The University of Miami's South Florida Center for Reducing Health Disparities (SUCCESS) aims to improve the health of South Florida's most vulnerable populations through collaborative, participatory research. Our primary focus has been to improve early detection and prevention of diseases that disproportionately affect communities, disenfranchised from the formal healthcare system. Towards this end, we have tested the effectiveness of multiple Community Health Worker (CHW)-led interventions to improve screening uptake for four priority health conditions: HIV, Hepatitis C, Colorectal Cancer (CRC), and cervical cancer. However, a major limitation of all such projects is that each has existed as distinct, standalone initiative targeting a specific community and/or individuals who meet narrow eligibility criteria. The current proposal will address this gap. We propose to develop and implement a clinical trial that offers screening for all four health conditions in a no-clinical setting, circumventing known structural and access barriers to care. Our partners in this application are our longstanding collaborators: the Health Choice Network- a consortium of Federally Qualified Health Centers (FQHCs), and the Center for Haitian Studies. Based on their input, we propose a pragmatic trial of 900 people ages 50-65 who self-identify as Hispanic, Haitian, and/or African and have not been appropriately screened for the aforementioned diseases of interest.
Our specific aim i s to determine whether a CHW led intervention, which provides innovative, home based screening increases uptake among medically underserved individuals who are in need of at least of these tests. This multi-modality approach will use oral swabs for HIV, finger stick testing for Hepatitis C, Fecal Immunochemical Testing (FIT) for CRC, and self- sampling for Human Papilloma Virus, the primary cause of cervical cancer. The proposed pragmatic trial, grounded in the tenets of community-based participatory research (CBPR), will help identify optimal strategies for delivering prevention services to medically-vulnerable population sub-groups. Our study testing innovative, cost sensitive approaches will help inform health reform strategies that increasingly prioritize population health and precision medicine.

Public Health Relevance

Minority groups suffer disproportionately from conditions such as HIV, Hepatitis C, colorectal and cervical cancer. Strategies that can increase rates of screening for these conditions can help narrow such disparities. We propose a study in which community health workers use recent advances in home testing technology to see if having these screenings services done at home leads to more screenings than simply referring persons to more traditional medical care.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01MD010614-03
Application #
9405039
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Das, Rina
Project Start
2016-05-19
Project End
2020-12-31
Budget Start
2018-01-01
Budget End
2018-12-31
Support Year
3
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
052780918
City
Coral Gables
State
FL
Country
United States
Zip Code
33146
Kenya, Sonjia; Lebron, Cynthia Nicole; Chang, Aileen Yu Hen et al. (2015) A profile of Latinos with poorly controlled diabetes in South Florida. J Community Hosp Intern Med Perspect 5:26586
Kenya, Sonjia; Carrasquillo, Olveen; Fatil, Marie et al. (2015) Human Papilloma Virus and Cervical Cancer Education Needs among HIV-Positive Haitian Women in Miami. Womens Health Issues 25:262-6
H├ębert, James R; Braun, Kathryn L; Meade, Cathy D et al. (2015) Community-Based Participatory Research Adds Value to the National Cancer Institute's Research Portfolio. Prog Community Health Partnersh 9 Suppl:1-4
Carrasquillo, Olveen; McCann, Sheila; Amofah, Antony et al. (2014) Rationale and design of the research project of the South Florida Center for the Reduction of Cancer Health Disparities (SUCCESS): study protocol for a randomized controlled trial. Trials 15:299
Marcus, Erin N; Koru-Sengul, Tulay; Miao, Feng et al. (2014) How do breast imaging centers communicate results to women with limited English proficiency and other barriers to care? J Immigr Minor Health 16:401-8
McKenzie, Nathalie Dauphin; Kobetz, Erin N; Ganjei-Azar, Parvin et al. (2014) HPV in HIV-Infected Women: Implications for Primary Prevention. Front Oncol 4:179
Kobetz, Erin; Kish, Jonathan K; Campos, Nicole G et al. (2012) Burden of Human Papillomavirus among Haitian Immigrants in Miami, Florida: Community-Based Participatory Research in Action. J Oncol 2012:728397