New technologies have enabled amazing access to neural processes at multiple resolutions of time and space. However, the data analyses necessary to answer the scientific questions often depend on computational techniques that are unique to the experiment and may have to be modified (or even developed anew) for each specific experiment. These are not techniques that can be learned in a single class, but rather ways of thinking about problems that must be incorporated into each experiment and each analysis. Fundamentally, the data are being collected, but the field is not getting the full value of the collected data; students need additional training in order to successfully extract the complete information present in their experiments. Students need to understand both the complexities and limitations within experimental paradigms and also the complexities and limitations within computational analyses that can be applied to those paradigms. More importantly, if a student is going to develop his or her own analyses, the student needs a deep understanding of how to define and derive the appropriate control analyses. Ensuring the rigor of the experimental design and the subsequent analyses is particularly difficult for these types of data. We propose to build a comprehensive training program for both predoctoral graduate students and early-stage postdocs, to teach them how to integrate computational analyses and techniques to achieve scientific breakthroughs in neuroscience. This training will place these students in a very strong position for furthering their scientific careers. Furthermore, the training program will also help support, maintain, and improve the strong interdisciplinary community in computational, experimental, and clinical neuroscience that already exists within the University of Minnesota.

Public Health Relevance

New technologies have enabled amazing access to neural processes at multiple resolutions of time and space; however, these new technologies also require new and complex computational analyses. Fundamentally, the data are being collected, but the field is not getting the full value of the collected data; students need additional training in order to successfully extract the full information present in neuroscience experiments. The proposed program will train predoctoral graduate students and postdocs to use and develop computational methods to contribute to both the fundamental science that provides the basis for our understanding of neuroscience and to the clinical science that translates that fundamental understanding into improvements in human health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Institutional National Research Service Award (T32)
Project #
5T32MH115886-02
Application #
9707925
Study Section
Special Emphasis Panel (ZMH1)
Program Officer
Van'T Veer, Ashlee V
Project Start
2018-07-01
Project End
2023-06-30
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
2
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Neurosciences
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455