Program Director/Principal Investigator (Last, First. Middle): Selker, Harry P. PROJECT SUMMARY (See Instnjctions): Applying for our second CTSA, Tufts Clinical and Translational Science Institute (CTSl) remains avidly committed to involving the full spectrum of clinical arid translational research (CTR) to meet the promise of biomedical science, not only bench to bedside ( T l """""""" ) translation, crucial to having health impact, translation into effective clinical practice (""""""""T2""""""""), care delivery and public health (""""""""T3""""""""), and health policy ('T4""""""""). In 2008 we started Tufts CTSl building on prior CTR resources, services, and educational programs, we purposely selected partners that would leverage and complement each other's special assets. Our 38 strategically- chosen partners include 12 Tufts University schools/research centers, ten Tufts hospitals, three academic Institutions (Brandeis University, Northeastern University, RAND Corporation), eight community-based organizations, and five industry partners, an outstanding and synergistic resources, opportunities, and education across the T1-T4 spectnjm. Described in our application's four sections are four alms that build on this platform:
AIM 1 : Strengthen Tufts CTSl overall by: 1) organizing and leading its partners in their commitment to this shared home for CTR;2) expanding efficient access for all partners to a full spectrum of high-quality resources in a way that promotes collaborative CTR across disciplines and institutions;3) advancing the field of CTR through local and national leadership and development of novel methods;4) providing innovative and targeted education and training across the T1-4 spectmm. (Section I) AIM 2: Operationalize and implement the CTR home and its infra- stnjcture, services and programs, including its central office personnel, administrative and financial management systems, committees, and other necessary structures. (Section II) AIM 3: Sustain and grow innovative resources, services, and policies that support and promote collaborative, cross-disciplinary, full-spectrum translational research. (Section III) AIM 4:Develop and broaden the CTR workforce through education and training across the T1-T4 spectrum, with a specific focus on addressing translational gaps between bench to bedside and from bedside to widespread impact on health. (Section IV)

Public Health Relevance

(See Instructions): Tufts Clinical and Translational Science Institute uses the entire spectrum of clinical and translational research (CTR) to help meet the promise and the public's needs of biomedical science.This includes bench to bedside (?T1"""""""") translation and crucially for having health impact, translation into effective cllnicalpractlce (""""""""T2""""""""), care delivery and public health (""""""""TS""""""""), and health policy ('74"""""""").

National Institute of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
Linked Training Award (TL1)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-PTM-C (S2))
Program Officer
Wilde, David B
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Tufts University
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Li, David G; Xia, Fan Di; Rana, Jasmine et al. (2018) Factors Influencing Patient Decisions Regarding Treatments for Skin Growths: A Cross-Sectional Study. Dermatol Res Pract 2018:3941347
Mirhashemi, Marzieh Ezzaty; Noubary, Farzad; Chapman-Bonofiglio, Susan et al. (2018) Transcriptome analysis of pig intestinal cell monolayers infected with Cryptosporidium parvum asexual stages. Parasit Vectors 11:176
Li, David G; Cohen, Jeffrey M; Mikailov, Anar et al. (2018) Clinical Diagnostic Accuracy of Onychomycosis: A Multispecialty Comparison Study. Dermatol Res Pract 2018:2630176
Li, David G; LeCompte, Gabrielle; Golod, Lev et al. (2018) Dermal carotenoid measurement is inversely related to anxiety in patients with breast cancer. J Investig Med 66:329-333
Li, David G; Wong, Gordon X; Martin, David T et al. (2017) Attitudes on cost-effectiveness and equity: a cross-sectional study examining the viewpoints of medical professionals. BMJ Open 7:e017251
Otero, Tiffany M N; Barber, Samuel R; Yeh, D Dante et al. (2017) Necrotizing Soft Tissue Infection or Sweet Syndrome: Surgery Versus No Surgery?: A Case Report. A A Case Rep 8:182-185
Babyak, J M; Weiner, D E; Noubary, F et al. (2017) Prevalence of Elevated Serum Creatinine Concentration in Dogs Presenting to a Veterinary Academic Medical Center (2010-2014). J Vet Intern Med 31:1757-1764
Al-Naamani, Nadine; Chirinos, Julio A; Zamani, Payman et al. (2016) Association of Systemic Arterial Properties With Right Ventricular Morphology: The Multi-Ethnic Study of Atherosclerosis (MESA)-Right Ventricle Study. J Am Heart Assoc 5:
Al-Naamani, Nadine; Sagliani, Kristen D; Dolnikowski, Gregory G et al. (2016) Plasma 12- and 15-hydroxyeicosanoids are predictors of survival in pulmonary arterial hypertension. Pulm Circ 6:224-33
Al-Naamani, Nadine; Espitia H, Gaudalupe; Velazquez-Moreno, Hugo et al. (2016) Chronic Thromboembolic Pulmonary Hypertension: Experience from a Single Center in Mexico. Lung 194:315-23

Showing the most recent 10 out of 18 publications