This application requests five further years of support for an Institutional National Research Service Award to cover multidisciplinary training in Psychiatric, Behavioral and Statistical Genetics. We request support for three pre-doctoral and three postdoctoral students for primary training in: i) statistical, quantitative, behavioral and molecular genetics~ ii) psychiatric nosology~ iii) neuroimaging genetics and neurobiology~ iv) clinical psychology~ iv) biostatistics. In addition to specializing in one of these areas, trainee will be exposed to all others and encouraged to study at least one other with sufficient detail to broaden their scope for future career development and interdisciplinary research. Training will usually be 4 years in duration for pre-doctoral and 2-3 years for postdoctoral students. Applications are expected from a wide variety of disciplines, including medicine, psychiatry, psychology, biostatistics, neuroscience, molecular genetics and biology. Trainees are housed in the Virginia Institute for Psychiatric and Behavioral Genetics at Virginia Commonwealth University, a modern custom-built facility with private offices, state-of-the-art computational facilities and integrated molecular genetics and experimental laboratories. Major strengths of the program include: i) broad expertise of faculty in psychiatry, psychology, genetics, neuroscience and statistics~ ii) highly productive research environment with well-funded faculty who are among the most highly cited researchers in the field~ iii) extensive experience and excellent track record of faculty in training at this level~ iv) potential for trainees to take pat in active data collection and data analysis projects~ v) access to large genetically informative datasets collected at VCU and elsewhere~ vi) direct access to genome sequencing, experimental study and neuroimaging facilities~ vii) pairing with clinical psychiatrist to attend rounds~ and viii) face-to-face instruction in responsible conduct of research from a leading author and instructor in this field.
There is a shortage of suitably trained researchers who have skills in both statistical or molecular genetics and psychiatric epidemiology. Such individuals ar needed to increase our understanding of genetic and environmental risks for psychiatric disorders, so that better prevention and treatments can be developed. This training grant will educate three pre-doctoral and three postdoctoral trainees in psychiatric, behavioral, statistical and molecular genetics and neuroscience.
|Salvatore, Jessica E; Thomas, Nathaniel S; Cho, Seung Bin et al. (2016) The role of romantic relationship status in pathways of risk for emerging adult alcohol use. Psychol Addict Behav 30:335-44|
|Edwards, Alexis C; Bigdeli, Tim B; Docherty, Anna R et al. (2016) Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes. Schizophr Bull 42:279-87|
|Moore, Ashlee A; Overstreet, Cassie; Kendler, Kenneth S et al. (2016) Potentially Traumatic Events, Personality, and Risky Sexual Behavior in Undergraduate College Students. Psychol Trauma :|
|Sheerin, Christina M; Kozak, Andrea T; Hale, Andrew C et al. (2016) The effect of D-cycloserine on social anxiety treatment using a behavioral outcome measure and a post-session administration strategy. Behav Anal (Wash D C) 16:123-134|
|Docherty, A R; Moscati, A; Peterson, R et al. (2016) SNP-based heritability estimates of the personality dimensions and polygenic prediction of both neuroticism and major depression: findings from CONVERGE. Transl Psychiatry 6:e926|
|Berenz, Erin C; Cho, Seung Bin; Overstreet, Cassie et al. (2016) Longitudinal investigation of interpersonal trauma exposure and alcohol use trajectories. Addict Behav 53:67-73|
|Putman, A H; Wolen, A R; Harenza, J L et al. (2016) Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains. Genes Brain Behav 15:367-81|
|Li, James J; Reise, Steven P; Chronis-Tuscano, Andrea et al. (2016) Item Response Theory Analysis of ADHD Symptoms in Children With and Without ADHD. Assessment 23:655-671|
|Savage, Jeanne E; Kaprio, Jaakko; Korhonen, Tellervo et al. (2016) The effects of social anxiety on alcohol and cigarette use across adolescence: Results from a longitudinal twin study in Finland. Psychol Addict Behav 30:462-74|
|Ware, Jennifer J; Chen, Xiangning; Vink, Jacqueline et al. (2016) Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2. Sci Rep 6:20092|
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