As imaging technology and molecular medicine advances, more complex questions arise often requiring the convergence of perspectives from multiple disciplines. The future of cardiovascular imaging will most likely be practiced by integrated multidisciplinary teams with diverse expertise. The goal of this research training program is to provide multi-disciplinary post-doctoral multi-modality training in molecular and translational cardiovascular imaging for highly qualified fellows holding either a MD or/and PhD, in preparation for academic careers as independent investigators in the highly clinically relevant field of cardiovascular imaging. Applications will be encouraged from both clinical and basic science departments, with particular attention to the recruitment of minority, disabled, and disadvantaged candidates. We anticipate enrollment of 4 post-doctoral applicants each year into the programs, with an equal balance between physicians and scientists. Post-doctoral fellowship training will be 2-3 years in duration. There will be three primary research focuses in the post-doctoral training, 1) cardiovascular molecular imaging, 2) cardiovascular imaging technologies and analyses, and 3) translational cardiovascular imaging. The primary faculty for this program are from the Yale School of Engineering and Applied Sciences and from multiple departments within the Yale School of Medicine, including: Internal Medicine (Section of Cardiovascular Medicine), Diagnostic Radiology, Surgery, Anesthesiology, and Therapeutic Radiology. The sponsoring faculty was selected based on extramural support, research productivity, and commitment to multi-disciplinary training. Trainee progress will be monitored by individual mentors, the trainee's advisory committee, and the Program Directors. Drs. Sinusas and Duncan will co-manage the program to assure a balance and integration of the training of applicants in the relevant clinical and engineering sciences.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL098069-05
Application #
8725724
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Wang, Wayne C
Project Start
2010-09-21
Project End
2015-08-31
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New Haven
State
CT
Country
United States
Zip Code
06510
Chan, Chung; Liu, Hui; Grobshtein, Yariv et al. (2016) Noise suppressed partial volume correction for cardiac SPECT/CT. Med Phys 43:5225
Stacy, M R; Qiu, M; Papademetris, X et al. (2016) Application of BOLD Magnetic Resonance Imaging for Evaluating Regional Volumetric Foot Tissue Oxygenation: A Feasibility Study in Healthy Volunteers. Eur J Vasc Endovasc Surg 51:743-9
Stacy, Mitchel R; Sinusas, Albert J (2016) Novel Applications of Radionuclide Imaging in Peripheral Vascular Disease. Cardiol Clin 34:167-77
Stendahl, John C; Sinusas, Albert J (2015) Nanoparticles for Cardiovascular Imaging and Therapeutic Delivery, Part 2: Radiolabeled Probes. J Nucl Med 56:1637-41
Liu, Hui; Chan, Chung; Grobshtein, Yariv et al. (2015) Anatomical-based partial volume correction for low-dose dedicated cardiac SPECT/CT. Phys Med Biol 60:6751-73
Compas, Colin B; Wong, Emily Y; Huang, Xiaojie et al. (2015) Correction to ""Radial Basis Functions for Combining Shape and Speckle Tracking in 4D Echocardiography"". IEEE Trans Med Imaging 34:690
Stendahl, John C; Sinusas, Albert J (2015) Nanoparticles for Cardiovascular Imaging and Therapeutic Delivery, Part 1: Compositions and Features. J Nucl Med 56:1469-75
Khosravi, Ramak; Miller, Kristin S; Best, Cameron A et al. (2015) Biomechanical diversity despite mechanobiological stability in tissue engineered vascular grafts two years post-implantation. Tissue Eng Part A 21:1529-38
Stacy, Mitchel R; Paeng, Jin Chul; Sinusas, Albert J (2015) The role of molecular imaging in the evaluation of myocardial and peripheral angiogenesis. Ann Nucl Med 29:217-23
Miller, Kristin S; Khosravi, Ramak; Breuer, Christopher K et al. (2015) A hypothesis-driven parametric study of effects of polymeric scaffold properties on tissue engineered neovessel formation. Acta Biomater 11:283-94

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