The University of New Mexico Cancer Research and Treatment Center (UNM-CTRC) has participated in SWOG studies since its founding in 1970. The clinical faculty includes 10 medical oncologists in the Department of Medicine. Other clinical specialties that also participate in SWOG studies include radiation oncology, surgery, urology, and gynecologic oncology. Drs. Foucar, McConnell and Willman in the Department of Pathology contribute important core service functions. Through her position as chair of the Leukemia Biology Committee, Dr. Willman in particular has led SWOG's development of basic biology integrated with clinical trials in leukemia. Dr. Laurence Elias has a longstanding record of productivity in experimental therapeutics, and he has conducted a number of pilot studies at the University of New Mexico that have been incorporated into SWOG for further testing. He was the principal coordinator of six clinical protocols within the Group during the past grant period. Seven other UNM investigators have been principal or co-coordinators on 23 SWOG protocols during this period. Six research nurses, five at the CTRC clinic and one at the VA, screen patients for enrollment on study. Thirty-eight percent of New Mexico's citizens are Hispanic and 9 percent are Native Americans. A substantial portion of the population lives in isolated rural communities. Most minority citizens are young (median age, 20) and poor (New Mexico ranks 49th in per-capita income). The CTRC clinic staff is bilingual and can provide culturally sensitive counseling to patients who speak only Spanish or a Native American language.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
2U10CA012213-27
Application #
2451746
Study Section
Subcommittee G - Education (NCI)
Program Officer
Kaplan, Richard S
Project Start
1978-01-01
Project End
2002-12-31
Budget Start
1998-06-11
Budget End
1998-12-31
Support Year
27
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of New Mexico
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Cesano, Alessandra; Willman, Cheryl L; Kopecky, Kenneth J et al. (2015) Cell signaling-based classifier predicts response to induction therapy in elderly patients with acute myeloid leukemia. PLoS One 10:e0118485
Ostronoff, Fabiana; Othus, Megan; Lazenby, Michelle et al. (2015) Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report. J Clin Oncol 33:1157-64
Carson 3rd, William E; Unger, Joseph M; Sosman, Jeffrey A et al. (2014) Adjuvant vaccine immunotherapy of resected, clinically node-negative melanoma: long-term outcome and impact of HLA class I antigen expression on overall survival. Cancer Immunol Res 2:981-7
Douer, Dan; Zickl, Lynette N; Schiffer, Charles A et al. (2013) All-trans retinoic acid and late relapses in acute promyelocytic leukemia: very long-term follow-up of the North American Intergroup Study I0129. Leuk Res 37:795-801
Ostronoff, F; Othus, M; Ho, P A et al. (2013) Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with acute myeloid leukemia: a SWOG report. Leukemia 27:238-41
Tangen, Catherine M; Hussain, Maha H A; Higano, Celestia S et al. (2012) Improved overall survival trends of men with newly diagnosed M1 prostate cancer: a SWOG phase III trial experience (S8494, S8894 and S9346). J Urol 188:1164-9
Sosman, Jeffrey A; Moon, James; Tuthill, Ralph J et al. (2011) A phase 2 trial of complete resection for stage IV melanoma: results of Southwest Oncology Group Clinical Trial S9430. Cancer 117:4740-06
Ho, Phoenix A; Kopecky, Kenneth J; Alonzo, Todd A et al. (2011) Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG. Blood 118:4561-6
Chu, David Z J; Hussey, Michael A; Alberts, David S et al. (2011) Colorectal Chemoprevention Pilot Study (SWOG-9041), randomized and placebo controlled: the importance of multiple luminal lesions. Clin Colorectal Cancer 10:310-6
Tallman, Martin S; Kim, Haesook T; Montesinos, Pau et al. (2010) Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group. Blood 116:5650-9

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