This proposal will fund the NHLBI CVD Epi Training Program in Behavior, the Environment, and Global Health, critically important scientific disciplines that remain under-represented in NHLBI training. This Program will train 3 pre-doctoral and 4 post-doctoral trainees each year in the rich academic environment of the Harvard School of Public Health and affiliated institutions locally and worldwide, bringing together outstanding faculty Mentors to provide integrated and interdisciplinary experiences and collaborative interactions, specialized curriculum with core and elective coursework, nondidactic practical career training, individual candidate training plans, and ongoing Program evaluation. Cutting-edge didactic training and mentoring will create a new generation of highly skilled and enthusiastic investigators to study the impact of behavioral and environmental risk factors on cardiometabolic diseases;to elucidate the cultural norms, genomic variation, and biologic and sociologic pathways that modify these risk factors;and to understand and utilize the full set of epidemiologic, interventional, environmental, and policy tools to design, implement, and evaluate the most effective individualized, community, and policy interventions to reduce impact of harmful risk factors, facilitate expansion of protective behavioral and environmental factors, and attenuate or reverse the alarming global trends in cardiometabolic diseases. Training will include modern methodological and analytical techniques required to study the intersections of cardiometabolic diseases with Behavior, including observational epidemiology and interventions in adulthood, adolescence, and early life;the Environment, including airborne and environmental toxins, social risks, and physical (built) environment;and Global Health, including observational epidemiology, demography, comparative risk assessment, and controlled interventions at both individual and community levels. This Training Program adds considerable strength and depth to the NHLBI's commitment to understanding the behavioral and environmental determinants, preventive measures, and treatments of cardiovascular and metabolic diseases in both developed and developing nations.

Public Health Relevance

Training a new generation of investigators to understand how behavioral and environmental risk factors impact cardiovascular and metabolic diseases, and how to cost-effectively and sustain ably modify these factors, is among the most important scientific tasks of our time. These are global challenges, as changing behaviors and environmental risks are rapidly increasing cardiovascular and metabolic diseases worldwide and widespread use of costly new drug- and device-related treatments may not be practical or cost-effective.

Agency
National Institute of Health (NIH)
Type
Institutional National Research Service Award (T32)
Project #
2T32HL098048-06A1
Application #
8742916
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Stoney, Catherine
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Harvard University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02115
Yakoob, Mohammad Y; Micha, Renata; Khatibzadeh, Shahab et al. (2016) Impact of Dietary and Metabolic Risk Factors on Cardiovascular and Diabetes Mortality in South Asia: Analysis From the 2010 Global Burden of Disease Study. Am J Public Health 106:2113-2125
Adjaye-Gbewonyo, Kafui; Avendano, Mauricio; Subramanian, S V et al. (2016) Income inequality and depressive symptoms in South Africa: A longitudinal analysis of the National Income Dynamics Study. Health Place 42:37-46
Crous-Bou, Marta; Harrington, Laura B; Kabrhel, Christopher (2016) Environmental and Genetic Risk Factors Associated with Venous Thromboembolism. Semin Thromb Hemost 42:808-820
Barber, Sharrelle; Hickson, DeMarc A; Kawachi, Ichiro et al. (2016) Double-jeopardy: The joint impact of neighborhood disadvantage and low social cohesion on cumulative risk of disease among African American men and women in the Jackson Heart Study. Soc Sci Med 153:107-15
James, Peter; Jankowska, Marta; Marx, Christine et al. (2016) "Spatial Energetics": Integrating Data From GPS, Accelerometry, and GIS to Address Obesity and Inactivity. Am J Prev Med 51:792-800
Tucker-Seeley, Reginald D; Bezold, Carla P; James, Peter et al. (2016) Retail Pharmacy Policy to End the Sale of Tobacco Products: What Is the Impact on Disparity in Neighborhood Density of Tobacco Outlets? Cancer Epidemiol Biomarkers Prev 25:1305-10
Barber, Sharrelle; Hickson, DeMarc A; Kawachi, Ichiro et al. (2016) Neighborhood Disadvantage and Cumulative Biological Risk Among a Socioeconomically Diverse Sample of African American Adults: An Examination in the Jackson Heart Study. J Racial Ethn Health Disparities 3:444-56
Harrington, Laura B; Marck, Brett T; Wiggins, Kerri L et al. (2016) Cross-sectional association of endogenous steroid hormone, sex hormone-binding globulin, and precursor steroid levels with hemostatic factor levels in postmenopausal women. J Thromb Haemost :
Harrington, Laura B; Weiss, Noel S; Wiggins, Kerri L et al. (2016) Prior hysterectomy and oophorectomy and incident venous thrombosis risk among postmenopausal women: a population-based, case-control study. Menopause 23:143-9
Kioumourtzoglou, Marianthi-Anna; Schwartz, Joel; James, Peter et al. (2016) PM2.5 and Mortality in 207 US Cities: Modification by Temperature and City Characteristics. Epidemiology 27:221-7

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