National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Research Project--Cooperative Agreements (U01)
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Special Emphasis Panel (ZGM1)
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Texas A&M University
College Station
United States
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Buchko, Garry W; Echols, Nathaniel; Flynn, E Megan et al. (2017) Structural and Biophysical Characterization of the Mycobacterium tuberculosis Protein Rv0577, a Protein Associated with Neutral Red Staining of Virulent Tuberculosis Strains and Homologue of the Streptomyces coelicolor Protein KbpA. Biochemistry 56:4015-4027
Kieser, Karen J; Boutte, Cara C; Kester, Jemila C et al. (2015) Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria. PLoS Pathog 11:e1005010
Kieser, Karen J; Baranowski, Catherine; Chao, Michael C et al. (2015) Peptidoglycan synthesis in Mycobacterium tuberculosis is organized into networks with varying drug susceptibility. Proc Natl Acad Sci U S A 112:13087-92
Kieser, Karen J; Rubin, Eric J (2014) How sisters grow apart: mycobacterial growth and division. Nat Rev Microbiol 12:550-62
DeJesus, Michael A; Zhang, Yanjia J; Sassetti, Christopher M et al. (2013) Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries. Bioinformatics 29:695-703
Sureshan, Visaahini; Deshpande, Chandrika N; Boucher, Yan et al. (2013) Integron gene cassettes: a repository of novel protein folds with distinct interaction sites. PLoS One 8:e52934
Kim, Youngchang; Cunningham, Mark A; Mire, Joseph et al. (2013) NDM-1, the ultimate promiscuous enzyme: substrate recognition and catalytic mechanism. FASEB J 27:1917-27
Moraski, Garrett C; Markley, Lowell D; Cramer, Jeffrey et al. (2013) Advancement of Imidazo[1,2-a]pyridines with Improved Pharmacokinetics and Nanomolar Activity Against Mycobacterium tuberculosis. ACS Med Chem Lett 4:675-679
Ioerger, Thomas R; O'Malley, Theresa; Liao, Reiling et al. (2013) Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis. PLoS One 8:e75245
Chao, Michael C; Kieser, Karen J; Minami, Shoko et al. (2013) Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria. PLoS Pathog 9:e1003197

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