This is a revised application for a renewed Institutional National Research Service Award to support two- and three-year postdoctoral and one-year predoctoral Traineeships in Translational Developmental Neuroscience Research at the New York University Department of Child &Adolescent Psychiatry, aka Child Study Center (CSC) and the Nathan Kline Institute for Psychiatric Research (NKI) which have been configured for this express purpose. The new field of Translational Developmental Neuroscience will facilitate the integration of a wide range of disciplines to alleviate the lifelong burden of mental illness by focusing on the early developmental stages. Predoctoral trainees will be medical students who choose to extend their education by one year to conduct mentored Translational Developmental Neuroscience research working directly with the Program Director or the Co-Director in their labs. Post-doctoral trainees will be drawn from Child and Adolescent Psychiatry, Child Psychology, Pediatric Neurology, Developmental and Behavioral Pediatrics, Cognitive Neuroscience, Medical Physics, Systems Neuroscience, Neurophysiology, Applied Mathematics, and Computer Science. Available resources include expertise in pharmacological and psychosocial intervention and prevention trials, functional, structural and chemical neuroimaging, longitudinal studies, assessment of child/adolescent psychopathology, and affiliated faculties with expertise that extends from neurophysiology, basic developmental neuroscience to applied mathematics, biostatistics, biomedical engineering and biomedical physics. Research fellows work closely with two primary co-mentors to facilitate the development of independent translational research careers that will extend from the bench-to-bedside or from bedside-to-community. Trainees benefit from highly diverse patient populations at Bellevue Hospital Center, CSC, and the Rockland Children's Psychiatric Center. The overall goals of the program will continue to be to provide excellent research training focused on child mental health problems, and to advance trainees to productive academic research careers in the new discipline of Translational Developmental Neuroscience.

Public Health Relevance

Medicine is advancing rapidly in many areas, but the science of the brain continues to lag behind, especially when addressing the emotional and behavioral problems of children and adolescents. We propose to train a new type of scientist who will bring a wealth of perspectives to these important challenges by providing individualized mentoring to junior scientists who have completed their doctoral and clinical studies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Institutional National Research Service Award (T32)
Project #
5T32MH067763-08
Application #
8102998
Study Section
Special Emphasis Panel (ZMH1-ERB-C (01))
Program Officer
Churchill, James D
Project Start
2003-07-01
Project End
2014-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
8
Fiscal Year
2011
Total Cost
$366,504
Indirect Cost
Name
New York University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
García Murillo, Lourdes; Ramos-Olazagasti, María A; Klein, Rachel G et al. (2018) Correlates of nicotine dependence in men with childhood attention-deficit/hyperactivity disorder: a 33-year follow-up. Atten Defic Hyperact Disord :
Ramos-Olazagasti, María A; Castellanos, Francisco Xavier; Mannuzza, Salvatore et al. (2018) Predicting the Adult Functional Outcomes of Boys With ADHD 33 Years Later. J Am Acad Child Adolesc Psychiatry 57:571-582.e1
Hoogman, Martine; Bralten, Janita; Hibar, Derrek P et al. (2017) Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis. Lancet Psychiatry 4:310-319
Yoncheva, Yuliya N; Hardy, Kristina K; Lurie, Daniel J et al. (2017) Computerized cognitive training for children with neurofibromatosis type 1: A pilot resting-state fMRI study. Psychiatry Res Neuroimaging 266:53-58
García Murillo, Lourdes; Ramos-Olazagasti, Maria A; Mannuzza, Salvatore et al. (2016) Childhood Attention-Deficit/Hyperactivity Disorder and Homelessness: A 33-Year Follow-Up Study. J Am Acad Child Adolesc Psychiatry 55:931-936
Yoncheva, Yuliya N; Somandepalli, Krishna; Reiss, Philip T et al. (2016) Mode of Anisotropy Reveals Global Diffusion Alterations in Attention-Deficit/Hyperactivity Disorder. J Am Acad Child Adolesc Psychiatry 55:137-45
Baroni, Argelinda; Castellanos, F Xavier (2015) Neuroanatomic and cognitive abnormalities in attention-deficit/hyperactivity disorder in the era of 'high definition' neuroimaging. Curr Opin Neurobiol 30:1-8
Sadrian, Benjamin; Wilson, Donald A (2015) Optogenetic Stimulation of Lateral Amygdala Input to Posterior Piriform Cortex Modulates Single-Unit and Ensemble Odor Processing. Front Neural Circuits 9:81
Yoncheva, Yuliya N; Wise, Jessica; McCandliss, Bruce (2015) Hemispheric specialization for visual words is shaped by attention to sublexical units during initial learning. Brain Lang 145-146:23-33
Sadrian, B; Lopez-Guzman, M; Wilson, D A et al. (2014) Distinct neurobehavioral dysfunction based on the timing of developmental binge-like alcohol exposure. Neuroscience 280:204-19

Showing the most recent 10 out of 47 publications