The overall aim of this competitive continuation proposal for the SDSU MARC-U*STAR is to increase the number of students from underrepresented groups who attain Ph.D. degrees in the biomedical, behavioral, quantitative, and physical sciences. We will offer a program of graduate school preparation that includes: mentored research experiences by dedicated research mentors, so that MARC scholars acquire excellent research and laboratory skills and contribute to manuscripts leading to presentations and publications;workshops, professional development and an academic curriculum designed to develop critical thinking, quantitative, and oral and written communication skills;and opportunities to present research before professional audiences. We will work with the myriad student development projects organized under the Center for the Advancement of Students in Academia (CASA), in the College of Sciences (COS). CASA has developed into a mature program of student support through working collaboratively with extramurally funded student programs and leveraging internal SDSU and COS support. Collaboration with other student success programs in Division of Undergraduate Studies (DUS) will establish a sustainable Pre-MARC program that will identify and recruit freshmen and sophomores majoring in STEM disciplines and provide them with experiences to enhance their engagement in science while developing their capacity to address disciplinary and interdisciplinary scientific questions. Through Pre-MARC activities, the pool of students eligible and ready to apply to MARC scholars will be increased. By partnering with programs that have similar or synergistic objectives, we expect the SDSU MARC program will continue to further the goal of increasing the numbers of underrepresented scientists who are competitively trained to pursue careers in biomedical or behavioral research. A strong evaluation component that includes comparisons against baseline data will provide evidence-based documentation of student success and we will use such evaluative data and feedback to continue to improve our outcomes. Our training program will result in students with strong, highly competitive applications for doctoral training programs such that 60% our graduating seniors will enter directly into Ph.D. programs in the biomedical, behavioral and/or physical sciences in the first year, with 5% increase each year thereafter, resulting in 80% entering doctoral program by the end of the funding cycle in 2014.

Public Health Relevance

The need to increase underrepresented students trained in bio-medically related STEM disciplines is underscored by the profound disparity in health status among racial and ethnic minorities. The cause of the disparities is complex and no doubt the result of biological, environmental and behavioral factors compounded by economic and educational inequities. Demographic changes anticipated over the next 2-3 decades magnify the importance of addressing health disparities.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
MARC Undergraduate NRSA Institutional Grants (T34)
Project #
Application #
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Gaillard, Shawn R
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Budget End
Support Year
Fiscal Year
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San Diego State University
Schools of Arts and Sciences
San Diego
United States
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Affan, Rifqi O; Huang, Siyuan; Cruz, Stephen M et al. (2018) High-intensity binge drinking is associated with alterations in spontaneous neural oscillations in young adults. Alcohol 70:51-60
Avellaneda Matteo, Diego; Grunseth, Adam J; Gonzalez, Eric R et al. (2017) Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency. J Biol Chem 292:7971-7983
Graves, Lisa V; Moreno, Charles C; Seewald, Michelle et al. (2017) Effects of Age and Gender on Recall and Recognition Discriminability. Arch Clin Neuropsychol 32:972-979
Basa, Ranor C B; Davies, Vince; Li, Xiaoxiao et al. (2016) Decreased Anti-Tumor Cytotoxic Immunity among Microsatellite-Stable Colon Cancers from African Americans. PLoS One 11:e0156660
Mu, Rong; Kim, Brandon J; Paco, Czarinah et al. (2014) Identification of a group B streptococcal fibronectin binding protein, SfbA, that contributes to invasion of brain endothelium and development of meningitis. Infect Immun 82:2276-86
Banerjee, Anirban; Thamphiwatana, Soracha; Carmona, Ellese M et al. (2014) Deficiency of the myeloid differentiation primary response molecule MyD88 leads to an early and rapid development of Helicobacter-induced gastric malignancy. Infect Immun 82:356-63
Cowles, Martis W; Omuro, Kerilyn C; Stanley, Brianna N et al. (2014) COE loss-of-function analysis reveals a genetic program underlying maintenance and regeneration of the nervous system in planarians. PLoS Genet 10:e1004746
Murray, Kate E; Barbour, Lynda; Morlett, Alejandra et al. (2014) Latinos and political advocacy for cancer control in a United States-Mexico border community. Hisp Health Care Int 12:198-206
Melkani, Girish C; Trujillo, Adriana S; Ramos, Raul et al. (2013) Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart. PLoS Genet 9:e1004024
Konstandin, Mathias H; Völkers, Mirko; Collins, Brett et al. (2013) Fibronectin contributes to pathological cardiac hypertrophy but not physiological growth. Basic Res Cardiol 108:375

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