The specific objective of this application is to continue to provide patients in our region access to the National Cancer Institute treatment and cancer prevention/control research protocols through the Community Cancer Oncology Program (CCOP). A primary goal of the Sioux Community Cancer Consortium (SCCC) is to achieve 150 cancer treatment credits and 90 new cancer control credits per year. We will also achieve 75 follow up credits in the cancer control category per year. [Total credits/year = 150 treatment, 165 cancer control.] These are realistic numbers based on the past accomplishments of the SCCC. The SCCC is a two component;two affiliate community based clinical cancer research organization. The two major components are Sanford Oncology in Sioux Falls, SD and Siouxland Hematology -Oncology Associates in Sioux City, Iowa. There two components are a mere 90 miles apart on Interstate 29 in the rural Midwest. The Sanford component has two affiliate sites - Avera Cancer Institute (Avera Medical Oncology/Hematology and Avera Hematology and Transplant) Sioux Falls, SD and Front Range Cancer Specialists in Fort Collins, Colorado. The Sioux City, Iowa, component has a number of outreach sites. The geographic catchment area for the SCCC covers approximately 105,000 square miles in SE South Dakota, SW Minnesota, NW Iowa and NE Nebraska. The Fort Collins catchment area covers approximately 35,000 square miles. The SCCC primary research base is the North Central Cancer Treatment Group (NCCTG). The SCCC is a secondary CCOP of the Eastern Cooperative Oncology Group (ECOG). The SCCC is a member of the National Surgical Adjuvant Breast and Bowel Project (NSABP). We participated in the NSABP initial Breast Cancer Prevention Trial (BCPT), as well as in the STAR trial. We participated in the initial SWOG Protstate Cancer Prevention Trial (PCPT) as well as in the SELECT trial. We continue to follow all these prevention participants. We participate in CTSU studies. The SCCC research team is dedicated to excellence in protocol administration and data management. The SCCC consists of 23 core investigators in medical . oncology, radiation oncology, and surgery. There are a number of supporting physicians in other medical disciplines.
The Sioux Community Cancer Consortium(SCCC)- CCOP project provides access to NCI cancer treatment and cancer prevention/control trials for patients in our region. The SCCC provides education and resources for physicians in our region regarding clinical cancer treatment trials and cancer prevention/control trials. The SCCC will continue to address the participation of women and minorities in NCI cancer trials.
|Huang, Jocelin; Nair, Suresh G; Mahoney, Michelle R et al. (2014) Comparison of FOLFIRI with or without cetuximab in patients with resected stage III colon cancer; NCCTG (Alliance) intergroup trial N0147. Clin Colorectal Cancer 13:100-9|
|Jaeckle, Kurt A; Ballman, Karla V; Giannini, Caterina et al. (2010) Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM. J Neurooncol 99:73-80|
|Opyrchal, Mateusz; Aderca, Ileana; Galanis, Evanthia (2009) Phase I clinical trial of locoregional administration of the oncolytic adenovirus ONYX-015 in combination with mitomycin-C, doxorubicin, and cisplatin chemotherapy in patients with advanced sarcomas. Methods Mol Biol 542:705-17|
|Santisteban, Marta; Buckner, Jan C; Reid, Joel M et al. (2009) Phase II trial of two different irinotecan schedules with pharmacokinetic analysis in patients with recurrent glioma: North Central Cancer Treatment Group results. J Neurooncol 92:165-75|
|Garces, Yolanda I; Okuno, Scott H; Schild, Steven E et al. (2007) Phase I North Central Cancer Treatment Group Trial-N9923 of escalating doses of twice-daily thoracic radiation therapy with amifostine and with alternating chemotherapy in limited stage small-cell lung cancer. Int J Radiat Oncol Biol Phys 67:995-1001|