Influenza and pneumococcal diseases cause thousands of needless deaths annually in the US, with greater mortality from these illnesses among underserved minorities. Better tools to improve adult vaccination rates, particularly in minority populations, are needed. A proven, but underutilized vaccination facilitator is a standing order program (SOP) in which an eligible patient can receive immunizations from nursing staff without a specific physician order. We developed a locally successful approach using tailored interventions that included SOPs, to increase vaccination rates in inner-city health centers and eliminate racial disparities. But this approach has not been updated recently nor tested nationally. Based on a decade of research on barriers and facilitators of vaccination, we believe that continued progress requires a combination of office system changes including SOPs and patient messages. From our national survey of primary care physicians about facilitators of and barriers to SOPs for adult immunization, we developed and pilot-tested an expert reviewed toolkit to facilitate SOP adoption and increase vaccination rates. We propose to enhance the toolkit with a Practice Transformation Dashboard, add Tdap, and expand related online training materials, shaped by input from the community and a national advisory board. The purpose of this enhancement process is to optimize the Reach, Adoption, Implementation and Effectiveness of the toolkit and training materials. Components include an immunization champion, feedback, motivation, and patient reminders. To rigorously test it, we will conduct an intensive randomized cluster trial of the """"""""4 Pillars SOP Toolkit"""""""" in primary care practice networks with EMRs, aiming to increase vaccination rates by 10%-20% and to eliminate racial disparity;evaluate the intervention using the RE-AIM framework, and determine Maintenance in subsequent years. Together with the AMA and using lessons learned from the trial, conduct a national before-and-after trial of the toolkit, using an intensity level consistent with AMA's practice-improvement CME and evaluate it, using the RE-AIM framework. Finally, we will determine the potential translatability and public health impact of the intervention through modeling and cost-effectiveness analyses.

Public Health Relevance

A proven, but underused, facilitator of immunization is a standing order program (SOP). We will revise an existing SOP toolkit and conduct an intensive randomized cluster trial of the SOP toolkit in primary care practice networks with EMRs. Using lessons learned from that trial, we plan a national before and improvement CME.

Agency
National Institute of Health (NIH)
Institute
National Center for Immunication and Respiratory Diseases (NCIRD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01IP000662-03
Application #
8708522
Study Section
Special Emphasis Panel (ZIP1)
Project Start
2012-09-01
Project End
2016-08-31
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Family Medicine
Type
Schools of Medicine
DUNS #
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Wateska, Angela R; Nowalk, Mary Patricia; Zimmerman, Richard K et al. (2018) Cost-effectiveness of increasing vaccination in high-risk adults aged 18-64 Years: a model-based decision analysis. BMC Infect Dis 18:52
Hawk, Mary; Nowalk, Mary Patricia; Moehling, Krissy K et al. (2017) Using a Mixed Methods Approach to Examine Practice Characteristics Associated With Implementation of an Adult Immunization Intervention Using the 4 Pillars Practice Transformation Program. J Healthc Qual 39:153-167
Nowalk, Mary Patricia; Moehling, Krissy K; Zhang, Song et al. (2017) Using the 4 Pillars to increase vaccination among high-risk adults: who benefits? Am J Manag Care 23:651-655
Smith, Kenneth J; Zimmerman, Richard K; Nowalk, Mary Patricia et al. (2017) Cost-Effectiveness of the 4 Pillars Practice Transformation Program to Improve Vaccination of Adults Aged 65 and Older. J Am Geriatr Soc 65:763-768
Zimmerman, Richard K; Brown, Anthony E; Pavlik, Valory N et al. (2017) Using the 4 Pillars Practice Transformation Program to Increase Pneumococcal Immunizations for Older Adults: A Cluster-Randomized Trial. J Am Geriatr Soc 65:114-122
Nowalk, Mary Patricia; Lin, Chyongchiou J; Pavlik, Valory N et al. (2016) Using the 4 Pillars™ Practice Transformation Program to increase adult Tdap immunization in a randomized controlled cluster trial. Vaccine 34:5026-5033
Lin, Chyongchiou J; Nowalk, Mary Patricia; Pavlik, Valory N et al. (2016) Using the 4 pillars™ practice transformation program to increase adult influenza vaccination and reduce missed opportunities in a randomized cluster trial. BMC Infect Dis 16:623
Zimmerman, Richard K (2014) Increasing engagement of clinicians in adult immunizations: reflections on a decade and a half of research. Vaccine 32:7040-2