The number of US citizens with vision compromising diseases is expected to continue to increase over the next several decades. Programs are needed to provide trainees with the skills to conduct research that helps prevent and treat eye diseases and other vision disorders. Physician scientists bring a unique perspective to vision research and are a critical component of future advances in this area. This program will focus on recruiting and training medical students, preparing them for careers as vision researchers. The program includes both core and individualized curricular components. Core curricular components include a seminar on visual function and disease, an ongoing work-in-progress seminar with both faculty and trainee involvement, and a seminar related to the Responsible Conduct of Research. The individualized curricular components include both class work and direct project experience, including dissemination, mentored by an experienced vision researcher. Both short-term intensive and longitudinal training components are included; students will enter the program as first-year medical students and be involved in the program over all 4 years of medical school. Four new students per year will be recruited for a total of 16 students in the program at any time. There will be ongoing evaluation of the program including both student feedback and outcome assessment. This will include short (e.g. student satisfaction), intermediate (early publication and attitude changes), and long-term (long-term publication rates and success at receiving research grants) outcomes. A Senior Advisory Board will provide oversight for the program and ensure use of the outcome data for ongoing quality improvement of the program.

Public Health Relevance

The number of US citizens with vision compromising diseases is expected to continue to increase over the next several decades. Physician scientists add a unique and critical perspective to research that helps prevent and treat eye diseases and other vision disorders. This program will recruit and train medical students for careers as leaders in vision research.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
NRSA Short -Term Research Training (T35)
Project #
5T35EY021455-05
Application #
8825501
Study Section
Special Emphasis Panel (ZEY1-VSN (01))
Program Officer
Agarwal, Neeraj
Project Start
2011-01-01
Project End
2015-12-31
Budget Start
2015-09-01
Budget End
2015-12-31
Support Year
5
Fiscal Year
2015
Total Cost
$9,763
Indirect Cost
$723
Name
University of Colorado Denver
Department
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Groman-Lupa, Sergio; Adewumi, Joseph; Park, Ko Uoon et al. (2017) The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina. Invest Ophthalmol Vis Sci 58:5421-5433
Hua, Jeremy T; Hildreth, Kerry L; Pelak, Victoria S (2016) Effects of Testosterone Therapy on Cognitive Function in Aging: A Systematic Review. Cogn Behav Neurol 29:122-38
Diego, Jose L; Bidikov, Luke; Pedler, Michelle G et al. (2016) Effect of human milk as a treatment for dry eye syndrome in a mouse model. Mol Vis 22:1095-1102
Snow, Anson; Shieh, Biehuoy; Chang, Kun-Che et al. (2015) Aldose reductase expression as a risk factor for cataract. Chem Biol Interact 234:247-53
Chang, Kun-Che; Snow, Anson; LaBarbera, Daniel V et al. (2015) Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells. Chem Biol Interact 234:254-60
Christopher, Karen L; Pedler, Michelle G; Shieh, Biehuoy et al. (2014) Alpha-crystallin-mediated protection of lens cells against heat and oxidative stress-induced cell death. Biochim Biophys Acta 1843:309-15
Zablocki, Gregory J; Ruzycki, Philip A; Overturf, Michelle A et al. (2011) Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens. Chem Biol Interact 191:351-6