This is a proposal to continue a long-standing postdoctoral training program at Brandeis University. This program is designed to enhance the quantitative skills of a diverse group of investigators involved in solving the problems posed by myriad disorders of the nervous system. To understand neurological disorders and develop new therapies a cadre of outstanding investigators with strong quantitative skills working in research intensive academic institutions, in industry, and in other capacities, is required. Trainees with PhDs in mathematics, physics, engineering, and computer science will be brought into neuroscience through a program of mentored laboratory research and course work. Trainees with PhDs in the biological sciences will enter a program of mentored laboratory research and receive additional training in applying quantitative methods to understand basic and translational work in neuroscience. All trainees will participate in seminars, journal clubs, and will obtain mentoring experience and training in the responsible conduct of science. Efforts to increase the diversity of the scientific work force are described.
. Brain disorders are responsible for significant pain and suffering and economic cost. To facilitate the understanding of brain function and the development of new therapies for brain disorders, this program will produce a generation of quantitatively strong brain scientists.
|Payne, Lisa; Sekuler, Robert (2014) The importance of ignoring: Alpha oscillations protect selectivity. Curr Dir Psychol Sci 23:171-177|
|Rosado, Michelle; Barber, Cynthia F; Berciu, Cristina et al. (2014) Critical roles for multiple formins during cardiac myofibril development and repair. Mol Biol Cell 25:811-27|
|Ghiretti, Amy E; Moore, Anna R; Brenner, Rebecca G et al. (2014) Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo. J Neurosci 34:392-407|
|Shang, Yuhua; Donelson, Nathan C; Vecsey, Christopher G et al. (2013) Short neuropeptide F is a sleep-promoting inhibitory modulator. Neuron 80:171-83|
|Chaudhry, Faisal; Breitsprecher, Dennis; Little, Kristin et al. (2013) Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin. Mol Biol Cell 24:31-41|
|Moore, Anna R; Ghiretti, Amy E; Paradis, Suzanne (2013) A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexity. PLoS One 8:e74751|
|Kuzirian, Marissa S; Moore, Anna R; Staudenmaier, Emily K et al. (2013) The class 4 semaphorin Sema4D promotes the rapid assembly of GABAergic synapses in rodent hippocampus. J Neurosci 33:8961-73|
|Lash, Amanda; Rogers, Chad S; Zoller, Amy et al. (2013) Expectation and entropy in spoken word recognition: effects of age and hearing acuity. Exp Aging Res 39:235-53|
|Payne, Lisa; Guillory, Sylvia; Sekuler, Robert (2013) Attention-modulated alpha-band oscillations protect against intrusion of irrelevant information. J Cogn Neurosci 25:1463-76|
|Beadle, Janelle N; Yoon, Carolyn; Gutchess, Angela H (2012) Age-related neural differences in affiliation and isolation. Cogn Affect Behav Neurosci 12:269-79|
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