To address the CTSA vision to have a sustained and transformative influence on the quality and value of clinical &translational research, leadership from three academic institutions - Emory University, Morehouse School of Medicine, and Georgia Institute of Technology, along with other collaborative organizations formed in 2007, the Atlanta Clinical and Translational Science Institute (ACTSI). The ACTSI has integrated discovery, education, training and community engagement programs and engendered an unprecedented level of transformation in clinical and translational research in our community. The ACTSI has developed an Atlanta """"""""home"""""""" for clinical and translational research through support of: 673 investigators, 520 projects, 93 pilot projects in 96 research areas, over 193 federal (PHS) grants, 134 current or graduated MSCR, KL, or TL scholars, and over 75 additional active trainees. ACTSI support has also contributed to 661 scientific publications, tripled inter-institutional collaborations, and led to important scientific breakthroughs in clinical and translational science. Guided by the mission, """"""""[tjhrough ethical community engagement, focused education and training, and innovative support of discovery, the collaborative partners ofthe ACTSI rapidly and efficiently translate scientific discoveries to impact all populations ofthe Atlanta community,"""""""" in the next five years, eleven key function programs will be charged with implementing three expanded specific aims.
Aim 1 : Promote discovery through inter-disciplinary collaboration, the development of novel and emerging technologies, drugs, devices, diagnostics and biologies, and the efficient translation of these discoveries to benefit human health.
Aim 2 : Expand and improve outstanding programs to educate and train a growing cadre of ethnically diverse, clinician scientists, and increase the capacity and infrastructure to foster multidisciplinary translational research teams.
Aim 3 : Actively engage the community in research that will engender the public trust in scientific discovery and the translation of new knowledge that ultimately enhances the health ofthe communities we serve.

Public Health Relevance

Created in response to the NIH CTSA program, the Atlanta CTSI serves as a catalyst and incubator for clinical and translational research across Georgia and with regional and national impact. The goals are to create and accelerate clinical and translational science discovery, build interdisciplinary research capacity, engage communities in health sciences activities, develop new research tools and information technologies, and build the careers of clinical/translational scientists ofthe future.

National Institute of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
Linked Training Award (TL1)
Project #
Application #
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Rosenblum, Daniel
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Emory University
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Kuceyeski, A; Monohan, E; Morris, E et al. (2018) Baseline biomarkers of connectome disruption and atrophy predict future processing speed in early multiple sclerosis. Neuroimage Clin 19:417-424
Halani, Sameer H; Yousefi, Safoora; Vega, Jose Velazquez et al. (2018) Multi-faceted computational assessment of risk and progression in oligodendroglioma implicates NOTCH and PI3K pathways. NPJ Precis Oncol 2:24
Shandley, Lisa M; Fothergill, Amy; Spencer, Jessica B et al. (2018) Impact of cancer treatment on risk of infertility and diminished ovarian reserve in women with polycystic ovary syndrome. Fertil Steril 109:516-525.e1
Bowen, Meredith T; Rebello, Leticia C; Bouslama, Mehdi et al. (2018) Clinical and Imaging Outcomes of Endovascular Therapy in Patients with Acute Large Vessel Occlusion Stroke and Mild Clinical Symptoms. Interv Neurol 7:91-98
Adelman, Max W; McFarland, Deborah A; Tsegaye, Mulugeta et al. (2018) Cost-effectiveness of WHO-Recommended Algorithms for TB Case Finding at Ethiopian HIV Clinics. Open Forum Infect Dis 5:ofx269
Yao, Y; Nguyen, T D; Pandya, S et al. (2018) Combining Quantitative Susceptibility Mapping with Automatic Zero Reference (QSM0) and Myelin Water Fraction Imaging to Quantify Iron-Related Myelin Damage in Chronic Active MS Lesions. AJNR Am J Neuroradiol 39:303-310
Correnti, Christina M; Klein, David J; Elliott, Marc N et al. (2018) Racial disparities in fifth-grade sun protection: Evidence from the Healthy Passages study. Pediatr Dermatol 35:588-596
McKay, J Lucas; Lang, Kimberly C; Ting, Lena H et al. (2018) Impaired set shifting is associated with previous falls in individuals with and without Parkinson's disease. Gait Posture 62:220-226
Yousefi, Safoora; Amrollahi, Fatemeh; Amgad, Mohamed et al. (2017) Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models. Sci Rep 7:11707
Gross, Teresa S; Harris, Frank; Brown, Lou Ann S et al. (2017) Ethyl linolenate is elevated in meconium of very-low-birth-weight neonates exposed to alcohol in utero. Pediatr Res 81:461-467

Showing the most recent 10 out of 120 publications