This is an application for a Clinical and Translational Science Award (CTSA) at the Albert Einstein College of Medicine partnered with Montefiore Medical Center. The Einstein-Montefiore Institute for Clinical and Trans- lational Research (ICTR) serves as the home of our CTSA program created in 2007 as the formal research partnership between the two institutions. The ICTR has status as an academic entity with committed space and resources, to advance clinical and translational research (CTR), with authority to sponsor a PhD in clinical investigation and other training and career development programs. The ICTR has transformed CTR within our institutions, and contributed to significant changes beyond our walls. The goals for the new CTSA are;1) To provide integrated resources and services to support and expedite planning, implementation, and completion of CTR across the entire range of research;2) To enhance quality, safety, and efficiency of CTR for all diseases and conditions in our environment;3) To develop new innovations that advance clinical and translational sciences;4) To facilitate the training and career development of a robust translational research workforce. To accomplish these goals, we propose an integrative approach with cross-cutting support for T1-T4 translational sciences, interoperable biomedical informatics, therapeutics development, child health research, and patient- and population-centered outcomes research. We also propose to build on research core services that have evolved and expanded including: 1) Clinical Trials and Regulatory Support Office (CTRSO);2) Clinical Investigation Services Cores (CISC);3) Biostatistics, Epidemiology &Research Design (BERD);4) Biomarker and Analytic Research Core (BARC);5) Biospecimen Repository (BioR); 6) Community Engagement Consultation Core (CECC);7) Research Informatics Core (RIC);and 8) Project Acceleration Resource (PAR). Our Research Training, Education and Career Development program will create an educational environment with a learner-centered approach;focus on the core competencies developed by the CTSA;provide a menu of options to serve learners at various stages of development across the spectrum of clinical and translational research;and to implement novel mentoring approaches.
This CTSA application proposes an Institutional Clinical and Translational Science Award (U54) program that conforms to the mission of the National Center for Advancing Translational Sciences, as expressed in RFA- TR-12-006.
|Kessler, Anne; Dankwa, Selasi; Bernabeu, Maria et al. (2017) Linking EPCR-Binding PfEMP1 to Brain Swelling in Pediatric Cerebral Malaria. Cell Host Microbe 22:601-614.e5|
|Cha, Jiook; Zea-Hernandez, Johanna A; Sin, Sanghun et al. (2017) The Effects of Obstructive Sleep Apnea Syndrome on the Dentate Gyrus and Learning and Memory in Children. J Neurosci 37:4280-4288|
|Rastogi, Deepa; Nico, John; Johnston, Andrew D et al. (2017) CDC42-related genes are upregulated in helper T cells from obese asthmatic children. J Allergy Clin Immunol :|
|Veenstra, Mike; Williams, Dionna W; Calderon, Tina M et al. (2017) Frontline Science: CXCR7 mediates CD14+CD16+ monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS. J Leukoc Biol 102:1173-1185|
|Xu, Hannah F; White, Robert S; Sastow, Dahniel L et al. (2017) Medicaid insurance as primary payer predicts increased mortality after total hip replacement in the state inpatient databases of California, Florida and New York. J Clin Anesth 43:24-32|
|Yeh, M-C; Heo, M; Suchday, S et al. (2016) Translation of the Diabetes Prevention Program for diabetes risk reduction in Chinese immigrants in New York City. Diabet Med 33:547-51|
|Aneke-Nash, Chino S; Dominguez-Islas, Clara; B?žková, Petra et al. (2016) Agreement between circulating IGF-I, IGFBP-1 and IGFBP-3 levels measured by current assays versus unavailable assays previously used in epidemiological studies. Growth Horm IGF Res 26:11-6|
|Andreae, Michael H; Rhodes, Evelyn; Bourgoise, Tyler et al. (2016) An Ethical Exploration of Barriers to Research on Controlled Drugs. Am J Bioeth 16:36-47|
|Andreae, Michael H; White, Robert S; Chen, Kelly Yan et al. (2016) The Effect of Initiatives to Overcome Language Barriers and Improve Attendance: A Cross-Sectional Analysis of Adherence in an Inner City Chronic Pain Clinic. Pain Med :|
|Chen, Tingting; Blanc, Caroline; Eder, Anke Z et al. (2016) Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction. J Infect Dis 214:300-10|
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