The MARC Program at TSU continues from 1980 to date going through continuous evaluation and adjustment. During the last five years (2006-2011) 16 former trainees have received PhD degrees from well known universities including Meharry (2), Vanderbilt (2), Washington U., U. Cincinnati, Michigan State, U. Illinois, U. Nebraska, Emory, S.FL.,U. Ill/Chicago, Yale U., Harvard and MIT. Currently, 21 former trainees are in graduate schools. From this group, four are expected to obtain the PhD degrees in the next two years. Therefore, the TSU program will produce 20 PhDs from 2006-2013 (Please see table 2 in progress report). We think our small program of only 8 to 12 trainees/year in past years has made a significant contribution in increasing the pool of URM biomedical scientists. The GOAL of our MARC U*STAR Program for the next five years will continue to be to produce competitively trained URM students who enter and SUCCESSIVLLY COMPLETE their research doctorates in biomedical/behavioral sciences. This goal aligns well with the mission and strategic goals of the University. To achieve this goal we propose the following OBJECTIVES: 1. To increase the number of U*STAR graduates entering graduate school by 20 % from the current 58% to 70%;2. To maintain or exceed the percentage of MARC graduates receiving PhDs during the next cycle. From 2006-2011, 17 of our former trainees received PhDs (see table 2 in progress report). Based on the number of trainees in the program over those years this is approximately 40% of trainees receiving Ph.Ds. 3. To increase the quantitative and verbal skills of trainees as evidenced, for example, by an average GRE quantitative score increase from 370 (Newly appointed trainees) to 550, a 48% gain. 4. To increase the number of trainee scientific presentations at the professional meetings from 2 per year to 4 per year and publications from 6 per 5 year period to 10 per five year period. 5. To offer challenging curricula including on and off campus research experiences to enhance the competitiveness of our trainees to gain acceptance into graduate schools from 90% to 100%.

Public Health Relevance

The proposed MARC U-STAR grant would increase the pool of under-represented minority (URM) research scientists, this will be achieved by offering enhanced curricula and rigorous undergraduate research experiences to maximize the competitiveness of students in entering and completing Ph.D. programs in biomedical research. The diversity of the students that emerge from the program will provide a more nuanced and sensitive approach to the host of public health challenges that occur among the increasingly diverse population.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
MARC Undergraduate NRSA Institutional Grants (T34)
Project #
5T34GM007663-33
Application #
8668962
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Gaillard, Shawn R
Project Start
1980-06-01
Project End
2017-05-31
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
33
Fiscal Year
2014
Total Cost
$396,965
Indirect Cost
$19,405
Name
Tennessee State University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
108814179
City
Nashville
State
TN
Country
United States
Zip Code
37209
Brown, Shyretha; Whalen, Margaret (2015) Tributyltin alters secretion of interleukin 1 beta from human immune cells. J Appl Toxicol 35:895-908
Amara, Suneetha; Lopez, Karina; Banan, Babak et al. (2015) Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: potential role in liver fibrosis. Mol Immunol 64:26-35
Lawrence, Shanieek; Reid, Jacqueline; Whalen, Margaret (2015) Secretion of interferon gamma from human immune cells is altered by exposure to tributyltin and dibutyltin. Environ Toxicol 30:559-71
Al-Masum, Mohammad; Welch, Rebecca L (2014) Catalyst free, base free microwave irradiated synthesis of aryl nitrites from potassium aryltrifluoroborates and bismuth nitrate. Tetrahedron Lett 55:1726-1728
Cato, Anita; Celada, Lindsay; Kibakaya, Esther Caroline et al. (2014) Brominated flame retardants, tetrabromobisphenol A and hexabromocyclododecane, activate mitogen-activated protein kinases (MAPKs) in human natural killer cells. Cell Biol Toxicol 30:345-60
Platt, Derek; Amara, Suneetha; Mehta, Toral et al. (2014) Violacein inhibits matrix metalloproteinase mediated CXCR4 expression: potential anti-tumor effect in cancer invasion and metastasis. Biochem Biophys Res Commun 455:107-12
Xue, Stephen Y; Hebert, Valeria Y; Hayes, Danicia M et al. (2013) Nucleoside reverse transcriptase inhibitors induce a mitophagy-associated endothelial cytotoxicity that is reversed by coenzyme Q10 cotreatment. Toxicol Sci 134:323-34
Chen, Chau-Kuang; Bruce, Michelle; Tyler, Lauren et al. (2013) Analysis of an environmental exposure health questionnaire in a metropolitan minority population utilizing logistic regression and Support Vector Machines. J Health Care Poor Underserved 24:153-71
Hurd-Brown, Tasia; Udoji, Felicia; Martin, Tamara et al. (2013) Effects of DDT and triclosan on tumor-cell binding capacity and cell-surface protein expression of human natural killer cells. J Appl Toxicol 33:495-502
Al-Masum, Mohammad; Saleh, Nabil; Islam, Tasfia (2013) A novel route to organonitrites by Pd-catalyzed cross-coupling of sodium nitrite and potassium organotrifluoroborates. Tetrahedron Lett 54:1141-1144

Showing the most recent 10 out of 11 publications