When smokers are hospitalized they quit smoking, either voluntarily or involuntarily. Most of them, however, go back to smoking soon after discharge. Research has shown that extended follow-up counseling post-discharge can help prevent relapse. However, it is difficult for hospitals to conduct extended follow up for patients after discharge. The proposed study aims to establish a practical model in which hospitals will work with a state quitline in the following manner: Hospital staff will conduct bedside counseling and then refer patients to the quitline. Quitline counselors will proactively call patients post-discharge and provide counseling up to 2 months. With the proposed project we intend to establish a practical model that lends itself to broader dissemination, while testing the effectiveness ofthe interventions with the rigor of a randomized design. We plan to demonstrate in a randomized trial the effects of two interventions, dispensing nicotine patches at discharge and providing proactive telephone counseling soon after discharge, on the long term quit rates of hospitalized smokers in a 2 x 2 factorial design. All eligible patients receive brief counseling from hospital staff. This is usual care. Study participants are randomly assigned into one ofthe four conditions: usual care, nicotine patch post discharge, telephone counseling post discharge, or both patch and counseling post discharge. It is hypothesized that the patch and counseling each has an independent effect and their combined effect is greater than that for either single intervention. We also intend to compare the cost-effectiveness ofthe interventions: patch alone, counseling alone, and combined interventions, against the usual care condition. Further, the proposed study will allow us to examine if a patient's medical diagnosis is a moderating factor for intervention effects such that patients with certain diagnoses benefit more from the interventions than patients with other diagnoses.

Public Health Relevance

, . - ,, ...,,. The hospital-quitline partnership model proposed to be tested in the study can help increase the number of hospitalized smokers to quit during their stay and remain quit post-discharge.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01CA159533-04
Application #
8470087
Study Section
Special Emphasis Panel (ZHL1-CSR-A (S1))
Program Officer
Grant, Yvonne F
Project Start
2010-09-27
Project End
2014-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
4
Fiscal Year
2013
Total Cost
$558,270
Indirect Cost
$98,822
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Scheuermann, Taneisha S; Richter, Kimber P; Rigotti, Nancy A et al. (2017) Accuracy of self-reported smoking abstinence in clinical trials of hospital-initiated smoking interventions. Addiction 112:2227-2236
Han, Benjamin H; Sherman, Scott E; Link, Alissa R et al. (2017) Comparison of the Substance Use Brief Screen (SUBS) to the AUDIT-C and ASSIST for detecting unhealthy alcohol and drug use in a population of hospitalized smokers. J Subst Abuse Treat 79:67-74
Sherman, Scott E; Link, Alissa R; Rogers, Erin S et al. (2016) Smoking-Cessation Interventions for Urban Hospital Patients: A Randomized Comparative Effectiveness Trial. Am J Prev Med 51:566-77
Cummins, Sharon E; Gamst, Anthony C; Brandstein, Kendra et al. (2016) Helping Hospitalized Smokers: A Factorial RCT of Nicotine Patches and Counseling. Am J Prev Med 51:578-86
Duffy, Sonia A; Cummins, Sharon E; Fellows, Jeffrey L et al. (2015) Fidelity monitoring across the seven studies in the Consortium of Hospitals Advancing Research on Tobacco (CHART). Tob Induc Dis 13:29
Riley, William T; Stevens, Victor J; Zhu, Shu-Hong et al. (2012) Overview of the Consortium of Hospitals Advancing Research on Tobacco (CHART). Trials 13:122
Harrington, Kathleen F; McDougal, Julie A; Pisu, Maria et al. (2012) Web-based smoking cessation intervention that transitions from inpatient to outpatient: study protocol for a randomized controlled trial. Trials 13:123
Fellows, Jeffrey L; Mularski, Richard; Waiwaiole, Lisa et al. (2012) Health and economic effects from linking bedside and outpatient tobacco cessation services for hospitalized smokers in two large hospitals: study protocol for a randomized controlled trial. Trials 13:129
Cummins, Sharon; Zhu, Shu-Hong; Gamst, Anthony et al. (2012) Nicotine patches and quitline counseling to help hospitalized smokers stay quit: study protocol for a randomized controlled trial. Trials 13:128