This application for a Research Training Grant (T32) is designed to train and mentor clinician scientists from the disciplines of neurology and emergency medicine who will become collaborative leaders in the investigation of the causes and treatment of cerebrovascular disease. We are requesting support for two fellows per year for the first year and four fellowship positions for years 2-5. The mentored two-year program includes course work and extensive hands-on experience in clinical research, close interactions with basic scientists, and unique training in the evaluation and treatment of patients with acute stroke. Our training program is comprised of an extensive network of collaborators and mentors that has resulted in academic productivity among our graduates. Each trainee has a mentoring team of three individuals and chooses a specific research project within the first three to four months of training. Current faculty for this training grant and their focus areas include: Joseph Broderick MD (Director of Training Program - stroke epidemiology, clinical trials, and genetics of stroke), Arthur Pancioli MD (Co-Director of Training Program - clinical trials), Joseph Clark PhD (Director of basic science experience - in vitro and vivo stroke models, cerebrovascular physiology), Daniel Woo MD (Director of neurosonology, genetics of stroke), Thomas Tomsick MD (endovascular therapy, neuroradiology, clinical trials), Brett Kissela MD (stroke epidemiology, stroke outcomes), Edward Jauch MD (proteomics of stroke, clinical trials), Ranjan Deka (molecular and population genetics), Alex Schneider (clinical trials), Dawn Kleindorfer (clinical trials), Christy Holland PhD and George Shaw MD, PhD (cerebrovascular ultrasound), Joel Tsevat (outcomes and quality of life), Kenneth Wagner, PhD (animals models of hemorrhagic and ischemic stroke), Steve Page, PhD (stroke recovery), Scott Holland PhD and Steve Strakowski MD (neuro imaging), Mario Zuccarello MD and Raj Narayan MD (cerebrovascular surgery and thrombolytic stroke), Ronnie Horner PhD (healthcare epidemiologist and outcomes), Rakesh Shukla PhD (biostatistics), and Michael Lehman PhD (circadian rhythms and stroke, Neuroscience Graduate Program). Potential trainees must have completed a residency in neurology or emergency medicine and must demonstrate a commitment to an academic career in cerebrovascular disease. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
5T32NS047996-03
Application #
7442183
Study Section
NST-2 Subcommittee (NST)
Program Officer
Korn, Stephen J
Project Start
2006-07-01
Project End
2011-06-30
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
3
Fiscal Year
2008
Total Cost
$246,588
Indirect Cost
Name
University of Cincinnati
Department
Neurology
Type
Schools of Medicine
DUNS #
041064767
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Katz, Brian S; Adeoye, Opeolu; Sucharew, Heidi et al. (2017) Estimated Impact of Emergency Medical Service Triage of Stroke Patients on Comprehensive Stroke Centers: An Urban Population-Based Study. Stroke 48:2164-2170
Kreitzer, Natalie; Hart, Kimberly; Lindsell, Christopher J et al. (2017) Factors associated with adverse outcomes in patients with traumatic intracranial hemorrhage and Glasgow Coma Scale of 15. Am J Emerg Med 35:875-880
Kircher, Charles; Kreitzer, Natalie; Adeoye, Opeolu (2016) Pre and intrahospital workflow for acute stroke treatment. Curr Opin Neurol 29:14-9
Madsen, Tracy E; Sucharew, Heidi; Katz, Brian et al. (2016) Gender and Time to Arrival among Ischemic Stroke Patients in the Greater Cincinnati/Northern Kentucky Stroke Study. J Stroke Cerebrovasc Dis 25:504-10
Sánchez Fernández, Iván; Abend, Nicholas S; Agadi, Satish et al. (2015) Time from convulsive status epilepticus onset to anticonvulsant administration in children. Neurology 84:2304-11
Demel, Stacie L; Broderick, Joseph P (2015) Basilar Occlusion Syndromes: An Update. Neurohospitalist 5:142-50
Madsen, Tracy E; Khoury, Jane C; Alwell, Kathleen A et al. (2015) Analysis of tissue plasminogen activator eligibility by sex in the Greater Cincinnati/Northern Kentucky Stroke Study. Stroke 46:717-21
Katz, Brian S; McMullan, Jason T; Sucharew, Heidi et al. (2015) Design and validation of a prehospital scale to predict stroke severity: Cincinnati Prehospital Stroke Severity Scale. Stroke 46:1508-12
Kreitzer, Natalie; Lyons, Michael S; Hart, Kim et al. (2014) Repeat neuroimaging of mild traumatic brain-injured patients with acute traumatic intracranial hemorrhage: clinical outcomes and radiographic features. Acad Emerg Med 21:1083-91
Subbian, Vignesh; Meunier, Jason M; Korfhagen, Joseph J et al. (2014) Quantitative assessment of post-concussion syndrome following mild traumatic brain injury using robotic technology. Conf Proc IEEE Eng Med Biol Soc 2014:5353-6

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