The goal of the Neurodegeneration Training Program (NTP) is to provide rigorous pre-doctoral training in various aspects of neurodegeneration and mechanisms of diseases involving neurodegeneration. An outstanding pool of trainees will combine with world-class faculty to investigate a wide range of neurodegeneration-related topics spanning research areas such as protein structure, cell and molecular biology and in vitro and in vivo models of disease. The NTP spans departments, schools and institutions to include multiple departments at Case Western Reserve University, particularly the School of Medicine, and its affiliated institutions, University Hospitals Case Medical Center (UHCMC), The Louis Stokes Cleveland Veteran's Administration Medical Center (VAMC), and the Cleveland Clinic Foundation (CCF, including the Lerner Research Institute). All of these institutions are within walking distance of each other and this rich training environment enjoys very active basic science and clinical activities and state of the art resources to enrich the training of pre- doctoal trainees as they engage in basic and/or translational research in the field of neurodegeneration. Training in the NTP involves NTP course work, formal and informal seminars, an annual retreat, and a research experience resulting in scholarly publications. A unique component of this training program is the inclusion of a required 1 semester, half day per week, mentored experience in a neurodegenerative disease clinic. The combination of didactic and experiential training opportunities afforded by the NTP will provide trainees a solid foundation for a future career in the scientific inquiry of neurodegeneration.
The Neurodegeneration Training Program provides pre-doctoral training to produce future investigators who will drive important biomedical research efforts in neurodegeneration-related areas of clinical importance, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, Prion diseases, Multiple Sclerosis, stroke and other nervous system injury.
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|Courtney, Nicholas A; Ford, Christopher P (2016) Mechanisms of 5-HT1A receptor-mediated transmission in dorsal raphe serotonin neurons. J Physiol 594:953-65|
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|Piccart, Elisabeth; Courtney, Nicholas A; Branch, Sarah Y et al. (2015) Neurotensin Induces Presynaptic Depression of D2 Dopamine Autoreceptor-Mediated Neurotransmission in Midbrain Dopaminergic Neurons. J Neurosci 35:11144-52|
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|Courtney, Nicholas A; Mamaligas, Aphroditi A; Ford, Christopher P (2012) Species differences in somatodendritic dopamine transmission determine D2-autoreceptor-mediated inhibition of ventral tegmental area neuron firing. J Neurosci 32:13520-8|