Under a cooperative agreement with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Christiana Care Health Services, Inc. (CCHS) and its partner, Jawaharlal Nehru Medical College (JNMC) of KLE. University, have the long-term objective of continued participation in the Global Network for Women's and Children's Health Research and continued collaboration in the operation of the CCHS-JNMC Research Unit. As a member of a multicenter international research network, the CCHS-JNMC Research Unit will conduct randomized clinical trials and intervention studies focused on reducing major risks to maternal, neonatal, infant, and early childhood health in low and lower-middle income countries. In collaboration with other Global Network participants, CCHS and JNMC will work to strengthen the Global Network research infrastructure, to increase the capacity for women's and children's health research, and to expand scientific knowledge that will lead to improved health practices and outcomes for women, infants, and children.
Specific aims of the CCHS-JNMC Research Unit during the next five-year Global Network funding cycle include: ?To provide for continued growth and development of the CCHS-JNMC RU which oversees the women's and children's health research program based at JNMC in Belgaum, Karnataka India, and to ensure sustainability of the research infrastructure at JNMC, integrated within the larger KLE University, and extending into surrounding districts served by JNMC and the University; ?To strengthen the Global Network and its role in international collaborative research by participating in creation of a significant GN research agenda and designing, developing, obtaining support for implementation, and conducting multiple, common research protocols which address the major causes of morbidity and mortality in women and young children in the developing world; ?To identify and address gaps in maternal and child research and, with other GN participants, to collaboratively implement and evaluate promising health interventions, formative and translational studies, including implementation research;and to disseminate findings.

Public Health Relevance

Continued participation in Global Network activities will strengthen the research capabilities of the CCHSJNMC Research Unit, facilitate additional meritorious research, and lead to formulation of policy and programs in India and elsewhere that will improve maternal, neonatal, infant and childhood health status. The CCHS-JNMC Research Unit has been a highly productive partner in the research agenda of the Global Network for over 10 years and the unit can be a source of future Global Network strength and credibility.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10HD076457-02
Application #
8672666
Study Section
Special Emphasis Panel (ZHD1-DSR-M (54))
Program Officer
Koso-Thomas, Marion
Project Start
2013-07-01
Project End
2018-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
2
Fiscal Year
2014
Total Cost
$698,031
Indirect Cost
$44,862
Name
Christiana Care Health Services, Inc.
Department
Type
DUNS #
077069243
City
Newark
State
DE
Country
United States
Zip Code
19713
Althabe, Fernando; Belizán, José M; McClure, Elizabeth M et al. (2015) A population-based, multifaceted strategy to implement antenatal corticosteroid treatment versus standard care for the reduction of neonatal mortality due to preterm birth in low-income and middle-income countries: the ACT cluster-randomised trial. Lancet 385:629-39
Bang, Akash; Bellad, Roopa; Gisore, Peter et al. (2014) Implementation and evaluation of the Helping Babies Breathe curriculum in three resource limited settings: does Helping Babies Breathe save lives? A study protocol. BMC Pregnancy Childbirth 14:116
Seale, Anna C; Blencowe, Hannah; Manu, Alexander A et al. (2014) Estimates of possible severe bacterial infection in neonates in sub-Saharan Africa, south Asia, and Latin America for 2012: a systematic review and meta-analysis. Lancet Infect Dis 14:731-41
Althabe, Fernando; Belizán, José M; Buekens, Pierre et al. (2014) Antenatal corticosteroids to reduce preterm deaths in low-income settings. Lancet Glob Health 2:e444
Saleem, Sarah; McClure, Elizabeth M; Goudar, Shivaprasad S et al. (2014) A prospective study of maternal, fetal and neonatal deaths in low- and middle-income countries. Bull World Health Organ 92:605-12
Hambidge, K Michael; Krebs, Nancy F; Westcott, Jamie E et al. (2014) Preconception maternal nutrition: a multi-site randomized controlled trial. BMC Pregnancy Childbirth 14:111
Marete, Irene; Tenge, Constance; Pasha, Omrana et al. (2014) Perinatal outcomes of multiple-gestation pregnancies in Kenya, Zambia, Pakistan, India, Guatemala, and Argentina: a global network study. Am J Perinatol 31:125-32