This application requests five further years of support for an Institutional National Research Service Award to cover multidisciplinary training in Psychiatric, Behavioral and Statistical Genetics. We request support for three pre-doctoral and three postdoctoral students for primary training in: i) statistical, quantitative, behavioral and molecular genetics~ ii) psychiatric nosology~ iii) neuroimaging genetics and neurobiology~ iv) clinical psychology~ iv) biostatistics. In addition to specializing in one of these areas, trainee will be exposed to all others and encouraged to study at least one other with sufficient detail to broaden their scope for future career development and interdisciplinary research. Training will usually be 4 years in duration for pre-doctoral and 2-3 years for postdoctoral students. Applications are expected from a wide variety of disciplines, including medicine, psychiatry, psychology, biostatistics, neuroscience, molecular genetics and biology. Trainees are housed in the Virginia Institute for Psychiatric and Behavioral Genetics at Virginia Commonwealth University, a modern custom-built facility with private offices, state-of-the-art computational facilities and integrated molecular genetics and experimental laboratories. Major strengths of the program include: i) broad expertise of faculty in psychiatry, psychology, genetics, neuroscience and statistics~ ii) highly productive research environment with well-funded faculty who are among the most highly cited researchers in the field~ iii) extensive experience and excellent track record of faculty in training at this level~ iv) potential for trainees to take pat in active data collection and data analysis projects~ v) access to large genetically informative datasets collected at VCU and elsewhere~ vi) direct access to genome sequencing, experimental study and neuroimaging facilities~ vii) pairing with clinical psychiatrist to attend rounds~ and viii) face-to-face instruction in responsible conduct of research from a leading author and instructor in this field.

Public Health Relevance

There is a shortage of suitably trained researchers who have skills in both statistical or molecular genetics and psychiatric epidemiology. Such individuals ar needed to increase our understanding of genetic and environmental risks for psychiatric disorders, so that better prevention and treatments can be developed. This training grant will educate three pre-doctoral and three postdoctoral trainees in psychiatric, behavioral, statistical and molecular genetics and neuroscience.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Institutional National Research Service Award (T32)
Project #
2T32MH020030-16
Application #
8667069
Study Section
Special Emphasis Panel (ZMH1)
Program Officer
Desmond, Nancy L
Project Start
1999-07-01
Project End
2019-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
16
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Rappaport, Lance M; Moskowitz, D S; D'Antono, Bianca (2017) Depression symptoms moderate the association between emotion and communal behavior. J Couns Psychol 64:269-279
Peterson, Roseann E; Edwards, Alexis C; Bacanu, Silviu-Alin et al. (2017) The utility of empirically assigning ancestry groups in cross-population genetic studies of addiction. Am J Addict 26:494-501
Lind, Mackenzie J; Hawn, Sage E; Sheerin, Christina M et al. (2017) An examination of the etiologic overlap between the genetic and environmental influences on insomnia and common psychopathology. Depress Anxiety 34:453-462
Moore, Ashlee A; Sawyers, Chelsea; Adkins, Daniel E et al. (2017) Opportunities for an enhanced integration of neuroscience and genomics. Brain Imaging Behav :
Sheerin, Christina M; Lind, Mackenzie J; Bountress, Kaitlin et al. (2017) The Genetics and Epigenetics of PTSD: Overview, Recent Advances, and Future Directions. Curr Opin Psychol 14:5-11
Savage, Jeanne E; Sawyers, Chelsea; Roberson-Nay, Roxann et al. (2017) The genetics of anxiety-related negative valence system traits. Am J Med Genet B Neuropsychiatr Genet 174:156-177
Moore, Ashlee A; Carney, Dever; Moroney, Elizabeth et al. (2017) The Inventory of Callous-Unemotional Traits (ICU) in Children: Reliability and Heritability. Behav Genet 47:141-151
Moore, Ashlee A; Overstreet, Cassie; Kendler, Kenneth S et al. (2017) Potentially traumatic events, personality, and risky sexual behavior in undergraduate college students. Psychol Trauma 9:105-112
Lind, Mackenzie J; Baylor, Allison; Overstreet, Cassie M et al. (2017) Relationships between potentially traumatic events, sleep disturbances, and symptoms of PTSD and alcohol use disorder in a young adult sample. Sleep Med 34:141-147
Cai, Na; Bigdeli, Tim B; Kretzschmar, Warren W et al. (2017) 11,670 whole-genome sequences representative of the Han Chinese population from the CONVERGE project. Sci Data 4:170011

Showing the most recent 10 out of 157 publications