Under a cooperative agreement with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Christiana Care Health Services, Inc. (CCHS) and its partner, Jawaharlal Nehru Medical College (JNMC) of KLE. University, have the long-term objective of continued participation in the Global Network for Women's and Children's Health Research and continued collaboration in the operation of the CCHS-JNMC Research Unit. As a member of a multicenter international research network, the CCHS-JNMC Research Unit will conduct randomized clinical trials and intervention studies focused on reducing major risks to maternal, neonatal, infant, and early childhood health in low and lower-middle income countries. In collaboration with other Global Network participants, CCHS and JNMC will work to strengthen the Global Network research infrastructure, to increase the capacity for women's and children's health research, and to expand scientific knowledge that will lead to improved health practices and outcomes for women, infants, and children.
Specific aims of the CCHS-JNMC Research Unit during the next five-year Global Network funding cycle include: ?To provide for continued growth and development of the CCHS-JNMC RU which oversees the women's and children's health research program based at JNMC in Belgaum, Karnataka India, and to ensure sustainability of the research infrastructure at JNMC, integrated within the larger KLE University, and extending into surrounding districts served by JNMC and the University; ?To strengthen the Global Network and its role in international collaborative research by participating in creation of a significant GN research agenda and designing, developing, obtaining support for implementation, and conducting multiple, common research protocols which address the major causes of morbidity and mortality in women and young children in the developing world; ?To identify and address gaps in maternal and child research and, with other GN participants, to collaboratively implement and evaluate promising health interventions, formative and translational studies, including implementation research;and to disseminate findings.

Public Health Relevance

Continued participation in Global Network activities will strengthen the research capabilities of the CCHSJNMC Research Unit, facilitate additional meritorious research, and lead to formulation of policy and programs in India and elsewhere that will improve maternal, neonatal, infant and childhood health status. The CCHS-JNMC Research Unit has been a highly productive partner in the research agenda of the Global Network for over 10 years and the unit can be a source of future Global Network strength and credibility.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Cooperative Clinical Research--Cooperative Agreements (U10)
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Special Emphasis Panel (ZHD1-DSR-M (54))
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Koso-Thomas, Marion
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Christiana Care Health Services, Inc.
United States
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Bang, Akash; Patel, Archana; Bellad, Roopa et al. (2016) Helping Babies Breathe (HBB) training: What happens to knowledge and skills over time? BMC Pregnancy Childbirth 16:364
Hibberd, Patricia L; Hansen, Nellie I; Wang, Marie E et al. (2016) Trends in the incidence of possible severe bacterial infection and case fatality rates in rural communities in Sub-Saharan Africa, South Asia and Latin America, 2010-2013: a multicenter prospective cohort study. Reprod Health 13:65
Goldenberg, Robert L; Thorsten, Vanessa R; Althabe, Fernando et al. (2016) The global network antenatal corticosteroids trial: impact on stillbirth. Reprod Health 13:68
Berrueta, Mabel; Hemingway-Foday, Jennifer; Thorsten, Vanessa R et al. (2016) Use of antenatal corticosteroids at health facilities and communities in low-and-middle income countries. Reprod Health 13:66
Althabe, Fernando; Thorsten, Vanessa; Klein, Karen et al. (2016) The Antenatal Corticosteroids Trial (ACT)'s explanations for neonatal mortality - a secondary analysis. Reprod Health 13:62
Klein, Karen; McClure, Elizabeth M; Colaci, Daniela et al. (2016) The Antenatal Corticosteroids Trial (ACT): a secondary analysis to explore site differences in a multi-country trial. Reprod Health 13:64
Pasha, Omrana; Goudar, Shivaprasad S; Patel, Archana et al. (2015) Postpartum contraceptive use and unmet need for family planning in five low-income countries. Reprod Health 12 Suppl 2:S11
Dhaded, Sangappa M; Somannavar, Manjunath S; Vernekar, Sunil S et al. (2015) Neonatal mortality and coverage of essential newborn interventions 2010 - 2013: a prospective, population-based study from low-middle income countries. Reprod Health 12 Suppl 2:S6
Althabe, Fernando; Belizán, José M; McClure, Elizabeth M et al. (2015) A population-based, multifaceted strategy to implement antenatal corticosteroid treatment versus standard care for the reduction of neonatal mortality due to preterm birth in low-income and middle-income countries: the ACT cluster-randomised trial. Lancet 385:629-39
Goudar, Shivaprasad S; Derman, Richard J; Honnungar, Narayan V et al. (2015) An Intervention to Enhance Obstetric and Newborn Care in India: A Cluster Randomized-Trial. Matern Child Health J 19:2698-706

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