The National Research Council has documented a dire national need for veterinary specialists trained in biomedical research. Furthermore, veterinary researchers play a key role in multidisciplinary and interdisciplinary research activitis since they naturally bridge basic and clinical research. To address this training need, faculty in the North Carolina State University College of Veterinary Medicine (CVM) established the Interdisciplinary Biomedical Research Training Program (IBRTP) for veterinary students in 2009. The objective of this training program is to provide interdisciplinary biomedical research experience specifically targeted to veterinary students with a strong interest in a research career. The training program also serves as a bridge to foster new interdisciplinary research collaborations amongst faculty members. Trainees complete a 3-month research experience in the laboratories of faculty members drawn from nine different disciplines. Trainees are mentored by two faculty members from different disciplines to create and execute an interdisciplinary project. The 29 faculty members participating in this program are well funded and have a strong training track record. The nine disciplines selected are areas of strength at NC State;Clinical Sciences, Cellular and Molecular Biology, Genetics and Genomics, Engineering, Food Safety, Statistics, Pharmacology, Regenerative Medicine, and Toxicology. Research projects emphasize the melding of two disciplines to create a novel approach to a biomedical research problem. Projects combining clinical and basic science disciplines are given priority. Trainees will be veterinary students in their first or second year who are building on prior research experience. The training program started in 2009 with funds committed by NC State University CVM. Four trainee slots funded by the NIH were added in 2010. The number of NIH supported trainee slots grew to 7 in 2012. To date, a total of 22 NIH funded trainees have completed the program. We propose in this renewal application that the number of NIH funded training slots be increased to 10 per year. Program requirements include: (1) a weekly seminar series on topics related to research ethics and scientific and professional development;(2) a weekly journal club discussing interdisciplinary research papers;(3) participation in the NIH-Merial National Veterinary Scholars Symposium and the annual CVM research symposium. These requirements are in addition to those associated with a student's research training experience.

Public Health Relevance

This Interdisciplinary Biomedical Research training program (IBRTP) addresses two critical national needs in biomedical research. First is the growing need for Veterinarians with training in biomedical research. Second is that more emphasis needs to be placed on translation of basic research advances to the clinical setting and this often requires an interdisciplinary approach.

Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
NRSA Short -Term Research Training (T35)
Project #
2T35OD011070-06
Application #
8742217
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Moro, Manuel H
Project Start
2009-06-01
Project End
2019-08-31
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
6
Fiscal Year
2014
Total Cost
Indirect Cost
Name
North Carolina State University Raleigh
Department
Other Clinical Sciences
Type
Schools of Veterinary Medicine
DUNS #
City
Raleigh
State
NC
Country
United States
Zip Code
27695
Blau, S R; Davis, L M; Gorney, A M et al. (2017) Quantifying center of pressure variability in chondrodystrophoid dogs. Vet J 226:26-31
Pohl, C S; Medland, J E; Mackey, E et al. (2017) Early weaning stress induces chronic functional diarrhea, intestinal barrier defects, and increased mast cell activity in a porcine model of early life adversity. Neurogastroenterol Motil 29:
Fenn, J; Laber, E; Williams, K et al. (2017) Associations Between Anesthetic Variables and Functional Outcome in Dogs With Thoracolumbar Intervertebral Disk Extrusion Undergoing Decompressive Hemilaminectomy. J Vet Intern Med 31:814-824
Mercadante, Courtney J; Herrera, Carolina; Pettiglio, Michael A et al. (2016) The effect of high dose oral manganese exposure on copper, iron and zinc levels in rats. Biometals 29:417-22
Gorney, A M; Blau, S R; Dohse, C S et al. (2016) Mechanical and Thermal Sensory Testing in Normal Chondrodystrophoid Dogs and Dogs with Spinal Cord Injury caused by Thoracolumbar Intervertebral Disc Herniations. J Vet Intern Med 30:627-35
Swartley, Olivia M; Foley, Julie F; Livingston 3rd, David P et al. (2016) Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5-18.5 and Early Postnatal Development. Toxicol Pathol 44:705-25
Newman, Donna R; Sills, W Shane; Hanrahan, Katherine et al. (2016) Expression of WNT5A in Idiopathic Pulmonary Fibrosis and Its Control by TGF-? and WNT7B in Human Lung Fibroblasts. J Histochem Cytochem 64:99-111
Mackey, Emily; Ayyadurai, Saravanan; Pohl, Calvin S et al. (2016) Sexual dimorphism in the mast cell transcriptome and the pathophysiological responses to immunological and psychological stress. Biol Sex Differ 7:60
Womble, Mandy; Pickett, Melissa; Nascone-Yoder, Nanette (2016) Frogs as integrative models for understanding digestive organ development and evolution. Semin Cell Dev Biol 51:92-105
Shapiro, S G; Knapp, D W; Breen, Matthew (2015) A cultured approach to canine urothelial carcinoma: molecular characterization of five cell lines. Canine Genet Epidemiol 2:15

Showing the most recent 10 out of 27 publications