University of Florida Administrative Coordinating Center (ACC) and Field Center (Marco Pahor, MD), The proposed study will be conducted in the Department of Aging and Geriatric Research and the Institute of Aging (IOA) - Claude Pepper Older Americans Independence Center (OAIC). The research program of the IOA-OAIC focuses on the etiology, prevention and rehabilitation of cognitive and physical disability. The leading investigators in the IOA program have yrs of experience in NIH funded clinical research trials and the requisite skills to manage complex research enterprises. Marco Pahor, MD, PI of the proposed study, of the Administrative Coordinating Center and UF Field center PI, is Professor and Chair of the Department of Aging and Geriatric Research and Director of the UF Institute on Aging. He is a nationally and internationally known scientist in the areas of aging, disability and cardiovascular disease in population-based studies. He has over 27 years of experience in geriatrics, epidemiology and clinical trials, with special expertise in the area of physical disability in older populations. He has an excellent record of publications, leadership and administrative skills. He has authored or co-authored over 230 publications in leading peer reviewed journals in areas relevant to this application. He has extensive expertise in directing interdisciplinary research teams, such as LIFE-P, the UF and WFUHS OAIC and the UF Institute on Aging, and in planning, conducting and/or analyzing data from large NIH funded randomized controlled trials and epidemiologic studies in older populations, including HABC^9, WHAS10'15, EPESE16

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project--Cooperative Agreements (U01)
Project #
3U01AG022376-07S2
Application #
8535870
Study Section
Special Emphasis Panel (ZAG1-ZIJ-7)
Project Start
2003-09-30
Project End
2015-11-30
Budget Start
2012-09-01
Budget End
2012-11-30
Support Year
7
Fiscal Year
2012
Total Cost
$144,040
Indirect Cost
$45,719
Name
University of Florida
Department
Type
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Hughes, Timothy M; Sink, Kaycee M (2016) Hypertension and Its Role in Cognitive Function: Current Evidence and Challenges for the Future. Am J Hypertens 29:149-57
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Bann, David; Chen, Haiying; Bonell, Chris et al. (2016) Socioeconomic differences in the benefits of structured physical activity compared with health education on the prevention of major mobility disability in older adults: the LIFE study. J Epidemiol Community Health 70:930-3
Aubertin-Leheudre, Mylène; Anton, Stephen; Beavers, Daniel P et al. (2016) Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study. J Am Med Dir Assoc :
Rejeski, W Jack; Marsh, Anthony P; Brubaker, Peter H et al. (2016) Analysis and Interpretation of Accelerometry Data in Older Adults: The LIFE Study. J Gerontol A Biol Sci Med Sci 71:521-8
Gill, Thomas M; Pahor, Marco; Guralnik, Jack M et al. (2016) Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study). BMJ 352:i245
Groessl, Erik J; Kaplan, Robert M; Castro Sweet, Cynthia M et al. (2016) Cost-effectiveness of the LIFE Physical Activity Intervention for Older Adults at Increased Risk for Mobility Disability. J Gerontol A Biol Sci Med Sci 71:656-62
Marsh, Anthony P; Applegate, William B; Guralnik, Jack M et al. (2016) Hospitalizations During a Physical Activity Intervention in Older Adults at Risk of Mobility Disability: Analyses from the Lifestyle Interventions and Independence for Elders Randomized Clinical Trial. J Am Geriatr Soc 64:933-43
Kheirkhahan, Matin; Tudor-Locke, Catrine; Axtell, Robert et al. (2016) Actigraphy features for predicting mobility disability in older adults. Physiol Meas 37:1813-1833
Vaz Fragoso, Carlos A; Beavers, Daniel P; Anton, Stephen D et al. (2016) Effect of Structured Physical Activity on Respiratory Outcomes in Sedentary Elderly Adults with Mobility Limitations. J Am Geriatr Soc 64:501-9

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