This continuing multifaceted University of Arizona (DA) short-term Medical Student Research Program (MSRP) seeks to introduce, train and nurture inquiring medical students in basic and clinical medical research;and further, to provide the stimulus for subsequent intensive and extensive research experiences. Building on the past 25 years of high level participation, esprit-de-corps, and outstanding trainee productivity (research presentations, publications, awards, and advanced research), full-time opportunities for summer/ vacation laboratory and clinical investigation will be offered under experienced faculty mentors predominantly concentrated in Specialized Centers of Excellence focusing on in vivo, in vitro, in situ, in silico and modeling approaches to the cardiovascular system and its disorders (e.g. heart failure, developmental abnormalities, cardiac arrest/resuscitation, transplantation, artificial hearts, lymphedema-angiodysplasia syndromes);cancer (e.g., prevention, epidemiology, detection, pharmacogenomics, drug development);neurosciences (e.g., cognition, molecular psychiatry, neurotransmitters, drug addiction, neural regeneration), and a variety of other areas spanning the full spectrum of research topics in children, adults and special populations so as to capture the individual interests and talents of medical students. The research experience will be integrated into an innovative Curriculum on Medical Ignorance (CMI), concentrated in a Summer Institute and complemented by a menu of year-round trainee-related activities (seminars and workshops, clinical correlations, advanced extracurricular research through a student-initiated Research Honors Distinction Track, visiting professorships, """"""""thriving"""""""" workshops, and career advising), open to all medical students.
CMI aims to foster attitudes and skills to recognize and deal with the vast shifting world of medical ignorance [""""""""what we know we don't know (current research), don't know we don't know (future discovery), and think we know but don't (error)""""""""] from molecular to clinical medicine. Detailed short-term and long-term formative and summative evaluation of the program and participants, including database registry, individual development plans, and career portfolios, will be continued to document effectiveness and promote networking.

Public Health Relevance

Based on our 25-year track record reflected in the most recent MSRP followup, we anticipate cultivating a large number of scientific physicians who understand and can contribute to the research enterprise and, in increasing numbers, a growing cadre of enlightened physician-scientist leaders to replenish the dwindling supply of translational medical researchers and fulfill the NIH Roadmap goal to expedite the movements of scientific advances from bench to bedside to community.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
NRSA Short -Term Research Training (T35)
Project #
Application #
Study Section
Special Emphasis Panel (ZHL1-CSR-K (O1))
Program Officer
Meadows, Tawanna
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Arizona
Schools of Medicine
United States
Zip Code
Frankl, Joseph; Sakata, Michael P; Choudhary, Gagandeep et al. (2016) A Classification System for the Spread of Polymethyl Methacrylate in Vertebral Bodies Treated with Vertebral Augmentation. Tomography 2:197-202
Moutal, Aubin; Eyde, Nathan; Telemi, Edwin et al. (2016) Efficacy of (S)-Lacosamide in preclinical models of cephalic pain. Pain Rep 1:
Mosier, Jarrod M; Sakles, John C; Stolz, Uwe et al. (2015) Neuromuscular blockade improves first-attempt success for intubation in the intensive care unit. A propensity matched analysis. Ann Am Thorac Soc 12:734-41
Duscher, Dominik; Rennert, Robert C; Januszyk, Michael et al. (2014) Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells. Sci Rep 4:7144
Gruessner, Christine; Gruessner, Angelika; Glaser, Katherine et al. (2014) Flutamide and biomarkers in women at high risk for ovarian cancer: preclinical and clinical evidence. Cancer Prev Res (Phila) 7:896-905
Luber, Adam J; Tsui, Cindy L; Heinecke, Gillian M et al. (2014) Long-term durability and dose escalation patterns in infliximab therapy for psoriasis. J Am Acad Dermatol 70:525-32
Yue, X; Hariri, D J; Caballero, B et al. (2014) Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson's disease. Neuroscience 258:385-400
Mosier, Jarrod; Chiu, Stephen; Patanwala, Asad E et al. (2013) A comparison of the GlideScope video laryngoscope to the C-MAC video laryngoscope for intubation in the emergency department. Ann Emerg Med 61:414-420.e1
Sakles, John C; Chiu, Stephen; Mosier, Jarrod et al. (2013) The importance of first pass success when performing orotracheal intubation in the emergency department. Acad Emerg Med 20:71-8
Melemedjian, Ohannes K; Tillu, Dipti V; Asiedu, Marina N et al. (2013) BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Mol Pain 9:12

Showing the most recent 10 out of 55 publications