In this MARI application, we propose to develop and pilot test an intervention to improve the science of treatment as prevention (TasP) and pre-exposure prophylaxis (PrEP) uptake as a public health strategy to decrease new HIV infections among Black/African American and Hispanic/Latino MSM. The proposed research uses a 3-phase study design to address our proposed Specific Aims. First, we will use focus groups to gather feedback on our existing interactive Men2MenRI website that was developed for and by predominately White MSM in Rhode Island that includes information on TasP/PrEP, as well as other health and wellness topics to make it more culturally-tailored for Black/African American and Hispanic/Latino MSM. Second, we will use cognitive interviewing techniques to develop and assess the acceptability of Information- Motivation-Behavioral (IMB)/Social Cognitive Theory (SCT)-grounded social media message content designed to motivate and encourage access to our newly developed and culturally-tailored interactive website. Third, we will pilot test a two-arm trial comparing the combination of sending IMB/SCT-guided messages plus the newly developed and culturally-tailored interactive website (active arm) to the website alone (control arm) to examine whether the combination approach will: 1) increase TasP/PreP uptake (primary outcome); 2) increase knowledge of, more favorable attitudes toward, and increase behavioral intentions of TasP and PrEP use among Black/African American and Hispanic Latino MSM (secondary outcome); and 3) decrease sexual-risk behaviors (exploratory outcome). The proposed study is innovative in the use of a combination approach to TasP/PrEP uptake that leverages advances in social media as a platform for motivating behavior change.

Public Health Relevance

Public Health Relevancy This project has the potential to improve the implementation science of TasP/PrEP uptake as a public health strategy for reducing new HIV infections in the United States. We will develop and pilot test an intervention that combines messages sent over social media plus a newly developed interactive website specifically developed by and for Black/African American and Hispanic/Latino MSM to encourage TasP/PrEP use. Findings from this research can guide policy guidelines and recommendations for TasP/PrEP uptake for high-risk groups.

Agency
National Institute of Health (NIH)
Institute
National Center for HIV, Viral Hepatitis, STDS and Tb Prevention (NCHHSTP)
Type
Research Project--Cooperative Agreements (U01)
Project #
7U01PS005117-02
Application #
9325622
Study Section
Special Emphasis Panel (ZPS1-GCA (22))
Project Start
2016-05-01
Project End
2020-04-30
Budget Start
2016-08-01
Budget End
2017-04-30
Support Year
2
Fiscal Year
2016
Total Cost
$257,731
Indirect Cost
Name
Brown University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
001785542
City
Providence
State
RI
Country
United States
Zip Code
02912