MIT provides a superb intellectual environment for the comparative veterinary scientist embarking on a career in biomedical research. MIT is recognized internationally for its excellence in both undergraduate and graduate biomedical science education. Capitalizing on these resources, DCM began training veterinarians in laboratory animal medicine in 1982 and has been a recipient of an NIH training grant for the past 24 years. We recognized the urgent need to provide the biomedical research community properly trained veterinarians, particularly those who can effectively work in research and academia. To date, of 48 postdoctoral fellows trained by DCM, all but one are employed in academic or research and development units. The purpose of this proposal is to seek funds to continue postdoctoral training of six veterinary scientists for careers in biomedical research. This will be accomplished in part by providing 1) a strong emphasis in the development of research skills needed for veterinary scientists pursuing a research career, 2) a core curriculum of graduate courses in biomedical sciences, and 3) an intellectual and simulating setting for research in the biomedical sciences. The six postdoctoral trainees will hold DVM degrees and some may have additional advanced degrees as well. The program will consist of three years of in-depth research training with an option to pursue an advanced degree. Participants in the training will include professional and technical personnel within the Division f Comparative Medicine and the Department of Biological Engineering. Two other academic units - the Harvard Medical School and Tufts School of Veterinary Medicine will also be involved. MIT faculty will contribute to the core course work;training in research will be provided with established investigators at MIT and other designated research laboratories at Harvard and Tufts. Research training will emphasize formulation of a significant research project, its design and implementation, critical reviews of pertinent scientific literature, data analysis and statistial evaluation, formal presentation of data at national and international meetings and publications of research in peer reviewed journals. Funds are also requested to support six summer veterinary fellows;these stipends will be used to introduce motivated, bright veterinary students to the field of biomedical research. These students will spend a summer in the same research environment in which our postdoctoral fellows conduct their research.

Public Health Relevance

This proposal requests renewed funding for the Divisions training program for veterinary scientists focusing on biomedical research. We have received funding to train veterinarians for the past 25 years and seek to continue to provide the scientific community with veterinarians with a specialized background in biomedical research and comparative medicine

Agency
National Institute of Health (NIH)
Type
Institutional National Research Service Award (T32)
Project #
5T32OD010978-27
Application #
8670044
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Moro, Manuel H
Project Start
Project End
Budget Start
Budget End
Support Year
27
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Veterinary Sciences
Type
Other Specialized Schools
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02142
Bakthavatchalu, V; Muthupalani, S; Marini, R P et al. (2016) Endocrinopathy and Aging in Ferrets. Vet Pathol 53:349-65
Miller, Cassandra L; Muthupalani, Sureshkumar; Shen, Zeli et al. (2016) Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma. PLoS One 11:e0152940
García, Alexis; Mannion, Anthony; Feng, Yan et al. (2016) Cytotoxic Escherichia coli strains encoding colibactin colonize laboratory mice. Microbes Infect 18:777-786
Esmail, Michael Y; Bacon, Rebecca; Swennes, Alton G et al. (2016) Helicobacter Species Identified in Captive Sooty Mangabeys (Cercocebus atys) with Metastatic Gastric Adenocarcinoma. Helicobacter 21:175-85
Esmail, Michael Y; Qi, Peimin; Connor, Aurora Burds et al. (2016) Generating Chimeric Mice by Using Embryos from Nonsuperovulated BALB/c Mice Compared with Superovulated BALB/c and Albino C57BL/6 Mice. J Am Assoc Lab Anim Sci 55:400-5
Mannion, Anthony; Shen, Zeli; Feng, Yan et al. (2016) Draft Genome Sequences of Five Novel Polyketide Synthetase-Containing Mouse Escherichia coli Strains. Genome Announc 4:
Woods, Stephanie E; Ek, Courtney; Shen, Zeli et al. (2016) Male Syrian Hamsters Experimentally Infected with Helicobacter spp. of the H. bilis Cluster Develop MALT-Associated Gastrointestinal Lymphomas. Helicobacter 21:201-17
Lieberman, Mia T; Wachtman, Lynn M; Marini, Robert P et al. (2016) Spontaneous Cholelithiasis in a Squirrel Monkey (Saimiri sciureus). Comp Med 66:63-7
Ge, Zhongming; Feng, Yan; Woods, Stephanie E et al. (2015) Spatial and temporal colonization dynamics of segmented filamentous bacteria is influenced by gender, age and experimental infection with Helicobacter hepaticus in Swiss Webster mice. Microbes Infect 17:16-22
Burns, Monika; Muthupalani, Sureshkumar; Ge, Zhongming et al. (2015) Helicobacter pylori Infection Induces Anemia, Depletes Serum Iron Storage, and Alters Local Iron-Related and Adult Brain Gene Expression in Male INS-GAS Mice. PLoS One 10:e0142630

Showing the most recent 10 out of 36 publications