The Upstate Carolina Community Clinical Oncology Program (UC-CCOP) has achieved a national reputation for excellence in community cancer care through its 28-year participation in programs of the National Cancer Institute. The UC-CCOP is one of 27 CCOPs that have been continuously funded since 1983. The UC-CCOP seeks to meet the community's need for novel and relevant studies of promising therapeutic and treatment modalities and cancer control and prevention research. The ongoing mission of the UC-CCOP is to assure that every person in the region served is provided an opportunity for participation in a national cancer prevention and/or treatment clinical trial. UC-CCOP strives to provide education about cancer and all NCI clinical trials programs. This grant application encompasses and defines clear objectives of an ever-expanding vision for the UC-CCOP. Goals for this grant cycle: ?Increase patient accrual to cancer treatment, prevention and control clinicl trials sponsored by the NCI and CCOP research bases. ?Increase the number of clinical trial participants from underrepresented populations through continued collaboration with the NCI and proposed strategic initiatives. ?Increase the portfolio of biospecimen/translational clinical trials in collaboration and partnership with participating research bases and the NCI. ?Expand availability of survivorship clinical trials. ?Maintain high-quality data management. ?Improve early phase trial participation through infrastructure and process development. Key strategies to achieving the above goals include (1) expanding the """"""""multidisciplinary approach"""""""" to foster the UC-CCOP and Gibbs Cancer Center patient navigator program in order to determine the patient navigator's potential role in and beneficial effects on clinical trial accrual and successful completion of clinical trials, (2) partnering with the NCI to be a pilot site to grow translational research in the community, and (3) utilizing our Minority and Outreach Navigators to strengthen and further develop partnerships with community organizations.

Public Health Relevance

The UC-CCOP continues to provide the community access to the most up-to-date clinical trials available through the NCI. This partnership allows us the opportunity to expand clinical trial accrual in a community-based setting, in turn providing state-of-the-art treatment regardless of race, gender, ethnicity or age.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA035119-29
Application #
8511573
Study Section
Special Emphasis Panel (ZCA1-SRLB-E (J1))
Program Officer
Mccaskill-Stevens, Worta J
Project Start
1983-09-01
Project End
2015-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
29
Fiscal Year
2013
Total Cost
$1,065,000
Indirect Cost
$229,017
Name
Spartanburg Regional Medical Center
Department
Type
DUNS #
052072048
City
Spartanburg
State
SC
Country
United States
Zip Code
29303
Barton, Debra L; Sloan, Jeff A; Shuster, Lynne T et al. (2018) Evaluating the efficacy of vaginal dehydroepiandosterone for vaginal symptoms in postmenopausal cancer survivors: NCCTG N10C1 (Alliance). Support Care Cancer 26:643-650
West, Howard L; Moon, James; Wozniak, Antoinette J et al. (2018) Paired Phase II Studies of Erlotinib/Bevacizumab for Advanced Bronchioloalveolar Carcinoma or Never Smokers With Advanced Non-Small-cell Lung Cancer: SWOG S0635 and S0636 Trials. Clin Lung Cancer 19:84-92
Hussain, Maha; Tangen, Catherine M; Thompson Jr, Ian M et al. (2018) Phase III Intergroup Trial of Adjuvant Androgen Deprivation With or Without Mitoxantrone Plus Prednisone in Patients With High-Risk Prostate Cancer After Radical Prostatectomy: SWOG S9921. J Clin Oncol 36:1498-1504
Persky, Daniel O; Li, Hongli; Rimsza, Lisa M et al. (2018) A phase I/II trial of vorinostat (SAHA) in combination with rituximab-CHOP in patients with newly diagnosed advanced stage diffuse large B-cell lymphoma (DLBCL): SWOG S0806. Am J Hematol 93:486-493
Danilov, Alexey V; Li, Hongli; Press, Oliver W et al. (2017) Feasibility of interim positron emission tomography (PET)-adapted therapy in HIV-positive patients with advanced Hodgkin lymphoma (HL): a sub-analysis of SWOG S0816 Phase 2 trial. Leuk Lymphoma 58:461-465
Liu, Xiaonan; Li, Jing; Schild, Steven E et al. (2017) Statins and Metformin Use Is Associated with Lower PSA Levels in Prostate Cancer Patients Presenting for Radiation Therapy. J Cancer Ther 8:73-85
Moinpour, Carol M; Unger, Joseph M; Ganz, Patricia A et al. (2017) Seven-year follow-up for energy/vitality outcomes in early stage Hodgkin's disease patients treated with subtotal lymphoid irradiation versus chemotherapy plus radiation: SWOG S9133 and its QOL companion study, S9208. J Cancer Surviv 11:32-40
Heinrich, Michael C; Rankin, Cathryn; Blanke, Charles D et al. (2017) Correlation of Long-term Results of Imatinib in Advanced Gastrointestinal Stromal Tumors With Next-Generation Sequencing Results: Analysis of Phase 3 SWOG Intergroup Trial S0033. JAMA Oncol 3:944-952
Sio, Terence T; Atherton, Pamela J; Birckhead, Brandon J et al. (2016) Repeated measures analyses of dermatitis symptom evolution in breast cancer patients receiving radiotherapy in a phase 3 randomized trial of mometasone furoate vs placebo (N06C4 [alliance]). Support Care Cancer 24:3847-55
Nahleh, Z A; Barlow, W E; Hayes, D F et al. (2016) SWOG S0800 (NCI CDR0000636131): addition of bevacizumab to neoadjuvant nab-paclitaxel with dose-dense doxorubicin and cyclophosphamide improves pathologic complete response (pCR) rates in inflammatory or locally advanced breast cancer. Breast Cancer Res Treat 158:485-95

Showing the most recent 10 out of 202 publications