculty serving as trainers.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL098040-05
Application #
8499394
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Colombini-Hatch, Sandra
Project Start
2009-09-01
Project End
2014-08-31
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
5
Fiscal Year
2013
Total Cost
$139,695
Indirect Cost
$27,429
Name
University of Texas Sw Medical Center Dallas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Maryoung, Lindley; Yue, Yangbo; Young, Ashley et al. (2017) Somatic mutations in telomerase promoter counterbalance germline loss-of-function mutations. J Clin Invest 127:982-986
Newton, Chad A; Kozlitina, Julia; Lines, Jefferson R et al. (2017) Telomere length in patients with pulmonary fibrosis associated with chronic lung allograft dysfunction and post-lung transplantation survival. J Heart Lung Transplant 36:845-853
Sacharidou, Anastasia; Shaul, Philip W; Mineo, Chieko (2017) New Insights in the Pathophysiology of Antiphospholipid Syndrome. Semin Thromb Hemost :
Wu, Ru Feng; Liao, Chengxu; Hatoum, Hadi et al. (2017) RasGRF Couples Nox4-Dependent Endoplasmic Reticulum Signaling to Ras. Arterioscler Thromb Vasc Biol 37:98-107
Rowe, Regina K; Pyle, David M; Tomlinson, Andrew R et al. (2017) IgE cross-linking impairs monocyte antiviral responses and inhibits influenza-driven TH1 differentiation. J Allergy Clin Immunol 140:294-298.e8
Adams, Traci; Newton, Chad; Patel, Hetal et al. (2017) Resident versus faculty member simulation debriefing. Clin Teach :
Kasiri, Sahba; Shao, Chunli; Chen, Baozhi et al. (2017) GLI1 Blockade Potentiates the Antitumor Activity of PI3K Antagonists in Lung Squamous Cell Carcinoma. Cancer Res 77:4448-4459
Mathai, Susan K; Newton, Chad A; Schwartz, David A et al. (2016) Pulmonary fibrosis in the era of stratified medicine. Thorax 71:1154-1160
Ulrich, Victoria; Gelber, Shari E; Vukelic, Milena et al. (2016) ApoE Receptor 2 Mediation of Trophoblast Dysfunction and Pregnancy Complications Induced by Antiphospholipid Antibodies in Mice. Arthritis Rheumatol 68:730-739
Chambliss, Ken L; Barrera, Jose; Umetani, Michihisa et al. (2016) Nonnuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice. Endocrinology 157:3731-3741

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