Vision disorders such as strabismus, amblyopia and refractive error are the leading causes of handicapping conditions in childhood. Over the past decade, there is an increasing amount of evidence that suggest that early diagnosis and treatment of these ocular disorders can result in beneficial outcomes. Indeed, early detection and treatment is critical because it can decrease the burden of visual impairment on the child, her/his family and the society at large. This has lead to widespread interest in screening programs. However, despite the wealth of knowledge regarding early treatment, very little evidence exists on the prevalence of vision disorders in children. Additionally, almost no evidence exists on minority populations. The primary objective of this study, the Multi-Ethnic Pediatric Eye Disease Study (MEPEDS) is to improve our understanding of the magnitude and causes of ocular disease problems in population based samples of African-American, Latino and Non-Hispanic White children in the United States. A population-based sample of three thousand children from each of the three ethnic/racial groups will undergo a comprehensive eye examination to determine the prevalence of refractive error, strabismus and amblyopia. MEPEDS will also be studying selected demographic, biological and behavioral risk factors associated with these diseases and the consequences of these diseases from a health related quality of life perspective.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10EY014472-09
Application #
7777287
Study Section
Special Emphasis Panel (ZEY1-VSN (03))
Program Officer
Kurinij, Natalie
Project Start
2002-09-30
Project End
2012-01-31
Budget Start
2010-02-01
Budget End
2011-01-31
Support Year
9
Fiscal Year
2010
Total Cost
$2,956,087
Indirect Cost
Name
University of Southern California
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Xie, John Z; Tarczy-Hornoch, Kristina; Lin, Jesse et al. (2014) Color vision deficiency in preschool children: the multi-ethnic pediatric eye disease study. Ophthalmology 121:1469-74
Tarczy-Hornoch, Kristina; Cotter, Susan A; Borchert, Mark et al. (2013) Prevalence and causes of visual impairment in Asian and non-Hispanic white preschool children: Multi-ethnic Pediatric Eye Disease Study. Ophthalmology 120:1220-6
McKean-Cowdin, Roberta; Cotter, Susan A; Tarczy-Hornoch, Kristina et al. (2013) Prevalence of amblyopia or strabismus in asian and non-Hispanic white preschool children: multi-ethnic pediatric eye disease study. Ophthalmology 120:2117-24
Wen, Ge; Tarczy-Hornoch, Kristina; McKean-Cowdin, Roberta et al. (2013) Prevalence of myopia, hyperopia, and astigmatism in non-Hispanic white and Asian children: multi-ethnic pediatric eye disease study. Ophthalmology 120:2109-16
Varma, Rohit; McKean-Cowdin, Roberta; Vitale, Susan et al. (2013) Vision assessment using the NIH Toolbox. Neurology 80:S37-40
Wen, Ge; McKean-Cowdin, Roberta; Varma, Rohit et al. (2011) General health-related quality of life in preschool children with strabismus or amblyopia. Ophthalmology 118:574-80
Fozailoff, Arezoo; Tarczy-Hornoch, Kristina; Cotter, Susan et al. (2011) Prevalence of astigmatism in 6- to 72-month-old African American and Hispanic children: the Multi-ethnic Pediatric Eye Disease Study. Ophthalmology 118:284-93
Cotter, Susan A; Varma, Rohit; Tarczy-Hornoch, Kristina et al. (2011) Risk factors associated with childhood strabismus: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. Ophthalmology 118:2251-61
Tarczy-Hornoch, Kristina; Varma, Rohit; Cotter, Susan A et al. (2011) Risk factors for decreased visual acuity in preschool children: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. Ophthalmology 118:2262-73
Borchert, Mark S; Varma, Rohit; Cotter, Susan A et al. (2011) Risk factors for hyperopia and myopia in preschool children the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. Ophthalmology 118:1966-73

Showing the most recent 10 out of 21 publications