The University of California at San Diego (UCSD) and Kaiser Permanente (KP) San Diego have participated as one of the 8 Clinical Centers in the Childhood Asthma Management Program (CAMP) Trial and CAMP Continuation Study (CAMPCS) since contract inception and award in 1991. For CAMP, our site randomized the required 122 children 5-12.years of age with mild to moderate asthma of which 40% were from ethnic minorities. Our research facilities are well equipped and conducive to perform all aspects of CAMPCS/2. The scientific portion of the study is part of the CAMPCS/2 multicenter proposal provided in the Washington University application. We at the UCSD/KP Clinical Center are willing to participate in the additional follow-up requested by this application and our track record as noted above is supportive of our ability to do so.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HL075415-03
Application #
6921376
Study Section
Clinical Trials Review Committee (CLTR)
Program Officer
Taggart, Virginia
Project Start
2003-09-30
Project End
2007-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
3
Fiscal Year
2005
Total Cost
$208,584
Indirect Cost
Name
University of California San Diego
Department
Pediatrics
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
McGeachie, Michael J; Yates, Katherine P; Zhou, Xiaobo et al. (2016) Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma. Am J Respir Crit Care Med 194:1465-1474
Park, Heung-Woo; Song, Woo-Jung; Chang, Yoon-Suk et al. (2016) Bronchodilator response following methacholine-induced bronchoconstriction predicts acute asthma exacerbations. Eur Respir J 48:104-14
Strunk, Robert C; Colvin, Ryan; Bacharier, Leonard B et al. (2015) Airway Obstruction Worsens in Young Adults with Asthma Who Become Obese. J Allergy Clin Immunol Pract 3:765-71.e2
Israel, Elliot; Lasky-Su, Jessica; Markezich, Amy et al. (2015) Genome-wide association study of short-acting ?2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3. Am J Respir Crit Care Med 191:530-7
Drye, Lea T; Casper, Anne S; Sternberg, Alice L et al. (2014) The transitioning from trials to extended follow-up studies. Clin Trials 11:635-47
Kelly, H William; Sternberg, Alice L; Lescher, Rachel et al. (2012) Effect of inhaled glucocorticoids in childhood on adult height. N Engl J Med 367:904-12
Tantisira, Kelan G; Damask, Amy; Szefler, Stanley J et al. (2012) Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus. Am J Respir Crit Care Med 185:1286-91
Wu, Ann Chen; Tantisira, Kelan; Li, Lingling et al. (2012) Effect of vitamin D and inhaled corticosteroid treatment on lung function in children. Am J Respir Crit Care Med 186:508-13
Wu, Ann Chen; Tantisira, Kelan; Li, Lingling et al. (2011) Predictors of symptoms are different from predictors of severe exacerbations from asthma in children. Chest 140:100-107
Raissy, Hengameh H; Sternberg, Alice L; Williams, Paul et al. (2010) Risk of cataracts in the Childhood Asthma Management Program Cohort. J Allergy Clin Immunol 126:389-92, 392.e1-4