The University of Texas Health Science Center at Houston (UTHSC-H), The University of Texas M.D. Anderson Cancer Center (UT MDACC), and the Memorial Hermann Hospital System wish to renew their Clinical and Translational Science Award (CTSA), which established the Center for Clinical and Translational Sciences (CCTS) in 2006. In the first cycle, the institutions created our CCTS, provided services to 835 investigators in 104 fields, trained KL2 scholars and TL1 trainees, and worked with the greater Houston and Brownsville communities to disseminate health care information and study the unique health issues in Brownsville's Hispanic border population. To further collaborative research in Texas, our CCTS founded the Texas CTSA Consortium and the Lowering the Barriers Program, which has established IRB reciprocity in the University of Texas System. Our CCTS's mission reads: The Center for Clinical and Translational Sciences provides research infrastructure, training and knowledge transfer to expedite the process of translating discovery to practice. We faciliate research and its dissemination for our investigators, our trainees and students, our patients, our local and state population, our Texas CTSA consortium collaborators, and the national CTSA consortium. To this end, we will focus on a thematic structure in the next cycle. Our themes are: 1) Advancing Translational Sciences by Advancing Personalized Therapy (T1 translation) by determing pathophysiology and developing targeted therapeutics and Advancing Community Engagement and dissemination and implementation research (T3/T4 translation); 2) Advancing Clinical Sciences by accelerating and improving new modalities for the design and conduct of clinical research and by accelerating and improving outcomes of research (T2 translation); and 3) Advancing the Clinical and Translational Science Research Workforce (Post-graduate training. Graduate training and research staff training).

Public Health Relevance

The goal of the Center for Clinical and Translational Sciences (CCTS), funded by a Clinical and Translational Science Award, is to move scientific and medical discoveries as fas as possible from the laboratory to the clinic and community, where they can improve the health of the American people. The CCTS trains researchers, provides research services, and works with its communities to learn their helath concerns and spread health care information.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Training Award (TL1)
Project #
4TL1TR000369-10
Application #
9114181
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Merchant, Carol
Project Start
2006-09-30
Project End
2017-05-31
Budget Start
2016-06-01
Budget End
2017-05-31
Support Year
10
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77225
Fahrenholtz, Samuel John; Madankan, Reza; Danish, Shabbar et al. (2018) Theoretical model for laser ablation outcome predictions in brain: calibration and validation on clinical MR thermometry images. Int J Hyperthermia 34:101-111
Qiao, Yang; Gumin, Joy; MacLellan, Christopher J et al. (2018) Magnetic resonance and photoacoustic imaging of brain tumor mediated by mesenchymal stem cell labeled with multifunctional nanoparticle introduced via carotid artery injection. Nanotechnology 29:165101
Briggs, Neima; Wei, Junfei; Versteeg, Leroy et al. (2018) Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm. PLoS Pathog 14:e1007273
Herbrich, Shelley M; Kannan, Sankaranarayanan; Nolo, Riitta M et al. (2018) Characterization of TRKA signaling in acute myeloid leukemia. Oncotarget 9:30092-30105
MacLellan, Christopher J; Fuentes, David; Prabhu, Sujit et al. (2018) A methodology for thermal dose model parameter development using perioperative MRI. Int J Hyperthermia 34:687-696
Callegari, Keri; Maegawa, Shinji; Bravo-Alegria, Javiera et al. (2018) Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration. Cell Commun Signal 16:60
Howe, Matthew D; Atadja, Louise A; Furr, J Weldon et al. (2018) Fibronectin induces the perivascular deposition of cerebrospinal fluid-derived amyloid-? in aging and after stroke. Neurobiol Aging 72:1-13
Madankan, R; Stefan, W; Fahrenholtz, S J et al. (2017) Accelerated magnetic resonance thermometry in the presence of uncertainties. Phys Med Biol 62:214-245
Gao, Ruli; Kim, Charissa; Sei, Emi et al. (2017) Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer. Nat Commun 8:228
Ager, Casey R; Reilley, Matthew J; Nicholas, Courtney et al. (2017) Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity. Cancer Immunol Res 5:676-684

Showing the most recent 10 out of 38 publications