Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project--Cooperative Agreements (U01)
Project #
2U01DA020830-06
Application #
8127185
Study Section
Special Emphasis Panel (ZRG1-GGG-M (52))
Project Start
2010-08-01
Project End
2015-06-30
Budget Start
2010-08-01
Budget End
2011-06-30
Support Year
6
Fiscal Year
2010
Total Cost
$15,722
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Peng, Annie R; Schnoll, Robert; Hawk Jr, Larry W et al. (2018) Predicting smoking abstinence with biological and self-report measures of adherence to varenicline: Impact on pharmacogenetic trial outcomes. Drug Alcohol Depend 190:72-81
Taghavi, Taraneh; Novalen, Maria; Lerman, Caryn et al. (2018) A Comparison of Direct and Indirect Analytical Approaches to Measuring Total Nicotine Equivalents in Urine. Cancer Epidemiol Biomarkers Prev 27:882-891
Chenoweth, Meghan J; Ware, Jennifer J; Zhu, Andy Z X et al. (2018) Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences. Addiction 113:509-523
Tanner, Julie-Anne; Zhu, Andy Z; Claw, Katrina G et al. (2018) Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism. Pharmacogenet Genomics 28:7-16
Tanner, Julie-Anne; Prasad, Bhagwat; Claw, Katrina G et al. (2017) Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors. J Pharmacol Exp Ther 360:129-139
Goodman, Michelle S; Bridgman, Alanna C; Rabin, Rachel A et al. (2017) Differential effects of cannabis dependence on cortical inhibition in patients with schizophrenia and non-psychiatric controls. Brain Stimul 10:275-282
Schuit, Ewoud; Panagiotou, Orestis A; Munafò, Marcus R et al. (2017) Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers. Cochrane Database Syst Rev 9:CD011823
Chenoweth, Meghan J; Tyndale, Rachel F (2017) Pharmacogenetic Optimization of Smoking Cessation Treatment. Trends Pharmacol Sci 38:55-66
Barr, Mera S; Rajji, Tarek K; Zomorrodi, Reza et al. (2017) Impaired theta-gamma coupling during working memory performance in schizophrenia. Schizophr Res 189:104-110
Peng, Annie R; Morales, Mark; Wileyto, E Paul et al. (2017) Measures and predictors of varenicline adherence in the treatment of nicotine dependence. Addict Behav 75:122-129

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