The University of South Florida Adolescent Medicine Trials Unit (USF AMTU) provides primary and specialty care, prevention services and access to clinical trials to HIV-infected and at-risk youth in the Tampa Bay area. To sustain and expand these services the USF AMTU proposes the following specific aims for this proposal: 1) to improve the health and function of HIV infected youth through the design and implementation of therapeutic and behavioral research trials, 2) to sustain and expand community relationships to further facilitate awareness of and access to HIV prevention and treatment resources for Tampa Bay area adolescents, particularly within high-risk social networks, and 3) to utilize the large geographical service area, and epidemiology of HIV in Tampa Bay to explore innovative approaches to expand and improve access to research trials, prevention programs, and clinical care. The objectives established support these aims. It is the intent of USF AMTU to continue to provide a seamless continuum of comprehensive care, address the mental health needs of those served, and support the emerging autonomy of HIV-infected youth. The USF AMTU will collaborate with the ATM leadership group to develop clinical trails that addressprimary, secondary, and tertiary HIV prevention and expand services that allow for the implementation of this broad research agenda. To support these efforts, the USFAMTU will continue to work toward building community capacity and enhancing relationships with its Connect to Protect partners. New initiatives will include connecting with traditionally hard-to-reach youth by utilizing peer educators, a mobile services unit, and outreach to youth service organizations. The USF AMTU has the experience and infrastructure to meet the challenges of recruiting and retaining youth into care and to clinical trials. The AMTU at USF responds to Health People 2010 goals that emphasize the need to address the disproportionate impact of HIV on African Americans and Hispanics. By supporting efforts to engage, recruit and retain youth of ethnic and racial minority cultures, the unit proactively works to reduce the incidences of HIV in these populations and improve the quality of life for those already infected

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HD040497-10
Application #
7845734
Study Section
Special Emphasis Panel (ZHD1-DRG-D (25))
Program Officer
Shirazi, Yasaman
Project Start
2001-04-15
Project End
2011-02-28
Budget Start
2010-03-01
Budget End
2011-02-28
Support Year
10
Fiscal Year
2010
Total Cost
$596,392
Indirect Cost
Name
University of South Florida
Department
Pediatrics
Type
Schools of Medicine
DUNS #
069687242
City
Tampa
State
FL
Country
United States
Zip Code
33612
Harper, Gary W; Tyler, April Timmons; Bruce, Douglas et al. (2016) Drugs, Sex, and Condoms: Identification and Interpretation of Race-Specific Cultural Messages Influencing Black Gay and Bisexual Young Men Living with HIV. Am J Community Psychol 58:463-476
Rudy, Bret J; Kapogiannis, Bill G; Worrell, Carol et al. (2015) Immune Reconstitution but Persistent Activation After 48 Weeks of Antiretroviral Therapy in Youth With Pre-Therapy CD4 >350 in ATN 061. J Acquir Immune Defic Syndr 69:52-60
Havens, Peter L; Hazra, Rohan; Stephensen, Charles B et al. (2014) Vitamin D3 supplementation increases fibroblast growth factor-23 in HIV-infected youths treated with tenofovir disoproxil fumarate. Antivir Ther 19:613-8
Harper, Gary W; Bruce, Douglas; Hosek, Sybil G et al. (2014) Resilience processes demonstrated by young gay and bisexual men living with HIV: implications for intervention. AIDS Patient Care STDS 28:666-76
Porter, Travis R; Li, Xuelin; Stephensen, Charles B et al. (2013) Genetic associations with 25-hydroxyvitamin D deficiency in HIV-1-infected youth: fine-mapping for the GC/DBP gene that encodes the vitamin D-binding protein. Front Genet 4:234
Harper, Gary W; Fernandez, Isabel M; Bruce, Douglas et al. (2013) The role of multiple identities in adherence to medical appointments among gay/bisexual male adolescents living with HIV. AIDS Behav 17:213-23
Lee, Sonia; Kapogiannis, Bill G; Flynn, Patricia M et al. (2013) Comprehension of a simplified assent form in a vaccine trial for adolescents. J Med Ethics 39:410-2
Havens, Peter L; Kiser, Jennifer J; Stephensen, Charles B et al. (2013) Association of higher plasma vitamin D binding protein and lower free calcitriol levels with tenofovir disoproxil fumarate use and plasma and intracellular tenofovir pharmacokinetics: cause of a functional vitamin D deficiency? Antimicrob Agents Chemother 57:5619-28
Harper, Gary W; Willard, Nancy; Ellen, Jonathan M et al. (2012) Connect to Protect®: utilizing community mobilization and structural change to prevent HIV infection among youth. J Prev Interv Community 40:81-6
Havens, Peter L; Mulligan, Kathleen; Hazra, Rohan et al. (2012) Serum 25-hydroxyvitamin D response to vitamin D3 supplementation 50,000 IU monthly in youth with HIV-1 infection. J Clin Endocrinol Metab 97:4004-13

Showing the most recent 10 out of 21 publications