The goal of this project is to increase minority participation in biomedical research through an educational and research program that is formulated to assist minority serving institutions establishing bioinformatics programs ranging in size from a single course to a degree program. We will assist five primary partners that have established a sequence based bioinformatics course in developing a more extensive bioinformatics program consisting of multiple courses, degrees/certificates, publications and grant support. In addition, we will continue to assist in establishing initial courses with a rotating series of informal partners. We will also enhance our support with an online, educational computational center and learning environment. This center will facilitate educational initiatives with a stand-alone streaming set of multimedia modules covering critical bioinformatics concepts ranging from basic biology to advanced bioinformatics topics to applying bioinformatics software in optimal ways. In addition, the center will serve as a self paced interdisciplinary bioinformatics resource for students and faculty at minority serving institutions enabling bioinformatics resources to be accessed through an environment that provides educational support. Specifically we will achieve this goal through a four component program that includes: 1) Improving the curriculum at minority serving institutions by adding bioinformatics components into multiple courses and in multiple departments, and integrating bioinformatics into research projects. 2) A summer institute which trains faculty from minority serving institutions in bioinformatics teaching and research techniques. 3) An Online Educational Center and learning environment featuring online interdisciplinary teaching resources supplemented with multimedia modules, bioinformatics software and problem sets. 4) An eight week research internship focused on publishable research results. This four component program assists minority serving institutions by embedding aspects of bioinformatics into a broad swath of scientific disciplines in both coursework and research activities.

Public Health Relevance

This project assists minority scientists in making their research more effective and efficient by training them to make use of modern bioinformatics techniques to exploit the large amount of sequence, genomics, and protein structural data being generated in biomedical research.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
MARC Ancillary Training Activities (Grant) (NIGMS) (T36)
Project #
Application #
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Gaillard, Shawn R
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Carnegie-Mellon University
Biostatistics & Other Math Sci
Schools of Arts and Sciences
United States
Zip Code
Martinez, Teresa; Martinez, Idali; Vazquez, Guillermo J et al. (2016) Genetic environment of the KPC gene in Acinetobacter baumannii ST2 clone from Puerto Rico and genomic insights into its drug resistance. J Med Microbiol 65:784-92
Padín-Irizarry, Vivian; Colón-Lorenzo, Emilee E; Vega-Rodríguez, Joel et al. (2016) Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage. Free Radic Biol Med 95:43-54
Rodriguez, Yacidzohara; Gonzalez-Mendez, Ricardo R; Cadilla, Carmen L (2016) Evolution of the Twist Subfamily Vertebrate Proteins: Discovery of a Signature Motif and Origin of the Twist1 Glycine-Rich Motifs in the Amino-Terminus Disordered Domain. PLoS One 11:e0161029
Martínez, Teresa; Ropelewski, Alexander J; González-Mendez, Ricardo et al. (2016) Draft Genome Sequence of a Multidrug-Resistant Klebsiella pneumoniae Carbapenemase-Producing Acinetobacter baumannii Sequence Type 2 Isolate from Puerto Rico. Genome Announc 4:
Camacho-Cáceres, Katia I; Acevedo-Díaz, Juan C; Pérez-Marty, Lynn M et al. (2015) Multiple criteria optimization joint analyses of microarray experiments in lung cancer: from existing microarray data to new knowledge. Cancer Med 4:1884-900
Lorenzo, Enery; Camacho-Caceres, Katia; Ropelewski, Alexander J et al. (2015) An Optimization-Driven Analysis Pipeline to Uncover Biomarkers and Signaling Paths: Cervix Cancer. Microarrays (Basel) 4:287-310
Isokpehi, Raphael D; Wollenberg Valero, Katharina C; Graham, Barbara E et al. (2015) Secondary Data Analytics of Aquaporin Expression Levels in Glioblastoma Stem-Like Cells. Cancer Inform 14:95-103
Darris, Carl E; Tyus, James E; Kelley, Gary et al. (2015) Molecular tools to support metabolic and immune function research in the Guinea Fowl (Numida meleagris). BMC Genomics 16:358
Martínez, Teresa; Ropelewski, Alexander J; González-Mendez, Ricardo et al. (2015) Draft Genome Sequence of Klebsiella pneumoniae Carbapenemase-Producing Acinetobacter baumannii Strain M3AC9-7, Isolated from Puerto Rico. Genome Announc 3:
Isokpehi, Raphael D; Udensi, Udensi K; Simmons, Shaneka S et al. (2014) Evaluative profiling of arsenic sensing and regulatory systems in the human microbiome project genomes. Microbiol Insights 7:25-34

Showing the most recent 10 out of 20 publications