There is a critical shortage of veterinarians with training in experimental design and research technologies, which is evidenced by the great demand for competent veterinary researchers sought by veterinary colleges, medical schools, and federal agencies. In particular, veterinary scientists are necessary to address two critical areas of need for biomedical research: translational medicine and emerging infectious diseases. At the Mississippi State University College of Veterinary Medicine, we are particularly well suited to address these areas of need. Our long-term goal is to contribute to the national capacity of veterinarians in biomedical research by engaging and educating veterinary students in biomedical research. The immediate goal of this application is to involve veterinary students in short-term research training opportunities supported by the Ruth L. Kirschstein NRSA Short-Term Institutional Research Training Grants (T35) program. Specifically, MSU-CVM proposes to administer a Summer Research Experience Program to recruit and train veterinary students in biomedical research. Another important goal of our program is to increase diversity in the veterinary research workforce. To accomplish this, we will build on an already existing collaboration with Tuskegee University School of Veterinary Medicine to recruit minority students. Our program will provide summer research experiences for twelve veterinary students each year that have completed their freshman, sophomore, or junior year in an AVMA- accredited veterinary curriculum. The proposed training will consist of a continuous twelve week block of time in summer. The program will have three major components: 1) research conducted under the mentorship of an active faculty researcher, 2) educational activities in research, career development, and leadership, and 3) training and experience in preparation of scientific presentations. MSU-CVM has unique research programs to give trainees experience in toxicology, biomedical research (including animal models for human disease), genomics/functional genomics, computational biology, infectious disease, or food safety.
Currently, there is need for translating basic medical discoveries into useful diagnostics and treatments using animal models. There is also concern about biowarfare, particularly with infectious agents that are spread from animals to humans. In the U.S., there is a shortage of veterinary researchers to address these issues. This proposed short-term research program for veterinary students will prepare them for research careers.
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|Lee, J K; Moraru, G M; Stokes, J V et al. (2017) Rickettsia parkeri and ""Candidatus Rickettsia andeanae"" in Questing Amblyomma maculatum (Acari: Ixodidae) From Mississippi. J Med Entomol 54:476-480|
|Fellman, C L; Archer, T M; Stokes, J V et al. (2016) Effects of oral cyclosporine on canine T-cell expression of IL-2 and IFN-gamma across a 12-h dosing interval. J Vet Pharmacol Ther 39:237-44|
|Ross, Matthew K; Pluta, Kim; Bittles, Victoria et al. (2016) Interaction of the serine hydrolase KIAA1363 with organophosphorus agents: Evaluation of potency and kinetics. Arch Biochem Biophys 590:72-81|
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|Coyne, C P; Narayanan, Lakshmi (2015) Fludarabine- (C2-methylhydroxyphosphoramide)- [anti-IGF-1R]: Synthesis and Selectively ""Targeted""Anti-Neoplastic Cytotoxicity against Pulmonary Adenocarcinoma (A549). J Pharm Drug Deliv Res 4:|
|Szafran, Brittany; Borazjani, Abdolsamad; Lee, Jung Hwa et al. (2015) Lipopolysaccharide suppresses carboxylesterase 2g activity and 2-arachidonoylglycerol hydrolysis: A possible mechanism to regulate inflammation. Prostaglandins Other Lipid Mediat 121:199-206|
|Coyne, C P; Jones, Toni; Bear, Ryan (2015) Simultaneous Dual Selective Targeted Delivery of Two Covalent Gemcitabine Immunochemotherapeutics and Complementary Anti-Neoplastic Potency of [Se]-Methylselenocysteine. J Cancer Ther 6:62-89|
|Weaver, Kriston F; Stokes, John V; Gunnoe, Sagen A et al. (2014) EFFECT OF LIPOSOMAL CLODRONATE-DEPENDENT DEPLETION OF PROFESSIONAL ANTIGEN PRESENTING CELLS ON NUMBERS AND PHENOTYPE OF CANINE CD4+CD25+FOXP3+ REGULATORY T CELLS. J Vet Med Res 1:|
|Ammari, Mais G; Harris, Autumn N; Stokes, John V et al. (2014) NEGATIVE REGULATORY EFFECTS OF PHOSPHATIDYLINOSITOL3-KINASE PATHWAY ON PHAGOCYTOSIS AND MACROPINOCYTOSIS IN BOVINE MONOCYTES. J Vet Med Res 1:|
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