Contact PD/PI: Barohn, Richard Joel NRSA-Training-001 (001) TL1 TRAINING CORE: ABSTRACT To address the clinical and translational workforce needs in our region, Frontiers needs to provide high quality training in clinical and translational research across the full spectrum of the workforce. In this application, we propose a TL1 program that builds upon our previous successes and addresses current unmet needs. The overall program goals are to: 1) Assemble interdisciplinary teams of outstanding mentors who will guide trainees in team science-based translational research and career development, 2) Recruit a highly promising and diverse pool of predoctoral and post-doctoral trainees to take full advantage of Frontiers' TL1 training program and team mentorship, 3) Offer a tailored and rigorous program of clinical and translational research training that provides opportunities for trainees to acquire the skills and experience needed to pursue a research-related career, and 4) Implement a comprehensive evaluation of TL1 trainees, their mentors, and the training program using metrics that encourage coordinated evaluation across CTSA hubs. We propose two training tracks within this TL1 program: 1) a 1-year predoctoral training track for clinical doctoral students (4 positions); 2) a 2-year post-doctoral track for clinician scientists (6 positions). The predoctoral track is designed to help clinical doctoral students start on the clinical translational research (CTR) pathway early in their training while the postdoctoral track is designed to help clinicians procure productive faculty research positions in which they will be able to compete for more advanced training grants or pursue their own independent funding. We have identified a strong pool of candidates for both tracks and will bring these trainees together into a rich, interdisciplinary, supportive learning environment. Our innovative and competency-driven training program will be enhanced by interdisciplinary research experiences within research clusters that are already practicing the principles of team science. Each TL1 trainee's experience will be driven by an Individual Development Plan (IDP), which will delineate specific, achievable scientific and career goals. Each objective is linked to specific research, education, and training activities. Training opportunities include formal coursework, workshops, research experiences, opportunities to interact with experts at other institutions, and other activities designed to deliver what scholars need to know, when they need it, in a manner that is convenient and readily accessible. Project Summary/Abstract Page 1467 Contact PD/PI: Barohn, Richard Joel NRSA-Training-001 (001) TL1 TRAINING CORE REFERENCES 1. Pfund C, House S, Asquith P, et al. Training mentors of clinical and translational research scholars: a randomized controlled trial. Acad Med. 2014;89(5):774-782. PMCID: PMC4121731 2. Ghandi M, Fernandez A, Stoff D, et al. Development and implementation of a workshop to enhance the effectiveness of mentors working with diverse mentees in HIV research. AIDS Res Hum Retro. 2014;30(8):730-737. PMCID:PMC4118696 3. Fleming M, House S, Hanson V, et al. The Mentoring Competency Assessment: validation of a new instrument to evaluate skills of research mentors. Acad Med. 2013;88(7):1002-1008. PMCID:PMC3727250 4. CTSI. Optimizing the Practice of

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An Online Curriculum for the Professional Development of Research Mentors. 2015.; www.ctsi.umn.edu/education-and-training/mentoring/mentor-training. 5. Groups CW. CTSA Core Competencies. Clinical and Translational Science Awards. 2011; https://ctsacentral.org/consortium/best-practices/335-2/. 6. Mentoring Development Course. 2015; https://accelerate.ucsf.edu/traiing/mdp-seminar1-meeting. 7. NCI. Team Science Toolkit. Cross-Disciplinary Collaborative Activities Scale. 2015; www.teamsciencetoolkit.cancer.gov/public/TSResourceMeasure.aspx?tid=2&rid=383. 8. Clinical and Translational Science Institute. Optimizing the Practice of

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An Online Curriculum for the Professional Development of Research Mentors. Mentor Training 2015; www.ctsi.umn.edu/education-and-training/mentoring/mentor-training. 9. Mankins M. Harvard Business Review. 2004; https://hbr.org/2004/09/stop-wasting-valuable-time/ar/1. 10. Schwartz T, McCarthy C. Manage your energy, not your time. 2007; https://hbr.org/2007/10/manage- your-energy-not-your-time. 11. Miyaoka A, Spiegelman M, Rau K, Frechtling J. Findings from the CTSA National Evaluation Education and Traiing Study. Rockville, MD.2011. 12. National Research Mentoring Network. 2015.; http://nrmnet.net/. 13. Institute of Medicine. The CTSA Program at NIH: Opportunities for Advancing Clinical and Translational Research. Washington, DC.2013. 14. Mullikin E, Bakken L, Betz N. Assessing research self-efficacy in physician-scientists: The Clinical research appraisal inventory. J Career Assess. 2007;15(3):367-387. Published prior to April 2008. 15. Lipira L, Jeffe D, Krauss M, et al. Evaluation of Clinical Research Training Programs Using Clinical Research Appraisal Inventory. Clin Transl Sci. 2010;3(5):243-248. PMCID:PMC3062999 16. Rubio DM, Primack BA, Switzer GE, Bryce CL, Seltzer DL, W.N. K. A comprehensive career-success model for physician-scientists. Acad Med. 2011;86(12):1571-1576. PMCID:PMC3228877 17. ICRE. Research on Careers Workgroup. 2015.; www.icre.pitt.edu/research_careers.html. 18. Trochim W, Rubio D, Thomas V. Evaluation Guidelines for the Clinical and Translational Science Awards (CTSAs). Clin Transl Sci. 2013;6(4):303-309. PMCID:PMC3931516 19. Frechtling J, Rau K, Michie J, Miyaoka A, Spiegelman M. The CTSA National Evaluation Final Report. Rockville, MD: Westat.; 2012. References Cited Page 1468

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Training Award (TL1)
Project #
5TL1TR002368-02
Application #
9560957
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Jones, Patricia L
Project Start
2017-09-07
Project End
2022-06-30
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
2
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Kansas
Department
Neurology
Type
Schools of Medicine
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160