This renewal application is to support a Postdoctoral Program in Systems and Behavioral Neuroscience that will prepare trainees for independent professional careers in the brain sciences. Trainees will learn how to critically evaluate the scientific literature, to identify fruitful lines of inquiry, to design incisive, interpretable 3xperiments, and to apply cutting-edge methods. In this renewal, our Program retains its longstanding strength in modern, multidisciplinary approaches for the study of neural processes underlying behavior, ncluding perception, orientation and communication;synaptic plasticity, learning and memory;and oriented motor actions. We offer training in the full spectrum of essential, state-of-the-art techniques in the neurosciences. These include noninvasive functional MRI, robotics and neuroprosthetics, manipulations of neuronal genes, sophisticated recording and imaging methods, and functional proteomics. The breadth of our training program is enhanced by the Brown Institute for Brain Science a network that links more that 90 acuity from eleven departments and successfully integrates techniques from applied mathematics, computer science, and biomedical engineering with the biological and behavioral neurosciences. This grant supports candidates early in their postdoctoral studies who display significant promise for a successful career in research. Beyond developing excellence in bench science, the Program provides venues for trainees to develop ancillary skills important for career development, including opportunities to mentor graduate and undergraduate students in research, to craft successful fellowship and grant proposals, to attend journal clubs and courses, and to hone their presentation skills. Retreats and seminar series offer trainees other opportunities to learn about groundbreaking science and interact with leaders in the field. Career development workshops are given on topics including responsible conduct of research, time management, women in science, scientific writing and nonacademic career tracks. Funds are requested for five years of support for four postdoctoral trainees.
The training provided in this Program will contribute to our understanding and treatment of a wide range of psychiatric and neurological diseases in two direct ways. First, trainees will participate in ongoing brain and behavioral neuroscience research programs. Second, the Program will prepare trainees for their independent careers in these fields.
|Moher, Jeff; Song, Joo-Hyun (2014) Perceptual decision processes flexibly adapt to avoid change-of-mind motor costs. J Vis 14:1|
|Polter, Abigail M; Bishop, Rachel A; Briand, Lisa A et al. (2014) Poststress block of kappa opioid receptors rescues long-term potentiation of inhibitory synapses and prevents reinstatement of cocaine seeking. Biol Psychiatry 76:785-93|
|Moher, Jeff; Song, Joo-Hyun (2014) Target selection bias transfers across different response actions. J Exp Psychol Hum Percept Perform 40:1117-30|
|Collins, Anne G E; Cavanagh, James F; Frank, Michael J (2014) Human EEG uncovers latent generalizable rule structure during learning. J Neurosci 34:4677-85|
|Ouyang, Qing; Lizarraga, Sofia B; Schmidt, Michael et al. (2013) Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. Neuron 80:97-112|
|Moher, Jeff; Song, Joo-Hyun (2013) Context-dependent sequential effects of target selection for action. J Vis 13:|
|Graziane, Nicholas M; Polter, Abigail M; Briand, Lisa A et al. (2013) Kappa opioid receptors regulate stress-induced cocaine seeking and synaptic plasticity. Neuron 77:942-54|
|Cavanagh, James F; Eisenberg, Ian; Guitart-Masip, Marc et al. (2013) Frontal theta overrides pavlovian learning biases. J Neurosci 33:8541-8|
|Furtak, Sharon C; Cho, Christine E; Kerr, Kristin M et al. (2009) The Floor Projection Maze: A novel behavioral apparatus for presenting visual stimuli to rats. J Neurosci Methods 181:82-8|
|Isayama, Tomoki; O'Brien, Brendan J; Ugalde, Irma et al. (2009) Morphology of retinal ganglion cells in the ferret (Mustela putorius furo). J Comp Neurol 517:459-80|
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