This is a proposal for continuation of support for a training program in Neuroepidemiology. To our knowledge, it is the only NIH-funded neuroepidemiology training program in the United States. The goal of the program is to prepare neurologists and other research scientists for research careers in the epidemiology of neurologic disorders. Since its inception, the program has trained neurologists and neuroscientists who are now assistant professors, associate professors, professors or career research scientists at the NIH and elsewhere. The program, which has completed its 28th year of funding, has capitalized upon the strengths of the Department of Neurology (College of Physicians and Surgeons), the Departments of Epidemiology and Biostatistics (Mailman School of Public Health), and the inter-disciplinary structure of the Gertrude H. Sergievsky Center, all at Columbia University Medical Center. The program provides stimulating training in a research environment for developing neuroscientists who wish to use epidemiologic methods to study diseases of the nervous system, and have as a career goal, a research or academic position. The structured, didactic training provided by the curriculum at the Mailman School of Public Health, combined with the opportunity to participate in and expand upon ongoing epidemiologic studies of neurologic disease conducted by program faculty, provide trainees with an optimal training for academic positions. Trainees will have the opportunity to work on large ongoing epidemiological studies utilizing multiple different study designs, including case-control and prospective cohort studies such as the Northern Manhattan Study, the Washington-Heights Inwood Study of Aging, Environmental Epidemiology of Essential Tremor Study, and Genetic Epidemiology of Seizure Disorders study. Our past trainees have successfully competed for independent funding from the NIH and other sources. We are requesting support for four MD/DO neurologists or appropriate postdoctoral neuroscientist (PhD or equivalent) each year for five years. All trainees will spend two years in the program, during which time sequenced didactic course work in epidemiology and biostatistics will be integrated with increasingly independent research activity. A degree (MS in epidemiology from Mailman School of Public Health) is the recommended course for most trainees.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZNS1-SRB-P (47))
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Korn, Stephen J
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Columbia University (N.Y.)
Schools of Medicine
New York
United States
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Benito-León, Julián; Louis, Elan D; Villarejo-Galende, Alberto et al. (2014) Long sleep duration in elders without dementia increases risk of dementia mortality (NEDICES). Neurology 83:1530-7
Sultan, Sally; Schupf, Nicole; Dowling, Michael et al. (2014) Predictors of cholesterol and lipoprotein(a) testing in children with arterial ischemic stroke. J Stroke Cerebrovasc Dis 23:2405-13
Romero, Juan Pablo; Benito-León, Julián; Louis, Elan D et al. (2014) Under reporting of dementia deaths on death certificates: a systematic review of population-based cohort studies. J Alzheimers Dis 41:213-21
Boyd, Clara D; Tierney, Michael; Wassermann, Eric M et al. (2014) Visuoperception test predicts pathologic diagnosis of Alzheimer disease in corticobasal syndrome. Neurology 83:510-9
Louis, Elan D; Lee, Michelle; Cortés, Etty et al. (2014) Matching asymmetry of tremor with asymmetry of postmortem cerebellar hemispheric changes in essential tremor. Cerebellum 13:462-70
Benito-León, Julián; Romero, Juan Pablo; Louis, Elan D et al. (2014) Faster cognitive decline in elders without dementia and decreased risk of cancer mortality: NEDICES Study. Neurology 82:1441-8
Sultan, Sally M; Schupf, Nicole; Dowling, Michael M et al. (2014) Review of lipid and lipoprotein(a) abnormalities in childhood arterial ischemic stroke. Int J Stroke 9:79-87
Mez, Jesse; Cosentino, Stephanie; Brickman, Adam M et al. (2013) Dysexecutive versus amnestic Alzheimer disease subgroups: analysis of demographic, genetic, and vascular factors. Alzheimer Dis Assoc Disord 27:218-25
Mez, Jesse; Stern, Robert A; McKee, Ann C (2013) Chronic traumatic encephalopathy: where are we and where are we going? Curr Neurol Neurosci Rep 13:407
Mez, Jesse; Cosentino, Stephanie; Brickman, Adam M et al. (2013) Different demographic, genetic, and longitudinal traits in language versus memory Alzheimer's subgroups. J Alzheimers Dis 37:137-46

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