The Eunice Kennedy Shriver National Institute of Child Health and Human Development Global Network for Women's and Children's Health Research (GN) is a cooperative multicenter network formed to conduct clinical research in low resource countries with the aim of improving health and well-being of mothers and children. Indiana University has partnered with Moi University in Kenya to participate as a Global Network partner since 2008. During these five years the lU-Moi University partnership has established an efficient, productive site in Sub-Saharan Africa. The site consists of 16 clusters located in rural Western Kenya. It has contributed approximately 33,000 subjects to the Maternal Neonatal Health Registry database (MNH Registry), 3rd. most of The 7 Global Network sites. The consent rate is greater than 99%. Delivery outcomes are obtained in 96.6% of registered women, and 42 day follow-up is obtained in 98.2%. The partnership has successfully participated in one completed study and is currently participating in 2 ongoing GN studies. The principal Investigators of the Kenya site are Edward A. Liechty, Professor of Pediatrics at Indiana University School of Medicine, and Fabian Esamai, Professor of Child Health and Principal of the College of Health Sciences, Moi University, Eldoret, Kenya. Dr. Liechty and Professor Esamai have established a productive scientific endeavor based on a long term relationship of mutual respect and cooperation. Their collaboration began in 2003, when Dr. Liechty was a Fulbright Research Scholar at Moi University. At the time Professor Esamai was head of the Department of Child Health and Pediatrics. Since then Professor Esamai has been Dean of the School of Medicine (2006-2009) and most recently has been appointed the inaugural Principal (i.e. Vice Chancellor) of the newly established Moi University College of Health Sciences. In addition to this position within Moi University, Professor Esamai also is a frequent consultant to the Kenya Ministry of Health and the World Health Organization. Moi University has an excellent existing research infrastructure, including a duly constituted IRB and a fully functional grants financial management office. The site is a strong partner in the Global Network.

Public Health Relevance

The Indiana University-Moi University partnership will continue to serve as a site for multicenter international clinical research in Women's and Children's health. Particular focus will be on culturally appropriate public health interventions to improve the outcome of pregnancy for women in low resource countries.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
3U10HD076461-01S1
Application #
8727729
Study Section
Special Emphasis Panel (ZHD1-DSR-M (54))
Program Officer
Koso-Thomas, Marion
Project Start
2013-05-25
Project End
2018-04-30
Budget Start
2013-05-25
Budget End
2014-04-30
Support Year
1
Fiscal Year
2013
Total Cost
$249,223
Indirect Cost
$4,861
Name
Indiana University-Purdue University at Indianapolis
Department
Pediatrics
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
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Hibberd, Patricia L; Hansen, Nellie I; Wang, Marie E et al. (2016) Trends in the incidence of possible severe bacterial infection and case fatality rates in rural communities in Sub-Saharan Africa, South Asia and Latin America, 2010-2013: a multicenter prospective cohort study. Reprod Health 13:65
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Bose, Carl L; Bauserman, Melissa; Goldenberg, Robert L et al. (2015) The Global Network Maternal Newborn Health Registry: a multi-national, community-based registry of pregnancy outcomes. Reprod Health 12 Suppl 2:S1
Harrison, Margo S; Ali, Sumera; Pasha, Omrana et al. (2015) A prospective population-based study of maternal, fetal, and neonatal outcomes in the setting of prolonged labor, obstructed labor and failure to progress in low- and middle-income countries. Reprod Health 12 Suppl 2:S9
Bauserman, Melissa; Lokangaka, Adrien; Thorsten, Vanessa et al. (2015) Risk factors for maternal death and trends in maternal mortality in low- and middle-income countries: a prospective longitudinal cohort analysis. Reprod Health 12 Suppl 2:S5
Marete, Irene; Tenge, Constance; Chemweno, Carolyne et al. (2015) Lost to follow-up among pregnant women in a multi-site community based maternal and newborn health registry: a prospective study. Reprod Health 12 Suppl 2:S4

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