To help address the needs of the NARMS retail meat surveillance project, as a surveillance site, we will sample packages of retail poultry, beef and pork from a randomly generated list of grocery stores in the surrounding area. Aliquots from each of eighty monthly packages will be cultured for pathogens, Salmonella and Campylobacter, along with two indicator bacteria, E. coli and Enterococcus, to address potential resistance mechanisms which may be transferred to pathogens. The resulting isolates will be shipped monthly to FDA for species and serotype confirmation and antimicrobial susceptibility testing, with duplicate isolates maintained in our culture collection. We expect to have successfully sampled 960 packages of retail beef, pork, and poultry during each 12-month study period. We expect that these efforts will help to provide critical data to not only track the current state of antimicrobial resistance among foodborne pathogens and indicator bacteria found in retail meat, but also to impact future FDA policy and regulations and monitor the success of actions and interventions. In addition to our contributions to the retail food surveillance program, as a NARMS retail food participating laboratory we will be available to support foodborne disease outbreak investigation. We already have a close working relationship with the Ohio Department of Health laboratory and the Ohio Department of Agriculture?s Animal Disease Diagnostic Laboratory. We will be available to directly support and extend their existing capability for outbreak investigation and sample process and testing. We also collaborate closely with the OSU Veterinary Medical Center Clinical Diagnostic Laboratory, which participates in the Vet-LIRN laboratory system, as does the ODA ADDL. Our existing close collaborations with these laboratories located in central Ohio will allow us to be effective as a NARMS retail food surveillance project laboratory, and to contribute to the support of other laboratories with related missions. An additional benefit of our participation in the NARMS retail food surveillance program is that we plan to engage multiple students from both the professional veterinary medicine and veterinary public health programs in this project. Students with an interest in food safety and antimicrobial resistance and stewardship will be able to gain laboratory experience and an understanding of the current antimicrobial resistance trends in foodborne pathogens. These students will then leave the university for careers in veterinary medicine and veterinary public health better trained in epidemiology, surveillance strategies, food safety and food microbiology, and public health practice.

Public Health Relevance

We propose to serve as a NARMS retail food surveillance collaborating laboratory. As a participant, we will routinely recover and contribute target pathogens and indicator bacteria to the NARMS surveillance program and support other agencies in Ohio investigating foodborne disease outbreaks. As part of the national NARMS network of laboratories, we will contribute to improved public health through the prevention of foodborne disease and reduced zoonotic transmission of antimicrobial resistant bacteria.

Agency
National Institute of Health (NIH)
Institute
Food and Drug Administration (FDA)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01FD006734-01
Application #
9924933
Study Section
Special Emphasis Panel (ZFD1)
Program Officer
Kabera, Claudine
Project Start
2019-08-15
Project End
2020-07-31
Budget Start
2019-08-15
Budget End
2020-07-31
Support Year
1
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Ohio State University
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
832127323
City
Columbus
State
OH
Country
United States
Zip Code
43210