Since the inception of WINS, the Bronx/Manhattan site has demonstrated both scientific and operational leadership nationally, and has provided the most data, with the largest retained cohort and the greatest participation in substudies. Dr. Anastos, the Bronx/Manhattan PI, has led the WIHS investigations of natural and treated history both before and after the introduction of HAART. In WIHS III the Bronx team has added to these accomplishments by broadening its scientific focus and markedly increasing its scientific productivity. This was achieved through development of a data analysis team, enhancement of our expertise in metabolic conditions of interest, the addition of a Co-PI with expertise in substance use and hepatitis C, continued support and flexibility for investigations of pathogenesis, and active management of data analysis and manuscript development. In WIHS III the Bronx has produced more papers than any other site in disease proa volume, completeness and quality;to develop further our local team's scientific productivity;to provide continued leadership in WIHS scientifically;and to develop further international collaborations in which WIHS can contribute to understanding of important parameters of the international epidemic in women. ????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AI035004-18
Application #
8014981
Study Section
Special Emphasis Panel (ZAI1-LW-A (S1))
Program Officer
Roe, Joanad'Arc C
Project Start
1993-08-01
Project End
2012-12-31
Budget Start
2011-01-01
Budget End
2011-12-31
Support Year
18
Fiscal Year
2011
Total Cost
$3,472,417
Indirect Cost
Name
Montefiore Medical Center (Bronx, NY)
Department
Type
DUNS #
041581026
City
New York
State
NY
Country
United States
Zip Code
10467
Taylor, Tonya N; Munoz-Plaza, Corrine E; Goparaju, Lakshmi et al. (2017) ""The Pleasure Is Better as I've Gotten Older"": Sexual Health, Sexuality, and Sexual Risk Behaviors Among Older Women Living With HIV. Arch Sex Behav 46:1137-1150
Burke-Miller, Jane K; Weber, Kathleen; Cohn, Susan E et al. (2017) Measurement of Neighborhood Context in an Urban Cohort of HIV-infected or at risk Low-Income Women. J Poverty 21:80-96
Price, Jennifer C; Ma, Yifei; Scherzer, Rebecca et al. (2017) Human immunodeficiency virus-infected and uninfected adults with non-genotype 3 hepatitis C virus have less hepatic steatosis than adults with neither infection. Hepatology 65:853-863
Reid, Michael; Ma, Yifei; Scherzer, Rebecca et al. (2017) Higher CD163 levels are associated with insulin resistance in hepatitis C virus-infected and HIV-infected adults. AIDS 31:385-393
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Haddad, Lisa B; Wall, Kristin M; Mehta, C Christina et al. (2017) Trends of and factors associated with live-birth and abortion rates among HIV-positive and HIV-negative women. Am J Obstet Gynecol 216:71.e1-71.e16
Kuniholm, Mark H; Liang, Hua; Anastos, Kathryn et al. (2017) Association of a 3' Untranslated Region Polymorphism in PCSK9 with HIV Viral Load and CD4+ Levels in HIV/Hepatitis C Virus Co-Infected Women. AIDS :
Nabi, Rafiq; Moldoveanu, Zina; Wei, Qing et al. (2017) Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy. PLoS One 12:e0180245
French, Audrey L; Martin, Jonathan W; Evans, Charlesnika T et al. (2017) Macrophage Activation and the Tumor Necrosis Factor Cascade in Hepatitis C Disease Progression Among HIV-Infected Women Participating in the Women's Interagency HIV Study. J Acquir Immune Defic Syndr 76:438-444
Butterfield, Tiffany R; Hanna, David B; Kaplan, Robert C et al. (2017) Increased glucose transporter-1 expression on intermediate monocytes from HIV-infected women with subclinical cardiovascular disease. AIDS 31:199-205

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