The T35 Program for Health Professional Students at the University of Chicago is aimed at promoting the career development of physician scientists who will view research activity and biomedical investigation as an essential part of their long-term professional goals, particularly in the mission areas of the NIDDK (digestive diseases, diabetes/metabolism, kidney/urological diseases). The program provides students with a wide choice of opportunities for high quality, mentor-based research over a 12 weeks training spanning the spring quarter of the 1st year to the beginning of 2nd year of medical school. The program selects highly qualified trainees by means of a formal application and evaluation process. Students are counseled to identify a research project and select mentor from any of the clinical and basic science departments of the Biological Sciences Division (BSD)). Several mechanisms are used to oversee the program and student progress, including weekly cluster group meetings, a web-based reporting system that sets weekly benchmarks for students, and regular performance review by steering committee members. In addition, the program requires students to submit a final written report and to present their findings to peers and faculty at the closing scientific research forum. In addition to doing hypothesis-driven research, students undergo didactic and case-based training in the responsible conduct of research and instruction in bioinformatics and biostatistics. To assess the immediate and long-term impact of the program, a tracking system has been developed by the Medical Education and Alumni Affairs office. Trainees will be followed up to 15 years after graduation to continually assess the impact of the program in promoting further research activities and career choices in NIDDK mission areas. By early indicators, the program is enormously successful, attracting the best and most highly qualified students. Since 2004, 50% or more of the students have selected research investigations in NIDDK mission areas. We are requesting continued support for the research training of 30 students/year. The program enjoys strong institutional support, evidenced by cost-sharing, provision of space, resources, and training by the BSD, CTSA, and NIDDK-supported DDRCC and DRTC. In addition, the program is a key component of the Scholarship and Discovery program of the revised medical curriculum that includes other federally funded pre and post doctoral training grants and an MSTP training program. The academic base of the University includes other large research centers and programs, a 650-bed teaching hospital, a large and well equipped physical plant for biomedical research, a HHMI, and a research base of over 250 investigators who hold peer-reviewed grant support. In addition, the University has particularly strong research strengths in the areas of Diabetes, Digestive Diseases and Kidney Disease, exemplified by the robust interactions/collaborations and many NIH and extramural institutional and individual research grants in these areas. Thus, the environment is ideal to support the goals of this NIDDK-supported medical student T35 program.

Public Health Relevance

The Short Term Training Program for Health Professional Students at the University of Chicago promotes the career development of physician scientists in the mission areas of the NIDDK by providing medical students with a wide choice of opportunities for high quality, mentor-based research within a highly supportive environment of scholarship and discovery.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NRSA Short -Term Research Training (T35)
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Special Emphasis Panel (ZDK1)
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Castle, Arthur
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University of Chicago
Internal Medicine/Medicine
Schools of Medicine
United States
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Tallman, Jacob E; Packiam, Vignesh T; Wroblewski, Kristen E et al. (2017) Influence of pathologist experience on positive surgical margins following radical prostatectomy. Urol Oncol 35:461.e1-461.e6
Lee, Yee Ming; McKillip, Ryan P; Borden, Brittany A et al. (2017) Assessment of patient perceptions of genomic testing to inform pharmacogenomic implementation. Pharmacogenet Genomics 27:179-189
McKillip, R P; Borden, B A; Galecki, P et al. (2016) Patient Perceptions of Care as Influenced by a Large Institutional Pharmacogenomic Implementation Program. Clin Pharmacol Ther :
Halverson, Colin M E; Wang, Jackie Y; Poulson, Michael et al. (2016) Living Kidney Donors Who Develop Kidney Failure: Excerpts of Their Thoughts. Am J Nephrol 43:389-96
Sathe, Neha A; Nocon, Robert S; Hughes, Brenna et al. (2016) The Costs of Participating in a Diabetes Quality Improvement Collaborative: Variation Among Five Clinics. Jt Comm J Qual Patient Saf 42:18-25
Berthoud, Viviana M; Minogue, Peter J; Lambert, Paul A et al. (2016) The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses. J Biol Chem 291:17569-78
Liu, G Y; Utset, T O; Bernard, J T (2015) Retinal nerve fiber layer and macular thinning in systemic lupus erythematosus: an optical coherence tomography study comparing SLE and neuropsychiatric SLE. Lupus 24:1169-76
Kubic, Jennifer D; Lui, Jason W; Little, Elizabeth C et al. (2015) PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma. J Biol Chem 290:21901-14
Kim, Julius W; Young, Jacob S; Solomaha, Elena et al. (2015) A novel single-chain antibody redirects adenovirus to IL13R?2-expressing brain tumors. Sci Rep 5:18133
Lu, Chen-Yuan Emily; Vinci, Lisa M; Quinn, Michael T et al. (2015) Using feedback to change primary care physician behavior. J Ambul Care Manage 38:118-24

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