Continuing support is requested for a broadly based predoctoral training program in the neurosciences at the University of Cincinnati. The training program is intended to support a total of 4 students over their first 2 years of graduate education. The goals of the program are to 1) recruit top-quality students who show outstanding potential for a career in the neurosciences; 2) provide high-quality instruction in the fundamentals of neuroscience and in the ethical conduct of research; 3) provide students research experience in top laboratories featuring innovative and state-of-art models and approaches; 4) create a vibrant neuroscience community through seminars, special symposia, journal clubs and activities to promote cohesiveness; 5) prepare students for careers in the neurosciences through instruction in academic survival skills, instruction in teaching, yearly career workshops, and thoughtful mentoring; and 6) create a culture of sharing through a variety of outreach activities. In response to a strong endorsement of the program in our recent review, the University of Cincinnati has made substantial financial commitments to the neuroscience community, providing new funds for recruitment of new faculty and programmatic enhancement. These additional funds supplement the already strong level of financial and administrative support from the College of Medicine. The training faculty are active and well-funded, and share a strong commitment to graduate education. Efforts of the institution and program faculty have resulted in maintenance of a strong applicant pool from top universities and colleges. Our trainees consistently land postdoctoral positions at prominent institutions, and go on to successful careers in academia, industry and scientific policy, attesting to the strength and vitality of the program. New initiatives include recruitment of additional faculty across our broad neuroscience base; creation of a dynamic neuroscience curriculum responsive to the changing needs of our students; using individual development plans to ensure strong mentoring of all students; and providing trainees ample opportunity to understand the diversity of neuroscience career options. We anticipate that the graduates of our program will continue to play a major role in future research efforts to 1) discover mechanisms underlying pathology of the nervous system and 2) develop new strategies to treat or prevent disease.

Public Health Relevance

Neuroscience research is critical for development of strategies to prevent, diagnose and treat diseases of the nervous system. This broadly based training program is designed to provide the next generation of researchers with a solid foundation in the fundamentals of neuroscience and strong, cutting-edge research training in basic and translational neuroscience.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
2T32NS007453-16
Application #
9086172
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Weigand, Letitia Alexis
Project Start
1997-09-30
Project End
2021-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
16
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Psychiatry
Type
Schools of Medicine
DUNS #
041064767
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Smith, Brittany L; Lyons, Carey E; Correa, Fernanda Guilhaume et al. (2017) Behavioral and physiological consequences of enrichment loss in rats. Psychoneuroendocrinology 77:37-46
Snedeker, John; Schock, Elizabeth N; Struve, Jamie N et al. (2017) Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development. PLoS One 12:e0173258
Jensen, Victoria N; Romer, Shannon H; Turner, Sarah M et al. (2017) Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease. J Vis Exp :
Nguyen, Elizabeth T; Streicher, Joshua; Berman, Sarah et al. (2017) A mixed glucocorticoid/mineralocorticoid receptor modulator dampens endocrine and hippocampal stress responsivity in male rats. Physiol Behav 178:82-92
Hosford, Bethany E; Rowley, Shane; Liska, John P et al. (2017) Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression. Sci Rep 7:18015
Schock, Elizabeth N; Struve, Jaime N; Chang, Ching-Fang et al. (2017) A tissue-specific role for intraflagellar transport genes during craniofacial development. PLoS One 12:e0174206
Smith, Brittany L; Schmeltzer, Sarah N; Packard, Benjamin A et al. (2016) Divergent effects of repeated restraint versus chronic variable stress on prefrontal cortical immune status after LPS injection. Brain Behav Immun 57:263-270
Cassella, Sarah N; Hemmerle, Ann M; Lundgren, Kerstin H et al. (2016) Maternal immune activation alters glutamic acid decarboxylase-67 expression in the brains of adult rat offspring. Schizophr Res 171:195-9
Packard, Amy E B; Egan, Ann E; Ulrich-Lai, Yvonne M (2016) HPA Axis Interactions with Behavioral Systems. Compr Physiol 6:1897-1934
Herman, James P; McKlveen, Jessica M; Ghosal, Sriparna et al. (2016) Regulation of the Hypothalamic-Pituitary-Adrenocortical Stress Response. Compr Physiol 6:603-21

Showing the most recent 10 out of 29 publications