The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATM) was formed in response to the needs of the unabated domestic HIV epidemic in youth. The Adolescent Medicine Leadership Group (AMLG) and ATM Coordinating Center (ACC) described in this application propose to continue to build on their scientific, administrative and experiential leadership in the ATM and together with the site personnel develop and implement the scientific agenda of the ATN for this next project period. The scientific and administrative leadership proposed here will continue to work toward maximizing quality, efficiency and productivity while incorporating responsiveness, flexibility, transparency and innovation in their work. Additionally, the ATN as a whole will continue to nurture and expand the collaborations that were established in the first project period with other federally funded networks and programs. The proposed ACC will continue its pivotal facilitating role in the functioning of the ATN. The AMLG is proposed to initiate this project period with three distinct scientific leadership groups, the Behavioral (BLG), Community Prevention (CPLG) and Therapeutic Leadership Groups (TLG), with complimentary expertise both within and across groups to provide the multidisciplinary approach needed to address issues in the populations of focus. The BLG will focus its agenda on both perinatally and behaviorally HIV infected youth and have identifed the following key areas for interventions: mental health, secondary prevention and risk reduction, needs of youth engaging in care including those acutely infected, and medication adherence. The CPLG will focus on continued development of a community based primary prevention infrastructure and interventions including biological interventions such as vaccines or microbicides. The agenda of the TLG uses a theoretical framework to identify key elements and approaches for an adolescent specific agenda for both perinatally and behaviorally infected youth. The scientific agenda of the leadership groups will be continually reviewed in the context of future developments and a flexible, adaptive approach to address new needs will continue to be a priority. The ATN as a whole remains the only federally funded network focused solely on the complex needs and issues of the HIV infected and at-risk youth at the epicenter of the domestic HIV epidemic.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Research Project--Cooperative Agreements (U01)
Project #
Application #
Study Section
Special Emphasis Panel (ZHD1-DRG-D (KW))
Program Officer
Shirazi, Yasaman
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Alabama Birmingham
Schools of Medicine
United States
Zip Code
Gamarel, Kristi E; Nelson, Kimberly M; Brown, Larry et al. (2017) The Usefulness of the CRAFFT in Screening for Problematic Drug and Alcohol Use Among Youth Living with HIV. AIDS Behav 21:1868-1877
Havens, Peter L; Stephensen, Charles B; Van Loan, Marta D et al. (2017) Decline in Bone Mass With Tenofovir Disoproxil Fumarate/Emtricitabine Is Associated With Hormonal Changes in the Absence of Renal Impairment When Used by HIV-Uninfected Adolescent Boys and Young Men for HIV Preexposure Prophylaxis. Clin Infect Dis 64:317-325
Reisner, Sari L; Jadwin-Cakmak, Laura; White Hughto, Jaclyn M et al. (2017) Characterizing the HIV Prevention and Care Continua in a Sample of Transgender Youth in the U.S. AIDS Behav 21:3312-3327
Gamarel, Kristi E; Nelson, Kimberly M; Stephenson, Rob et al. (2017) Anticipated HIV Stigma and Delays in Regular HIV Testing Behaviors Among Sexually-Active Young Gay, Bisexual, and Other Men Who Have Sex with Men and Transgender Women. AIDS Behav :
Hosek, Sybil G; Rudy, Bret; Landovitz, Raphael et al. (2017) An HIV Preexposure Prophylaxis Demonstration Project and Safety Study for Young MSM. J Acquir Immune Defic Syndr 74:21-29
Knopf, Amelia S; Ott, Mary A; Liu, Nancy et al. (2017) Minors' and Young Adults' Experiences of the Research Consent Process in a Phase II Safety Study of Pre-exposure Prophylaxis for HIV. J Adolesc Health 61:747-754
Knopf, Amelia S; Gilbert, Amy Lewis; Zimet, Gregory D et al. (2017) Moral conflict and competing duties in the initiation of a biomedical HIV prevention trial with minor adolescents. AJOB Empir Bioeth 8:145-152
Philbin, Morgan M; Tanner, Amanda E; Ma, Alice et al. (2017) Adolescent and Adult HIV Providers' Definitions of HIV-Infected Youths' Successful Transition to Adult Care in the United States. AIDS Patient Care STDS 31:421-427
Philbin, Morgan M; Tanner, Amanda E; DuVal, Anna et al. (2017) Understanding Care Linkage and Engagement Across 15 Adolescent Clinics: Provider Perspectives and Implications for Newly HIV-Infected Youth. AIDS Educ Prev 29:93-104
Miller, Robin Lin; Reed, Sarah J; Chiaramonte, Danielle et al. (2017) Structural and Community Change Outcomes of the Connect-to-Protect Coalitions: Trials and Triumphs Securing Adolescent Access to HIV Prevention, Testing, and Medical Care. Am J Community Psychol 60:199-214

Showing the most recent 10 out of 196 publications