This continuing multifaceted University of Arizona (DA) short-term Medical Student Research Program (MSRP) seeks to introduce, train and nurture inquiring medical students in basic and clinical medical research;and further, to provide the stimulus for subsequent intensive and extensive research experiences. Building on the past 25 years of high level participation, esprit-de-corps, and outstanding trainee productivity (research presentations, publications, awards, and advanced research), full-time opportunities for summer/ vacation laboratory and clinical investigation will be offered under experienced faculty mentors predominantly concentrated in Specialized Centers of Excellence focusing on in vivo, in vitro, in situ, in silico and modeling approaches to the cardiovascular system and its disorders (e.g. heart failure, developmental abnormalities, cardiac arrest/resuscitation, transplantation, artificial hearts, lymphedema-angiodysplasia syndromes);cancer (e.g., prevention, epidemiology, detection, pharmacogenomics, drug development);neurosciences (e.g., cognition, molecular psychiatry, neurotransmitters, drug addiction, neural regeneration), and a variety of other areas spanning the full spectrum of research topics in children, adults and special populations so as to capture the individual interests and talents of medical students. The research experience will be integrated into an innovative Curriculum on Medical Ignorance (CMI), concentrated in a Summer Institute and complemented by a menu of year-round trainee-related activities (seminars and workshops, clinical correlations, advanced extracurricular research through a student-initiated Research Honors Distinction Track, visiting professorships, """"""""thriving"""""""" workshops, and career advising), open to all medical students.
CMI aims to foster attitudes and skills to recognize and deal with the vast shifting world of medical ignorance [""""""""what we know we don't know (current research), don't know we don't know (future discovery), and think we know but don't (error)""""""""] from molecular to clinical medicine. Detailed short-term and long-term formative and summative evaluation of the program and participants, including database registry, individual development plans, and career portfolios, will be continued to document effectiveness and promote networking.

Public Health Relevance

Based on our 25-year track record reflected in the most recent MSRP followup, we anticipate cultivating a large number of scientific physicians who understand and can contribute to the research enterprise and, in increasing numbers, a growing cadre of enlightened physician-scientist leaders to replenish the dwindling supply of translational medical researchers and fulfill the NIH Roadmap goal to expedite the movements of scientific advances from bench to bedside to community.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
NRSA Short -Term Research Training (T35)
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Special Emphasis Panel (ZHL1-CSR-K (O1))
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Meadows, Tawanna
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University of Arizona
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United States
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Costello, C M; Ghanavatian, S; Temkit, M et al. (2017) Educational and practice gaps in the management of volar melanocytic lesions. J Eur Acad Dermatol Venereol :
Yun, Seongseok; Johnson, Ariel C; Okolo, Onyemaechi N et al. (2017) Waldenström Macroglobulinemia: Review of Pathogenesis and Management. Clin Lymphoma Myeloma Leuk 17:252-262
Moutal, Aubin; Villa, Lex Salas; Yeon, Seul Ki et al. (2017) CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation. Mol Neurobiol :
Harryman, William L; Gard, Jaime M C; Pond, Kelvin W et al. (2017) Targeting the Cohesive Cluster Phenotype in Chordoma via ?1 Integrin Increases Ionizing Radiation Efficacy. Neoplasia 19:919-927
Moutal, Aubin; Eyde, Nathan; Telemi, Edwin et al. (2016) Efficacy of (S)-Lacosamide in preclinical models of cephalic pain. Pain Rep 1:
Frankl, Joseph; Sakata, Michael P; Choudhary, Gagandeep et al. (2016) A Classification System for the Spread of Polymethyl Methacrylate in Vertebral Bodies Treated with Vertebral Augmentation. Tomography 2:197-202
Mosier, Jarrod M; Sakles, John C; Stolz, Uwe et al. (2015) Neuromuscular blockade improves first-attempt success for intubation in the intensive care unit. A propensity matched analysis. Ann Am Thorac Soc 12:734-41
Gruessner, Christine; Gruessner, Angelika; Glaser, Katherine et al. (2014) Flutamide and biomarkers in women at high risk for ovarian cancer: preclinical and clinical evidence. Cancer Prev Res (Phila) 7:896-905
Luber, Adam J; Tsui, Cindy L; Heinecke, Gillian M et al. (2014) Long-term durability and dose escalation patterns in infliximab therapy for psoriasis. J Am Acad Dermatol 70:525-32
Duscher, Dominik; Rennert, Robert C; Januszyk, Michael et al. (2014) Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells. Sci Rep 4:7144

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