This multiple-Pi, multiple-institution application for the competing renewal of the Pacific Northwest (PNW) Node of the NIDA Clinical Trials Network, submitted jointly by the University of Washington and Washington State University (WSU), has the primary aim of continuing the Node's active support of the CTN's mission to "improve the quality of drug abuse treatment throughout the country using science as the vehicle", to conduct studies of the therapeutic effect of behavioral, pharmacological, and combined/integrated treatment interventions in rigorous, multi-site clinical trials to determine effectiveness across a broad range of community-based treatment settings and diversified patient populations, and to ensure the transfer of research results to physicians, clinicians, providers, policy makers, and patients. To meet these objectives, the PNW Node proposes to: 'Maintain/expand the effective, bidirectional partnerships among researchers, substance abuse treatment and healthcare providers, and policy makers that predate our entry into the CTN;'Maintain/expand our highly successful, well-established treatment research infrastructure;'Expand the Node's geographical reach, working with the CTSA-funded Institute of Translational Health Sciences (ITHS), to include the WWAMI region (Washington, Wyoming, Alaska, Montana, and Idaho);'Expand the Node's ethnic and demographic diversity by broadening the types of affiliated programs, expanding our focus on American Indians/Alaska Natives, and concentrating on rural communities/programs through our partnership with WSU's Program of Excellence on Rural Mental Health and Substance Abuse Treatment;Enhance the Node's capacity to conduct trials and respond more rapidly to shifting and emerging public health priorities by adding a number of larger, highly research-experienced, medically and psychiatrically focused partner organizations to complement our affiliated community-based substance abuse treatment programs;'Augment the clinical research expertise of the Node by adding a number of new affiliated Investigators;'Expand the Node's network of dissemination partners in order to provide research translation and training to a wider geographic and professional audience of providers, especially in primary care and rural settings. This new structure will allow us to capitalize on progress we have made and will enable us to continue to make significant contributions to the CTN's mission in the future.
Substance abuse is a major public health problem. Working with partnering community-based substance abuse, psychiatric, medical, and dissemination programs, the PNW Node contributes significantly to the CTN's developmental, evaluative, and translational research process to identify and disseminate empirically supported behavioral, pharmacological, and combined/integrated interventions for adoption by CTPs (Community Treatment Programs).
|Campbell, Aimee N C; Brooks, Audrey J; Pavlicova, Martina et al. (2016) Barriers to Condom Use: Results for Men and Women Enrolled in HIV Risk Reduction Trials in Outpatient Drug Treatment. J HIV AIDS Soc Serv 15:130-146|
|McPherson, Sterling; Brooks, Olivia; Barbosa-Leiker, Celestina et al. (2016) Examining Longitudinal Stimulant Use and Treatment Attendance as Parallel Outcomes in Two Contingency Management Randomized Clinical Trials. J Subst Abuse Treat 61:18-25|
|Murphy, Sean M; Campbell, Aimee N C; Ghitza, Udi E et al. (2016) Cost-effectiveness of an internet-delivered treatment for substance abuse: Data from a multisite randomized controlled trial. Drug Alcohol Depend 161:119-26|
|Miguel, AndrÃ© Q C; Madruga, Clarice S; Cogo-Moreira, Hugo et al. (2016) Contingency management is effective in promoting abstinence and retention in treatment among crack cocaine users in Brazil: A randomized controlled trial. Psychol Addict Behav 30:536-543|
|Adinoff, Bryon; Carmody, Thomas J; Walker, Robrina et al. (2016) Decision-making processes as predictors of relapse and subsequent use in stimulant-dependent patients. Am J Drug Alcohol Abuse 42:88-97|
|Hartzler, Bryan; Garrett, Sharon (2016) Interest and preferences for contingency management design among addiction treatment clientele. Am J Drug Alcohol Abuse 42:287-95|
|Mamey, Mary Rose; Barbosa-Leiker, Celestina; McPherson, Sterling et al. (2015) An application of analyzing the trajectories of two disorders: A parallel piecewise growth model of substance use and attention-deficit/hyperactivity disorder. Exp Clin Psychopharmacol 23:422-7|
|Rosa, Carmen; Campbell, Aimee N C; Miele, Gloria M et al. (2015) Using e-technologies in clinical trials. Contemp Clin Trials 45:41-54|
|Campbell, Aimee N C; Nunes, Edward V; Pavlicova, Martina et al. (2015) Gender-based Outcomes and Acceptability of a Computer-assisted Psychosocial Intervention for Substance Use Disorders. J Subst Abuse Treat 53:9-15|
|Saxon, Andrew J (2015) Commentary on Burns et al. (2015): retention in buprenorphine treatment. Addiction 110:656-7|
Showing the most recent 10 out of 108 publications